The LIMCR (Laboratory for Immunological and Molecular Cancer Research), which is integrated in the Third Medical Department of the Paracelsus Medical University Hospital, opened its doors in 2005 and has its research focus on chronic lymphocytic leukemia (CLL), myelodysplastic syndromes (MDS) and acut myeloid leukemia (AML). The LIMCR maintains a close connection with the clinic to ensure maximum synergy and efficacy in cancer therapy.
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Group leader: Dr. Nadja Zaborsky
“In principle, the cells of the immune system (NK cells, T cells) are able to combat cancer. However, cancer cells developed mechanisms for immune escape, which enables unhindered tumor growth. Immune therapies aim at reinvigorating the body’s own immune system to improve cancer treatment. In our working group, we are analyzing the interplay between genetic changes in cancer cells and alterations in immune cell composition and functionality, which is important to improve current immune therapy approaches.”