Publikationen
Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial.
Borchmann P, Ferdinandus J, Schneider G, Moccia A, Greil R, Hertzberg M, Schaub V, Hüttmann A, Keil F, Dierlamm J, Hänel M, Novak U, Meissner J, Zim-mermann A, Mathas S, Zijlstra JM, Fosså A, Viardot A, Hertenstein B, Martin S, Giri P, Scholl S, Topp MS, Jung W, Vucinic V, Beck HJ, Kerkhoff A, Unger B, Rank A, Schroers R, Zum Büschenfelde CM, de Wit M, Trautmann-Grill K, Kamper P, Molin D, Kreissl S, Kaul H, von Tresckow B, Borchmann S, Behringer K, Fuchs M, Rosenwald A, Klapper W, Eich HT, Baues C, Zomas A, Hallek M, Dietlein M, Kobe C, Diehl V; German Hodgkin Study Group; Swiss Group for Clinical Cancer Re-search; Arbeitsgemeinschaft Medikamentöse Tumortherapie; Nordic Lymphoma Group; Australasian Leukaemia and Lymphoma Group.
Lancet. 2024 Jul 3:S0140-6736(24)01315-1. doi: 10.1016/S0140-6736(24)01315-1. Online ahead of print. PMID: 38971175.
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QoL during KTd or KRd induction followed by K maintenance or observation in transplant noneligible patients with newly diagnosed multiple myeloma: Longitudinal and cross-sectional analysis of the randomized AGMT 02 study.
Ludwig H, Melchardt T, Schweitzer I, Sormann S, Schreder M, Andel J, Hartmann B, Zojer N, Schöffmann L, Gunsilius E, Podar K, Egle A, Willenbacher W, Wöll E, Ruckser R, Bozic B, Krauth MT, Petzer A, Schmitt C, Machherndl-Spandl S, Agis H, Fillitz M, Wang SY, Knop S, Greil R.
EJHaem. 2024 May 17;5(3):494-504. doi: 10.1002/jha2.925. eCollection 2024 Jun. PMID: 38895059.
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Emicizumab versus immunosuppressive therapy for the management of ac-quired hemophilia A.
Hart C, Klamroth R, Sachs UJ, Greil R, Knoebl P, Oldenburg J, Miesbach W, Pfrepper C, Trautmann-Grill K, Pekrul I, Holstein K, Eichler H, Weigt C, Schipp D, Werwitzke S, Tiede A.
J Thromb Haemost. 2024 Jun 25:S1538-7836(24)00368-4. doi: 10.1016/j.jtha.2024.06.010. Online ahead of print. PMID: 38936699.
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Combined DNA Analysis from Stool and Blood Samples Improves Tumor Tracking and Assessment of Clonal Heterogeneity in Localized Rectal Cancer Patients.
Parigger T, Gassner FJ, Drothler S, Scherhäufl C, Hödlmoser A, Schultheis L, Bakar AA, Huemer F, Greil R, Geisberger R, Weiss L, Zaborsky N.
Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338241252706. doi: 10.1177/15330338241252706. PMID: 38766867.
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Prediction of survival after neoadjuvant therapy in locally advanced rectal cancer - a retrospective analysis.
Piringer G, Ponholzer F, Thaler J, Bachleitner-Hofmann T, Rumpold H, de Vries A, Weiss L, Greil R, Gnant M, Öfner D.
Front Oncol. 2024 May 16;14:1374592. doi: 10.3389/fonc.2024.1374592. eCollection 2024. PMID: 38817890.
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Nivolumab + Ipilimumab as Immunotherapeutic Boost in Metastatic Urothelial Carcinoma: A Nonrandomized Clinical Trial.
Grimm MO, Schostak M, Grün CB, Loidl W, Pichler M, Zimmermann U, Schmitz-Dräger B, Steiner T, Roghmann F, Niegisch G, Bolenz C, Schmitz M, Baretton G, Leucht K, Schumacher U, Foller S, Zengerling F, Meran J; TITAN-TCC Study Group.
JAMA Oncol. 2024 May 9:e240938. doi: 10.1001/jamaoncol.2024.0938. Online ahead of print. PMID: 38722641.
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Correction: Is the CTS5 a helpful decision-making tool in the extended adjuvant therapy setting?
Wimmer K, Hlauschek D, Balic M, Pfeiler G, Greil R, Singer CF, Halper S, Steger G, Suppan C, Gampenrieder SP, Helfgott R, Egle D, Filipits M, Jakesz R, Sölkner L, Fesl C, Gnant M, Fitzal F.
Breast Cancer Res Treat. 2024 May 5. doi: 10.1007/s10549-024-07351-5. Online ahead of print. PMID: 38704775.
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Oncogenic MTOR signaling axis compensates BTK inhibition in a Chronic Lymphocy-tic Leukemia patient with Richter Transformation: A Case Report and Review of the Literature.
Parigger T, Drothler S, Scherhäufl C, Gassner FJ, Schubert M, Steiner M, Höpner JP, Hödlmoser A, Schultheis L, Abu Bakar A, Neureiter D, Pleyer L, Egle A, Greil R, Geisberger R, Zaborsky N.
Acta Haematol. 2024 Feb 24. doi: 10.1159/000537791. Online ahead of print. PMID: 38402867.
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Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy.
Lafarge MW, Domingo E, Sirinukunwattana K, Wood R, Samuel L, Murray G, Richman SD, Blake A, Sebag-Montefiore D, Gollins S, Klieser E, Neureiter D, Huemer F, Greil R, Dunne P, Quirke P, Weiss L, Rittscher J, Maughan T, Koelzer VH.
NPJ Precis Oncol. 2024 Apr 9;8(1):89. doi: 10.1038/s41698-024-00580-3. PMID: 38594327.
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Enhancing anti-CD274 (PD-L1) targeting through combinatorial immunotherapy with bispecific antibodies and fusion proteins: from preclinical to phase II clinical trials.
Kiem D, Ocker M, Greil R, Neureiter D, Melchardt T.
Expert Opin Investig Drugs. 2024 Feb 23:1-14. doi: 10.1080/13543784.2024.2319317. Online ahead of print. PMID: 38354028.
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Comment on: Incidence, clinicopathological features, and clinical outcomes of low HER2 expressed, inoperable, advanced, or recurrent gastric/gastroesophageal junction adenocarcinoma.
Huemer F, Weiss L, Regitnig P, Winder T, Schmitt CA, Thaler J, Wöll E, Greil R.
ESMO Open. 2024 Mar 19;9(4):102973. doi: 10.1016/j.esmoop.2024.102973. Online ahead of print. PMID: 38507896.
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Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus con-current chemoradiotherapy in patients with locally advanced squamous cell car-cinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial.
Machiels JP, Tao Y, Licitra L, Burtness B, Tahara M, Rischin D, Alves G, Lima IPF, Hughes BGM, Pointreau Y, Aksoy S, Laban S, Greil R, Burian M, Hetnał M, Delord JP, Mesía R, Taberna M, Waldron JN, Simon C, Grégoire V, Harrington KJ, Swaby RF, Zhang Y, Gumuscu B, Bidadi B, Siu LL; KEYNOTE-412 Investigators.
Lancet Oncol. 2024 Mar 29:S1470-2045(24)00100-1. doi: 10.1016/S1470-2045(24)00100-1. Online ahead of print. PMID: 38561010.
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Randomized comparison between KTd and KRd induction therapy followed by maintenance therapy with K or observation in transplant-ineligible patients with newly diagnosed multiple myeloma.
Ludwig H, Melchardt T, Sormann S, Schreder M, Andel J, Hartmann B, Tinchon C, Zojer N, Gunsilius E, Podar K, Egle A, Willenbacher W, Wöll E, Ruckser R, Bo-zic B, Krauth MT, Petzer A, Schmitt C, Machherndl-Spandl S, Agis H, Fillitz M, Wang SY, Zabernigg A, Knop S, Paiva B, Greil R.
Am J Hematol. 2024 May;99(5):1008-1011. doi: 10.1002/ajh.27280. Epub 2024 Feb 29. PMID: 38425185.
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Pre-treatment 68 Ga-PSMA-11 PET/CT Prognostic Value in Predicting Response to 177Lu-PSMA-I&T Therapy and Patient Survival.
Eisazadeh R, Mirshahvalad SA, Schwieghofer-Zwink G, Hehenwarter L, Rendl G, Gampenrieder S, Greil R, Pirich C, Beheshti M.
Mol Imaging Biol. 2024 Feb 15. doi: 10.1007/s11307-024-01900-6. Online ahead of print. PMID: 3836099.
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Cardiac Adverse Events and Remdesivir in Hospitalized Patients with Coronavi-rus Disease 2019 (COVID-19): A Post Hoc Safety Analysis of the Randomized DisCoVeRy Trial.
Terzić V, Miantezila Basilua J, Billard N, de Gastines L, Belhadi D, Fougerou-Leurent C, Peiffer-Smadja N, Mercier N, Delmas C, Ferrane A, Dechanet A, Pois-sy J, Espérou H, Ader F, Hites M, Andrejak C, Greil R, Paiva JA, Staub T, Tacconel-li E, Burdet C, Costagliola D, Mentré F, Yazdanpanah Y, Diallo A; DisCoVeRy stu-dy group.
Clin Infect Dis. 2024 Mar 29:ciae170. doi: 10.1093/cid/ciae170. Online ahead of print. PMID: 38552208.
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A phase 1 study of acapatamab, a half-life extended, PSMA-targeting bispecific T-cell engager for metastatic castration-resistant prostate cancer.
Dorff T, Horvath LG, Autio K, Bernard-Tessier A, Rettig MB, Machiels JP, Bilen MA, Lolkema MP, Adra N, Rottey S, Greil R, Matsubara N, Tan DSW, Wong A, Uemura H, Lemech C, Meran J, Yu Y, Minocha M, McComb M, Penny HL, Gupta V, Hu X, Jurida G, Kouros-Mehr H, Janát-Amsbury MM, Eggert T, Tran B.
Clin Cancer Res. 2024 Feb 1. doi: 10.1158/1078-0432.CCR-23-2978. Online ahead of print. PMID: 38300720.
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Is the CTS5 a helpful decision-making tool in the extended adjuvant therapy setting?
Wimmer K, Hlauschek D, Balic M, Pfeiler G, Singer CF, Halper S, Steger G, Suppan C, Gampenrieder SP, Helfgott R, Egle D, Filipits M, Jakesz R, Sölkner L, Fesl C, Gnant M, Fitzal F, Greil R.
Breast Cancer Res Treat. 2024 Jan 25. doi: 10.1007/s10549-023-07186-6. Online ahead of print. PMID: 38273214.
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Unraveling Resistance to Immunotherapy in MSI-High Colorectal Cancer.
Heregger R; Huemer F; Steiner M; Gonzalez-Martinez A; Greil R; Weiss L.
Cancers (Basel). 2023 Oct 21;15(20):5090. doi: 10.3390/cancers15205090.
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Treatment Algorithm for Patients With Gastric Adenocarcinoma: Austrian Consensus on Systemic Therapy - An Update.
Wöll E; Amann A; Eisterer W; Gerger A; Grünberger B; Rumpold H; Weiss L; Winder T; Greil R; Prager GW.
Anticancer Res. 2023 Jul;43(7):2889-2897. doi: 10.21873/anticanres.16460.
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BendaEAM versus BEAM as conditioning regimen for ASCT in patients with relapsed lymphoma (BEB): a multicentre; randomised; phase 2 trial.
Keil F; Müller AMS; Berghold A; Riedl R; Buxhofer-Ausch V; Schuster J; Vorburger C; Böhm A; Panny M; Nösslinger T; Greil R; Samaras P; Bencker C; Rütti M; Pabst T.
EClinicalMedicine. 2023 Nov 19:66:102318. doi: 10.1016/j.eclinm.2023.102318. eCollection 2023 Dec.
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Association between SARS-CoV-2 viral kinetics and clinical score evolution in hospitalized patients.
Néant N; Lingas G; Gaymard A; Belhadi D; Hites M; Staub T; Greil R; Paiva JA; Poissy J; Peiffer-Smadja N; Costagliola D; Yazdanpanah Y; Bouscambert-Duchamp M; Gagneux-Brunon A; Ader F; Mentré F; Wallet F; Burdet C; Guedj J.
CPT Pharmacometrics Syst Pharmacol. 2023 Dec;12(12):2027-2037. doi: 10.1002/psp4.13051. Epub 2023 Oct 11.
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Phase I/Ib; open-label; multicenter; dose-escalation study of the anti-TGF-β monoclonal antibody; NIS793; in combination with spartalizumab in adult patients with advanced tumors.
Bauer TM; Santoro A; Lin CC; Garrido-Laguna I; Joerger M; Greil R; Spreafico A; Yau T; Goebeler ME; Hütter-Krönke ML; Perotti A; Juif PE; Lu D; Barys L; Cremasco V; Pelletier M; Evans H; Fabre C; Doi T.
J Immunother Cancer. 2023 Nov 29;11(11):e007353. doi: 10.1136/jitc-2023-007353.
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Interim PET-guided treatment for early-stage NLPHL: a subgroup analysis of the randomized GHSG HD16 and HD17 studies.
Eichenauer DA; Bühnen I; Baues C; Kobe C; Kaul H; Greil R; Moccia A; Zijlstra JM; Her-tenstein B; Topp MS; Just M; von Tresckow B; Eich HT; Fuchs M; Dietlein M; Hartmann S; Engert A; Borchmann P.
Blood. 2023 Aug 10;142(6):553-560. doi: 10.1182/blood.2023019939.
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Emicizumab prophylaxis in patients with acquired haemophilia A (GTH-AHA-EMI): an open-label; single-arm; multicentre; phase 2 study.
Tiede A; Hart C; Knöbl P; Greil R; Oldenburg J; Sachs UJ; Miesbach W; Pfrepper C; Trautmann-Grill K; Holstein K; Pilch J; Möhnle P; Schindler C; Weigt C; Schipp D; May M; Dobbelstein C; Pelzer FJ; Werwitzke S; Klamroth R.
Lancet Haematol. 2023 Nov;10(11):e913-e921. doi: 10.1016/S2352-3026(23)00280-6. Epub 2023 Oct 16.
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Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised; open-label; multicentre; phase 3 trial.
Döhner H; Weber D; Krzykalla J; Fiedler W; Kühn MWM; Schroeder T; Mayer K; Lübbert M; Wattad M; Götze K; Fransecky L; Koller E; Wulf G; Schleicher J; Ring-hoffer M; Greil R; Hertenstein B; Krauter J; Martens UM; Nachbaur D; Samra MA; Machherndl-Spandl S; Basara N; Leis C; Schrade A; Kapp-Schwoerer S; Cocciardi S; Bullinger L; Thol F; Heuser M; Paschka P; Gaidzik VI; Saadati M; Benner A; Schlenk RF; Döhner K; Ganser A.
Lancet Haematol. 2023 Jul;10(7):e495-e509. doi: 10.1016/S2352-3026(23)00089-3. Epub 2023 May 12.
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Tumor Treating Fields therapy with standard systemic therapy versus standard systemic therapy alone in metastatic non-small-cell lung cancer following progression on or after platinum-based therapy (LUNAR): a randomised, open-label, pivotal phase 3 study.
Leal T; Kotecha R; Ramlau R; Zhang L; Milanowski J; Cobo M; Roubec J; Petruzelka L; Havel L; Kalmadi S; Ward J; Andric Z; Berghmans T; Gerber DE; Kloecker G; Panikkar R; Aerts J; Delmonte A; Pless M; Greil R; Rolfo C; Akerley W; Eaton M; Iqbal M; Langer C.
Lancet Oncol. 2023 Sep;24(9):1002-1017. doi: 10.1016/S1470-2045(23)00344-3.
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Impact of individualized treatment on recovery from fatigue and return to work in survivors of advanced-stage Hodgkin's lymphoma: results from the randomized international GHSG HD18 trial.
Ferdinandus, J; Müller, H; Damaschin, C; Jacob, AS; Meissner, J; Krasniqi, F; Mey, U; Schöndube, D; Thiemer, J; Mathas, S; Zijlstra, J; Greil, R; Feu-ring-Buske, M; Markova, J; Rüffer, JU; Kobe, C; Eich, HT; Baues, C; Fuchs, M; Borchmann, P; Behringer, K.
Ann Oncol. 2023 Dec 5:S0923-7534(23)05102-5. doi: 10.1016/j.annonc.2023.11.014. Online ahead of print.
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Follow-up of the GHSG HD16 trial of PET-guided treatment in early-stage favorable Hodgkin lymphoma.
Fuchs, M; Jacob, AS; Kaul, H; Kobe, C; Kuhnert, G; Pabst, T; Greil, R; Brö-ckelmann, PJ; Topp, MS; Just, M; Hertenstein, B; Soekler, M; Vogelhuber, M; Zijlstra, JM; Keller, UB; Krause, SW; Dührsen, U; Meissner ,J; Viardot, A; Eich, HT; Baues, C; Diehl, V; Rosenwald, A; Buehnen, I; von Tresckow, B; Dietlein, M; Borchmann, P; Engert, A; Eichenauer, DA.
Leukemia. 2024 Jan;38(1):160-167. doi: 10.1038/s41375-023-02064-y. E-pub 2023 Oct 16.
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Interim analysis of ELEANOR (n=200): a multi-national; prospective; non-interventional study (NIS) among patients with HER2+and HR+ early breast cancer (eBC) treated with extended adjuvant neratinib.
Bartsch, R; Harbeck, N; Wrobel, D; Zaiss, M; Terhaag, J; Guth, D; Distelrath, A; Wuerstlein, R; Zahn, MO; Luftner, D; Schwitter, M; Balic, M; Jackisch, C; Muller, V; Rinnerthaler, G; Schmidt, M; Zaman, K; Schinkothe, T; Gorray, M; Breitenstein, U.
The Breast 62S1 (2023) S20–S21.
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Updated Austrian treatment algorithm for metastatic triple-negative breast cancer.
Bartsch, R; Rinnerthaler, G; Petru, E; Egle, D; Gnant, M; Balic, M; Sliwa, T; Singer, C.
Wien Klin Wochenschr. 2023 Sep 8. doi: 10.1007/s00508-023-02254-9. Online ahead of print.
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Position paper on CDK4/6 inhibitors in early breast cancer.
Gnant, M; Singer, CF; Rinnerthaler, G; Pfeiler, G; Egle, D; Balic, M; Bartsch, R.
memo 16, 135–144 (2023). https://doi.org/10.1007/s12254-023-00878-1.
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Systemic treatment of patients with locally advanced or metastatic cho-langiocarcinoma - an Austrian expert consensus statement.
Taghizadeh, H; Djanani, A; Eisterer, W; Gerger, A; Gruenberger, B; Gruen-berger, T; Rumpold, H; Weiss, L; Winder, T; Woll, E; Prager, GW.
Front Oncol. 2023 Aug 30:13:1225154. doi: 10.3389/fonc.2023.1225154. eCollection 2023.
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Prognostic value of [18F]FDG PET/CT on treatment response and pro-gression-free survival of gastroesophageal cancer patients undergoing perioperative FLOT chemotherapy.
Mirshahvalad, SA; Seyedinia, SS; Huemer, F; Schweighofer-Zwink, G; Koch, O; Hitzl, W; Weiss, L; Emannuel, K; Greil, R; Pirich, C; Beheshti, M.
Eur J Radiol. 2023 Jun:163:110843. doi: 10.1016/j.ejrad.2023.110843. Epub 2023 Apr 20.
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Inactivation of TRPM7 Kinase Targets AKT Signaling and Cyc-looxygenase-2 Expression in Human CML Cells.
Hoeger, B; Nadolni, W; Holting, K; Hampe, S; Fraticelli, M; Zaborsky, N; Imm-ler, R; Chubanov, V; Geisberger, R; Greil, R; Sperandio, M; Boekhoff, I; Gu-dermann, T; Zierler, S.
Function, Volume 4, Issue 6, 2023, zqad053, https://doi.org/10.1093/function/zqad053
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Pembrolizumab Plus Olaparib for Patients With Previously Treated and Biomarker-Unselected Metastatic Castration-Resistant Prostate Cancer: The Randomized, Open-Label, Phase III KEYLYNK-010 Trial.
Antonarakis ES; Park SH; Goh JC; Shin SJ; Lee JL; Mehra N; McDermott R; Sala-Gonzalez N; Fong PC; Greil R; Retz M; Sade JP; Yanez P; Huang YH; Begbie SD; Gafanov RA; De Santis M; Rosenbaum E; Kolinsky MP; Rey F; Chiu KY; Roubaud G; Kramer G; Sumitomo M; Massari F; Suzuki H; Qiu P; Zhang J; Kim J; Poehlein CH; Yu EY.
J Clin Oncol. 2023 Aug 1;41(22):3839-3850. doi: 10.1200/JCO.23.00233. Epub 2023 Jun 8.PMID: 37290035
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Is the CTS5 a helpful decision-making tool in the extended adjuvant therapy setting?
Wimmer, K; Hlauschek, D; Balic, M; Pfeiler, G; Strobl-Kacerovsky, S; Greil, R; Singer, CF; Halper, S; Steger, G; Suppan, C; Gampenrieder, SP; Helfgott, R; Egle, D; Filipits, M; Jakesz, R; Solkner, L; Fesl, C; Gnant, M; Fitzal, F.
Breast Cancer Res Treat (2024). https://doi.org/10.1007/s10549-023-07186-6.
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Spatial predictors of immunotherapy response in triple-negative breast cancer.
Wang, XQ; Danenberg, E; Huang, CS; Egle, D; Callari, M; Bermejo, B; Dugo, M; Zamagni, C; Thill, M; Anton, A; Zambelli, S; Russo, S; Ciruelos, EM; Greil, R; Gyorffy, B; Semiglazov, V; Colleoni, M; Kelly, CM; Mariani, G; Del Mastro, L; Biasi, O; Seitz, RS; Valagussa, P; Viale, G; Gianni, L; Bianchini, G; Ali, HR.
Nature. 2023 Sep;621(7980):868-876. doi: 10.1038/s41586-023-06498-3. E-pub 2023 Sep 6.
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Comparison of gemcitabine plus oxaliplatin versus gemcitabine plus nab-paclitaxel as first-line chemotherapy for advanced pancreatic adeno-carcinoma: A single-center retrospective analysis.
Schlick, K; Gantschnigg, A; Seymer, A; Huemer, F; Greil, R; Weiss, L.
Cancer Med. 2023 Aug;12(16):16997-17004. doi: 10.1002/cam4.6334. Epub 2023 Aug 3.
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Cox proportional hazards deep neural network identifies peripheral blood complete remission to be at least equivalent to morphologic complete remission in predicting outcomes of patients treated with azacitidine-A prospective cohort study by the AGMT.
Pleyer, L; Vaisband, M; Drost, M; Pfeilstöcker, M; Stauder, R; Heibl, S; Sill, H; Girschikofsky, M; Stampfl-Mattersberger, M; Pichler, A; Hartmann, B; Petzer, A; Schreder, M; Schmitt, CA; Vallet, S; Melchardt, T; Zebisch, A; Pichler, P; Zaborsky, N; Machherndl-Spandl, S; Wolf, D; Keil, F; Hasenauer, J; Larcher-Senn, J; Greil, R.
Am J Hematol. 2023 Nov;98(11):1685-1698. doi: 10.1002/ajh.27046. Epub 2023 Aug 7.
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Management of metastatic colorectal cancer in patients ≥70 years - a single center experience.
Huemer, F; Dunkl, C; Rinnerthaler, G; Schlick, K; Heregger, R; Emmanuel, K; Neureiter, D; Klieser, E; Deutschmann, M; Roeder, F; Greil, R; Weiss, L.
Front Oncol. 2023 Jul 25:13:1222951. doi: 10.3389/fonc.2023.1222951. eCollection 2023.
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Erythropoiesis-stimulating agents-benefits and harms in the treatment of anemia in cancer patients.
Heregger, R; Greil, R.
memo 16, 259–262 (2023). https://doi.org/10.1007/s12254-023-00902-4.
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Validation of genetic variants from NGS data using deep convolutional neural networks.
Vaisband, M; Schubert, M; Gassner, FJ; Geisberger, R; Greil, R; Zaborsky, N; Hasenauer, J.
BMC Bioinformatics. 2023 Apr 20;24(1):158. doi: 10.1186/s12859-023-05255-7.
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Body composition dynamics and impact on clinical outcome in gastric and gastro-esophageal junction cancer patients undergoing perioperati-ve chemotherapy with the FLOT protocol.
Huemer, F; Hecht, S; Scharinger, B; Schlintl, V; Rinnerthaler, G; Schlick, K; Heregger, R; Melchardt, T; Wimmer, A; Mühlbacher, I; Koch, OO; Neureiter, D; Klieser, E; Seyedinia, S; Beheshti, M; Greil, R; Weiss, L.
J Cancer Res Clin Oncol. 2023 Jul;149(7):3051-3064. doi: 10.1007/s00432-022-04096-w. Epub 2022 Jul 21.
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Myeloid NGS Analyses of Paired Samples from Bone Marrow and Peri-pheral Blood Yield Concordant Results: A Prospective Cohort Analysis of the AGMT Study Group.
Jansko-Gadermeir, B; Leisch, M; Gassner, FJ; Zaborsky, N; Dillinger, T; Hut-ter, S; Risch, A; Melchardt, T; Egle, A; Drost, M; Larcher-Senn, J; Greil, R; Pleyer, L.
Cancers (Basel) . 2023 Apr 14;15(8):2305. doi: 10.3390/cancers15082305.
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Pretreatment 18-FDG-PET/CT parameters can serve as prognostic ima-ging biomarkers in recurrent NSCLC patients treated with reirradiation-chemoimmunotherapy.
Grambozov, B; Kalantari, F; Beheshti, M; Stana, M; Karner, J; Ruznic, E; Zellinger, B; Sedlmayer, F; Rinnerthaler, G; Zehentmayr, F.
Radiother Oncol. 2023 Aug;185:109728. doi: 10.1016/j.radonc.2023.109728. Epub 2023 Jun 9.
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RE-MIND2: comparative effectiveness of tafasitamab plus lenalidomide versus polatuzumab vedotin/bendamustine/rituximab (pola-BR), CAR-T therapies, and lenalidomide/rituximab (R2) based on real-world data in patients with relapsed/refractory diffuse large B-cell lymphoma.
Nowakowski, GS; Yoon, DH; Mondello, P; Joffe, E; Peters, A; Fleury, I; Greil, R; Ku, MT; Marks, R; Kim, K; Zinzani, PL; Trotman, J; Sabatelli, L; Waltl, EE; Winderlich, M; Sporchia, A; Kurukulasuriya, NC; Cordoba, R; Hess, G; Salles, G.
Ann Hematol. 2023 Jul;102(7):1773-1787. doi: 10.1007/s00277-023-05196-4. Epub 2023 May 12.
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S-1 maintenance therapy in Caucasian patients with metastatic esopha-gogastric adenocarcinomaefinal results of the randomized AIO MATEO phase II trial.
Stocker, G; Lorenzen, S; Ettrich, T; Herz, AL; Longo, F; Kiani, A; Venerito, M; Trojan, J; Mahlberg, R; Moosmann, N; Chibaudel, B; Kubicka, S; Greil, R; Daum, S; Geissler, M; Larcher-Senn, J; Keller, G; Lordick, F; Haag, GM.
ESMO Open. 2023 Jun;8(3):101572. doi: 10.1016/j.esmoop.2023.101572. Epub 2023 Jun 2.
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Barriers to patient access of CAR T cell therapies in Austria.
Hopfinger, G; Rupp, B; Greil, R.
memo 16, 79–90 (2023). https://doi.org/10.1007/s12254-022-00859-w.
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How I treat diffuse large B-cell lymphoma.
Melchardt, T; Egle, A; Greil, R.
ESMO Open.2023 Feb;8(1):100750. doi: 10.1016/j.esmoop.2022.100750. Epub 2023 Jan 10.
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Health-Related Quality of Life as Assessed by the EQ-5D-5L Predicts Outcomes of Patients Treated with Azacitidine-A Prospective Cohort Study by the AGMT.
Pleyer, L; Heibl, S; Tinchon, C; Vallet, S; Schreder, M; Melchardt, T; Stute, N; Föhrenbach Quiroz, KT; Leisch, M; Egle, A; Scagnetti, L; Wolf, D; Beswick, R; Drost, M; Larcher-Senn, J; Grochtdreis, T; Vaisband, M; Hasenauer, J; Zaborsky, N; Greil, R; Stauder, R.
Cancers (Basel). 2023 Feb 22;15(5):1388. doi: 10.3390/cancers15051388.
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The Class IIA Histone Deacetylase (HDAC) Inhibitor TMP269 Downregulates Ribosomal Proteins and Has Anti-Proliferative and Pro-Apoptotic Effects on AML Cells.
Urwanisch, L; Unger, MS; Sieberer, H; Dang, HH; Neuper, T; Regl, C; Vetter, J; Schaller, S; Winkler, SM; Kerschbamer, E; Weichenberger, CX; Krenn, PW; Luciano, M; Pleyer, L; Greil, R; Huber, CG; Aberger, F; Horejs-Hoeck, J.
Cancers (Basel).2023 Feb 7;15(4):1039. doi: 10.3390/cancers15041039.
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Pembrolizumab With or Without Chemotherapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: Updated Results of the Phase III KEYNOTE-048 Study.
Harrington, KJ; Burtness, B; Greil, R; Soulieres, D; Tahara, M; de Castro, G; Psyrri, A; Brana, I; Baste, N; Neupane, P; Bratland, A; Fuereder, T; Hughes, BGM; Mesia, R; Ngamphaiboon, N; Rordorf, T; Ishak, WZW; Lin, JX; Gumuscu, B; Swaby, RF; Rischin, D.
J Clin Oncol.2023 Feb 1;41(4):790-802. doi: 10.1200/JCO.21.02508. Epub 2022 Oct 11.
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Does the number of 6-monthly adjuvant zoledronate infusions received affect treatment efficacy for early breast cancer? A sub-study of ABCSG-12.
Beltran-Bless, AA; Clemons, MJ; Fesl, C; Greil, R; Pond, GR; Balic, M; Vandermeer, L; Bjelic-Radisic, V; Singer, CF; Steger, GG; Helfgott, R; Egle, D; Sölkner, L; Gampenrieder, SP; Kacerovsky-Strobl, S; Suppan, C; Ritter, M; Rinnerthaler, G; Pfeiler, G; Fohler, H; Hlauschek, D; Hilton, J; Gnant, M.
Eur J Cancer. 2023 Feb;180:108-116. doi: 10.1016/j.ejca.2022.12.003. Epub 2022 Dec 10.
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Targets of autoantibodies in acquired hemophilia A are not restricted to factor VIII: data from the GTH-AH 01/2010 study.
Oleshko, O; Werwitzke, S; Klingberg, A; Witte, T; Eichler, H; Klamroth, R; Holstein, K; Hart, C; Pfrepper, C; Knoebl, P; Greil, R; Neumeister, P; Reipert, BM; Tiede, A.
Blood Adv.2023 Jan 10;7(1):122-130. doi: 10.1182/bloodadvances.2022008071.
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Real-world Data of Palliative First-line Checkpoint Inhibitor Therapy for Head and Neck Cancer.
Wagner, SM; Magnes, T; Melchardt, T; Kiem, D; Weiss, L; Neureiter, D; Wag-ner, C; Aretin, MB; Nemec, S; Gamerith, G; Pall, G; Greil, R; Fuereder, T.
Anticancer Res.2023 Mar;43(3):1273-1282. doi: 10.21873/anticanres.16274.
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Influence of HER2 expression on prognosis in metastatic triple-negative breast cancer-results from an international, multicenter analysis coordi-nated by the AGMT Study Group.
Gampenrieder, SP; Dezentjé, V; Lambertini, M; de Nonneville, A; Marhold, M; Le Du, F; Cortés Salgado, A; Alpuim Costa, D; Vaz Batista, M; Chic Ruché, N; Tinchon, C; Petzer, A; Blondeaux, E; Del Mastro, L; Targato, G; Bertucci, F; Gonçalves, A; Viret, F; Bartsch, R; Mannsbart, C; Deleuze, A; Robert, L; Saa-vedra Serrano, C; Gion Cortés, M; Sampaio-Alves, M; Vitorino, M; Pecen, L; Singer, C; Harbeck, N; Rinnerthaler, G; Greil, R.
ESMO Open. 2022 Dec 21;8(1):100747. doi: 10.1016/j.esmoop.2022.100747. Online ahead of print.
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Transcriptomic Profiling Identifies CD8(+ )T Cells in the Brain of Aged and Alzheimer?s Disease Transgenic Mice as Tissue-Resident Memory T Cells.
Altendorfer, B; Unger, MS; Poupardin, R; Hoog, A; Asslaber, D; Gratz, IK; Mrowetz, H; Benedetti, A; de Sousa, DMB; Greil, R; Egle, A; Gate, D; Wyss-Coray, T; Aigner, L.
J Immunol. 2022 Oct 1;209(7):1272-1285. doi: 10.4049/jimmunol.2100737. Epub 2022 Aug 31.
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How We Treat Localized Rectal Cancer-An Institutional Paradigm for To-tal Neoadjuvant Therapy.
Roeder, F; Gerum, S; Hecht, S; Huemer, F; Jäger, T; Kaufmann, R; Klieser, E; Koch, OO; Neureiter, D; Emmanuel, K; Sedlmayer, F; Greil, R; Weiss, L.
Cancers (Basel). 2022 Nov 21;14(22):5709. doi: 10.3390/cancers14225709.
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An early glimpse at azacitidine plus venetoclax for myelodysplastic syndromes.
Pleyer, L; Sekeres, MA.
Lancet Haematol. 2022 Oct;9(10):e714-e716. doi: 10.1016/S2352-3026(22)00252-6. Epub 2022 Sep 2.
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What is the management of resected cholangiocarcinoma in terms of intra- and postoperative status of tumor margins and lymph nodes? A current view.
Schlick, K; Neumayer, B; Neureiter, D.
Expert Rev Gastroenterol Hepatol. 2022 Nov-Dec;16(11-12):1019-1022. doi: 10.1080/17474124.2022.2155633. Epub 2022 Dec 13.
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Body composition dynamics and impact on clinical outcome in gastric and gastro-esophageal junction cancer patients undergoing perioperati-ve chemotherapy with the FLOT protocol.
Huemer, F; Hecht, S; Scharinger, B; Schlintl, V; Rinnerthaler, G; Schlick, K; Heregger, R; Melchardt, T; Wimmer, A; Mühlbacher, I; Koch, OO; Neureiter, D; Klieser, E; Seyedinia, S; Beheshti, M; Greil, R; Weiss, L.
J Cancer Res Clin Oncol. 2022 Jul 21. doi: 10.1007/s00432-022-04096-w. Online ahead of print.
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Retrospective Analysis of Treatment Pathways in Patients With BRAFV600E-mutant Metastatic Colorectal Carcinoma - MORSECRC
Gerger, A; Eisterer, W; Fuxius, S; Bastian, S; Koeberle, D; Welslau, M; Sa-noyan, DA; Maas, C; Uhlig, J; Fenchel, K; Greil, R; von der Heyde, E; Agocs, GR; Weide, R; Schwager, M; Reichenbach, F; Modest, DP; Fritsch, R.
Anticancer Res. 2022 Oct;42(10):4773-4785. doi: 10.21873/anticanres.15982.
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The influence of pancreatic regression characteristics on outcome of neoadjuvant treated pancreatic cancer in two Austrian university centres.
Neumayer, B; Neureiter, D; Klieser, E; Huemer, F; Weiss, L; Greil, R; Djanani, A; Oberhuber, G; Schlick, K.
Virchows Archiv. 2022; 481(Supplement 1):S135-S135.-34th European Congress of Pathology; 03.-07.09.2022; Basel.
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ESMO 2021-highlights in colorectal cancer.
Weiss, L.
Memo. 2022;15(2):114-116. doi: 10.1007/s12254-022-00808-7. Epub 2022 Apr 28.
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The ABNL-MARRO 001 study: a phase 1-2 study of randomly allocated active myeloid target compound combinations in MDS/MPN overlap syndromes.
Moyo, TK; Mendler, JH; Itzykson, R; Kishtagari, A; Solary, E; Seegmiller, AC; Gerds, AT; Ayers, GD; Dezern, AE; Nazha, A; Valent, P; van de Loosdrecht, AA; Onida, F; Pleyer, L; Cirici, BX; Tibes, R; Geissler, K; Komrokji, RS; Zhang, J; Germing, U; Steensma, DP; Wiseman, DH; Pfeilstoecker, M; Elena, C; Cross, NCP; Luebbert, M; Mesa, RA; Sanz, GF; Platzbecker, U; Patnaik, MM; Padron, E; Santini, V; Fenaux, P; Savona, MR; Kiladjian, JJ; Montalban-Bravo, G.
BMC Cancer. 2022 Sep 24;22(1):1013. doi: 10.1186/s12885-022-10073-w.
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Austrian treatment algorithms in HER2-positive metastatic breast cancer: a 2022 update.
Rinnerthaler, G; Singer, C; Petru, E; Egle, D; Petzer, A; Pluschnig, U; Gampenrieder, SP; Pfeiler, G; Gnant, M; Grunberger, B; Krippl, P; Strasser-Weippl, K; Suppan, C; Brunner, C; Pusch, R; Sandholzer, M; Balic, M; Bartsch, R.
Wien Klin Wochenschr.2022 Oct;134(19-20):683-692. doi: 10.1007/s00508-022-02082-3. Epub 2022 Sep 23.
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Interim analysis (n=150) of the multi-national, prospective, non-interventional ELEANOR study observing real-life extended adjuvant treatment with neratinib in patients with HER2+/ HR+ early breast cancer (eBC).
Harbeck, N; Wrobel, D; Zaiss, M; Guth, D; Distelrath, A; Terhaag, J; Lorenz, A; Bartsch, R; Breitenstein, U; Schwitter, M; Balic, M; Jackisch, C; Muller, V; Rinnerthaler, G; Schmidt, M; Zaman, K; Schinkothe, T; Luftner, D.
ANN ONCOL. 2022; 33: S157-S157.
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First-line treatment of chronic lymphocytic leukemia with ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab: final analysis of the randomized, phase 3 iLLUMINATE trial.
Moreno, C; Greil, R; Demirkan, F; Tedeschi, A; Anz, B; Larratt, L; Simkovic, M; Novak, J; Strugov, V; Gill, D; Gribben, JG; Kwei, K; Dai, S; Hsu, E; Dean, JP; Flinn, IW.
Haematologica.2022 Sep 1;107(9):2108-2120. doi: 10.3324/haematol.2021.279012.
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CIRCULATE Trial: Circulating Tumor DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation (AIO-KRK-0217).
Folprecht, G; Reinacher-Schick, A; Weitz, J; Lugnier, C; Kraeft, AL; Wisser, S; Aust, DE; Weiss, L; von Bubnoff, N; Kramer, M; Thiede, C; Tannapfel, A.
Clin Colorectal Cancer. 2022 Jun;21(2):170-174. doi: 10.1016/j.clcc.2021.09.005. Epub 2021 Sep 15.
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Improved Efficacy of Tafasitamab plus Lenalidomide versus Systemic Therapies for Relapsed/Refractory DLBCL: RE-MIND2, an Observational Retrospective Matched Cohort Study.
Nowakowski, GS; Yoon, DH; Peters, A; Mondello, P; Joffe, E; Fleury, I; Greil, R; Ku, M; Marks, R; Kim, K; Zinzani, PL; Trotman, J; Huang, D; Waltl, EE; Winderlich, M; Kurukulasuriya, NC; Ambarkhane, S; Hess, G; Salles, G.
Clin Cancer Res. 2022 Sep 15;28(18):4003-4017. doi: 10.1158/1078-0432.CCR-21-3648.
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Medication adherence with denosumab in patients with bone metastases from solid tumors treated in routine clinical settings: a retrospective study.
Diel, IJ; Greil, R; Janssen, J; Kluike, CW; Behera, B; Abbasi, A; Seesaghur, A; Kellner, M; Jaeger, C; Bjorklof, K; Tomova, A; Haslbauer, F.
Support Care Cancer. 2022 Nov;30(11):9267-9278. doi: 10.1007/s00520-022-07333-7. Epub 2022 Sep 6.
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Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer.
Singer, CF; Holst, F; Steurer, S; Burandt, EC; Lax, SF; Jakesz, R; Rudas, M; Stoger, H; Greil, R; Sauter, G; Filipits, M; Simon, R; Gnant, M; Abcsg, ABCSG.
Clin Cancer Res. 2022 Sep 15;28(18):4112-4120. doi: 10.1158/1078-0432.CCR-21-4328.
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Assessment of the management of carcinomatous meningitis from breast cancer globally: a study by the Breast International Group Brain Metastasis Task Force.
Razis, E; Escudero, MJ; Palmieri, C; Mueller, V; Bartsch, R; Rossi, G; Gam-penrieder, SP; Kolberg, HC; Zdenkowski, N; Pavic, M; Connolly, RM; Rosset, L; Arcuri, J; Tesch, H; Vallejos, C; Retamales, J; Musolino, A; Del Mastro, L; Christodoulou, C; Aebi, S; Paluch-Shimon, S; Gupta, S; Ohno, S; Macpher-son, I; Ekholm, M; Zaman, K; Vidal, M; Chakiba, C; Fumagalli, D; Thulin, A; Witzel, I; Kotecki, N; Gil-Gil, M; Linderholm, B.
ESMO Open. 2022 Jun;7(3):100483. doi: 10.1016/j.esmoop.2022.100483. Epub 2022 May 13.
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The effect of exercise training on endothelial function in postmenopausal women with breast cancer under aromatase inhibitor therapy.
Mayr, B; Reich, B; Greil, R; Niebauer, J.
Cancer Med. 2022 Dec;11(24):4946-4953. doi: 10.1002/cam4.4833. Epub 2022 May 18.
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DNA methylation profiles differ in responders versus non-responders to anti-PD-1 immune checkpoint inhibitors in patients with advanced and metastatic head and neck squamous cell carcinoma.
Starzer, AM; Heller, G; Tomasich, E; Melchardt, T; Feldmann, K; Hatziioan-nou, T; Traint, S; Minichsdorfer, C; Schwarz-Nemec, U; Nackenhorst, M; Mul-lauer, L; Preusser, M; Berghoff, AS; Fuereder, T.
J Immunother Cancer. 2022 Mar;10(3):e003420. doi: 10.1136/jitc-2021-003420.
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Persistence of ctDNA in Patients with Breast Cancer During Neoadjuvant Treatment Is a Significant Predictor of Poor Tumor Response.
Zhou, Q; Gampenrieder, SP; Frantal, S; Rinnerthaler, G; Singer, CF; Egle, D; Pfeiler, G; Bartsch, R; Wette, V; Pichler, A; Petru, E; Dubsky, PC; Bago-Horvath, Z; Fesl, C; Rudas, M; Ståhlberg, A; Graf, R; Weber, S; Dandachi, N; Filipits, M; Gnant, M; Balic, M; Heitzer, E.
Clin Cancer Res. 2022 Feb 15;28(4):697-707. doi: 10.1158/1078-0432.CCR-21-3231.
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Pembrolizumab alone or with chemotherapy for recurrent or metastatic head and neck squamous cell carcinoma: Health-related quality-of-life results from KEYNOTE-048.
Rischin, D; Harrington, KJ; Greil, R; Soulieres, D; Tahara, M; de Castro, G; Psyrri, A; Brana, I; Neupane, P; Bratland, A; Fuereder, T; Hughes, BGM; Me-sia, R; Ngamphaiboon, N; Rordorf, T; Ishak, WZW; Hong, RL; Mendoza, RG; Jia, LY; Chirovsky, D; Norquist, J; Jin, F; Burtness, B.
Oral Oncol. 2022 May;128:105815. doi: 10.1016/j.oraloncology.2022.105815. Epub 2022 Apr 2.
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Polatuzumab bendamustine and rituximab in untreated chronic lymphocytic leukaemia and small lymphocytic lymphoma (SEQUOIA): a randomised, controlled, phase 3 trial.
Tam, CS; Brown, JR; Kahl, BS; Ghia, P; Giannopoulos, K; Jurczak, W; Simko-vic, M; Shadman, M; Osterborg, A; Laurenti, L; Walker, P; Opat, S; Chan, HR; Ciepluch, H; Greil, R; Tani, M; Trneny, M; Brander, DM; Flinn, IW; Grosicki, S; Verner, E; Tedeschi, A; Li, JY; Tian, T; Zhou, L; Marimpietri, C; Paik, JC; Co-hen, A; Huang, JN; Robak, T; Hillmen, P.
Lancet Oncol. 2022 Aug;23(8):1031-1043. doi: 10.1016/S1470-2045(22)00293-5. Epub 2022 Jul 7.
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Effect of concomitant statin treatment in postmenopausal patients with hormone receptor-positive early-stage breast cancer receiving adjuvant denosumab or placebo: a post hoc analysis of ABCSG-18.
Minichsdorfer, C; Fuereder, T; Leutner, M; Singer, CF; Kacerovsky-Strobl, S; Egle, D; Greil, R; Balic, M; Fitzal, F; Pfeiler, G; Frantal, S; Bartsch, R; Gnant, M.
ESMO Open. 2022 Apr;7(2):100426. doi: 10.1016/j.esmoop.2022.100426. Epub 2022 Mar 22.
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Adverse Events in 1406 Patients Receiving 13,780 Cycles of Azacitidine within the Austrian Registry of Hypomethylating Agents-A Prospective Cohort Study of the AGMT Study-Group.
Leisch, M; Pfeilstocker, M; Stauder, R; Heibl, S; Sill, H; Girschikofsky, M; Stampfl-Mattersberger, M; Tinchon, C; Hartmann, B; Petzer, A; Schreder, M; Kiesl, D; Vallet, S; Egle, A; Melchardt, T; Piringer, G; Zebisch, A; Machherndl-Spandl, S; Wolf, D; Keil, F; Drost, M; Greil, R; Pleyer, L.
Cancers (Basel). 2022 May 17;14(10):2459. doi: 10.3390/cancers14102459.
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Pathologic complete response (pCR) to neoadjuvant treatment with or without atezolizumab in triple-negative, early high-risk and locally advan-ced breast cancer: NeoTRIP Michelangelo randomized study.
Gianni, L; Huang, CS; Egle, D; Bermejo, B; Zamagni, C; Thill, M; Anton, A; Zambelli, S; Bianchini, G; Russo, S; Ciruelos, EM; Greil, R; Semiglazov, V; Colleoni, M; Kelly, C; Mariani, G; Del Mastro, L; Maffeis, I; Valagussa, P; Viale, G.
Ann Oncol. 2022 May;33(5):534-543. doi: 10.1016/j.annonc.2022.02.004. E-pub 2022 Feb 17.
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Pembrolizumab Alone or With Chemotherapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma in KEYNOTE-048: Subgroup Analysis by Programmed Death Ligand-1 Combined Positive Score.
Burtness, B; Rischin, D; Greil, R; Soulieres, D; Tahara, M; de Castro, G; Psyr-ri, A; Brana, I; Baste, N; Neupane, P; Bratland, A; Fuereder, T; Hughes, BGM; Mesia, R; Ngamphaiboon, N; Rordorf, T; Ishak, WZW; Ge, J; Swaby, RF; Gu-muscu, B; Harrington, K.
J Clin Oncol. 2022 Jul 20;40(21):2321-2332. doi: 10.1200/JCO.21.02198. E-pub 2022 Mar 25.
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Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial.
Ader, F; Bouscambert-Duchamp, M; Hites, M; Peiffer-Smadja, N; Poissy, J; Belhadi, D; Diallo, A; Lê, MP; Peytavin, G; Staub, T; Greil, R; Guedj, J; Paiva, JA; Costagliola, D; Yazdanpanah, Y; Burdet, C; Mentré, F.
Lancet Infect Dis. 2022 Feb;22(2):209-221. doi: 10.1016/S1473-3099(21)00485-0. Epub 2021 Sep 14.
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Low HER2 expression does not influence prognosis in metastatic triple-negative breast cancer: Results from an international, multicenter analysis coordinated by the Austrian Group Medical Tumor Therapy (AGMT).
Gampenrieder, SP; Dezentje, V; Lambertini, M; de Nonneville, A; Marhold, M; Le Du, F; Serrano, CS; Costa, DA; Blondeaux, E; Del Mastro, L; Bertucci, F; Goncal-ves, A; Bartsch, R; Deleuze, A; Salgado, AC; Vitorino, M; Tinchon, C; Pecen, L; Rinnerthaler, G; Greil, R.
ANN ONCOL. 2022; 33: S208-S208.
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Endothelin-1 genetic polymorphism (SNP rs5370-TT) fails to predict re-sistance to bevacizumab in metastatic breast cancer patients treated within the TANIA phase III trial
Gampenrieder, SP; Steiner, M; Hufnagl, C; Hackl, H; Rinnerthaler, G; Westphal, T; Huemer, F; Monzo-Fuentes, C; Morre, P; Hauser-Kronberger, C; Greil, R.
ANN ONCOL. 2022; 33: S141-S141.
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Encorafenib and cetuximab in patients with metastatic, BRAF V600E-mutated, colorectal cancer: Update on the first real-world study in Germany and Austria BERING CRC
von der Heyde, E; Burkle, D; Forstbauer, H; Hubner, G; Schmidt, B; Schroder, J; Distelrath, A; Wierecky, J; Stubs, P; Kisro, J; Welslau, M; Muller-Huesmann, H; Gohler, T; Krammer-Steiner, B; Schwaner, I; Hering-Schubert, C; Gerger, A; Greil, R; Jacobasch, L; Reichenbach, F; Stintzing, S; Prager, G.
ANN ONCOL. 2022; 33: S248-S248.
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Updated Results of Tucatinib versus Placebo in Combination with Trastuzu-mab and Capecitabine in Patients with pretreated metastatic HER2-positive Breast Cancer with CNS Metastases (HER2CLIMB).
Greil, R; Lin, UN; Murthy, KR; Abramson, V; Anders, C; Bachelot, T; Bedard, LP; Borges, V; Cameron, D; Carey, L; Chien, JA; Curigliano, G; DiGiovanna, PM; Gel-mon, K; Hortobagyi, G; Hurvitz, S; Krop, I; Loi, S; Loibl, S; Mueller, V; Oliveira, M; Paplomata, E; Pegram, M; Slamon, D; Zelnak, A; Ramos, J; Feng, W; Winer, E.
Geburtshilfe Frauenheilkd 2022; 82(04): e4-e5. DOI: 10.1055/s-0042-1746156
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REACH AUT: Efficacy and safety of first-line (1L) ribociclib (RIB) plus en-docrine therapy (ET) in HR+, HER2-metastatic breast cancer (MBC) from a real-world (RW) study: 3rd interim analysis.
Singer, CF; Egle, D; Greil, R; Petru, E; Ohler, L; Balic, M; Tinchon, C; Pfeiler, G; Marhold, M; Brunner, C; Haider, K; Galid, A; Pluschnig, U; Haslbauer, F; Hubalek, M; Redl, A; Flatschacher, J; Uthman, S; Mraz, B; Bartsch, R.
ANN ONCOL. 2022; 33: S217-S217.
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Polatuzumab Vedotin plus Rituximab, Cyclophosphamide, Doxorubicin and Prednisone (pola-R-CHP) Versus Rituximab, Cyclophosphamide, Doxorubi-cin, Vincristine and Prednisone (R-CHOP) Therapy in Patients with Previ-ously Untreated Diffuse Large B-Cell Lymphoma: Results from the Phase III POLARIX Study.
Tilly, H; Morschhauser, F; Sehn, LH; Friedberg, JW; Trneny, M; Sharman, JP; Her-baux, C; Burke, JM; Matasar, M; Rai, S; Izutsu, K; Mehta-Shah, N; Oberic, L; Chauchet, A; Jurczak, W; Song, YQ; Greil, R; Mykhalska, L; Miguel, J; Burgues, B; Cheung, MC; Pinto, A; Shin, HJ; Hapgood, G; Munhoz, E; Abrisqueta, P; Gau, JP; Hirata, J; Jiang, YW; Yan, M; Lee, C; Flowers, C; Salles, G; Collins, G.
BRIT J HAEMATOL. 2022; 197: 14-16.
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Phase 1b study of tarlatamab, a half-life extended bispecific T-cell engager (HLE BiTE immune therapy) targeting DLL3, in de novo or treatment emergent neuroendocrine prostate cancer (NEPC).
Aggarwal, RR; Rottey, S; Aparicio, A; Greil, R; Reimers, MA; Sandhu, SK; Zhang, YR; Salvati, M; Sadraei, NH.
J CLIN ONCOL. 2022; 40(6): DOI: 10.1200/JCO.2022.40.6_suppl.TPS197 Journal of Clinical Oncology 40, no. 6_suppl
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Detecting Bacterial-Human Lateral Gene Transfer in Chronic Lymphocy-tic Leukemia.
Akimova, E; Gassner, FJ; Greil, R; Zaborsky, N; Geisberger, R.
Int J Mol Sci. 2022 Jan 20;23(3):1094. doi: 10.3390/ijms23031094.
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Second-Line Tisagenlecleucel or Standard Care in Aggressive B-Cell Lymphoma.
Bishop, MR; Dickinson, M; Purtill, D; Barba, P; Santoro, A; Hamad, N; Kato, K; Sureda, A; Greil, R; Thieblemont, C; Morschhauser, F; Janz, M; Flinn, I; Rabitsch, W; Kwong, YL; Kersten, MJ; Minnema, MC; Holte, H; Chan, EHL; Martinez-Lopez, J; Muller, AMS; Maziarz, RT; McGuirk, JP; Bachy, E; Le Gouill, S; Dreyling, M; Harigae, H; Bond, D; Andreadis, C; McSweeney, P; Kharfan-Dabaja, M; Newsome, S; Degtyarev, E; Awasthi, R; del Corral, C; Andreola, G; Masood, A; Schuster, SJ; Jager, U; Borchmann, P; Westin, JR.
N Engl J Med. 2022 Feb 17;386(7):629-639. doi: 10.1056/NEJMoa2116596. Epub 2021 Dec 14.
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Updated Austrian treatment algorithm in HER2+ metastatic breast cancer.
Bartsch, R; Gampenrieder, SP; Rinnerthaler, G; Petru, E; Egle, D; Petzer, A; Balic, M; Pluschnig, U; Sliwa, T; Singer, C.
Wien Klin Wochenschr. 2022 Jan;134(1-2):63-72. doi: 10.1007/s00508-021-01987-9. Epub 2022 Jan 28.
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Accelerating clinical trial implementation in the context of the COVID-19 pandemic: challenges, lessons learned and recommendations from Dis-CoVeRy and the EU-SolidAct EU response group.
Diallo, A; Troseid, M; Simensen, VC; Boston, A; Demotes, J; Olsen, IC; Chung, F; Paiva, JA; Hites, M; Ader, F; Arribas, JR; Baratt-Due, A; Melien, O; Tacconelli, E; Staub, T; Greil, R; Tsiodras, S; Briel, M; Esperou, H; Mentre, F; Eustace, J; Saillard, J; Delmas, C; LeMestre, S; Dumousseaux, M; Costaglio-la, D; Rottingen, JA; Yazdanpanah, Y.
Clin Microbiol Infect. 2022 Jan;28(1):1-5. doi: 10.1016/j.cmi.2021.10.011. E-pub 2021 Nov 8.
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Adjuvant Palbociclib for Early Breast Cancer: The PALLAS Trial Results (ABCSG-42/AFT-05/BIG-14-03).
Gnant, M; Dueck, AC; Frantal, S; Martin, M; Burstein, HJ; Greil, R; Fox, P; Wolff, AC; Chan, A; Winer, EP; Pfeiler, G; Miller, KD; Colleoni, M; Suga, JM; Rubovsky, G; Bliss, JM; Mayer, IA; Singer, CF; Nowecki, Z; Hahn, O; Thom-son, J; Wolmark, N; Amillano, K; Rugo, HS; Steger, GG; Hernando Fernández de Aránguiz, B; Haddad, TC; Perelló, A; Bellet, M; Fohler, H; Metzger Filho, O; Jallitsch-Halper, A; Solomon, K; Schurmans, C; Theall, KP; Lu, DR; Tenner, K; Fesl, C; DeMichele, A; Mayer, EL.
J Clin Oncol. 2022 Jan 20;40(3):282-293. doi: 10.1200/JCO.21.02554. Epub 2021 Dec 7.
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A Randomized Phase II Study of Anti-CSF1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple-Negative Breast Cancer.
Kuemmel, S; Campone, M; Loirat, D; Lopez, RL; Beck, JT; De Laurentiis, M; Im, SA; Kim, SB; Kwong, A; Steger, GG; Adelantado, EZ; Duhoux, FP; Greil, R; Kuter, I; Lu, YS; Tibau, A; Özgüroğlu, M; Scholz, CW; Singer, CF; Vega, E; Wimberger, P; Zamagni, C; Couillebault, XM; Fan, L; Guerreiro, N; Mataraza, J; Sand-Dejmek, J; Chan, A.
Clin Cancer Res. 2022 Jan 1;28(1):106-115. doi: 10.1158/1078-0432.CCR-20-3955. Epub 2021 Oct 6.
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Checkpoint inhibitors in metastatic gastric and GEJ cancer: a multi-institutional retrospective analysis of real-world data in a Western cohort.
Schlintl, V; Huemer, F; Rinnerthaler, G; Melchardt, T; Winder, T; Reimann, P; Riedl, J; Amann, A; Eisterer, W; Romeder, F; Piringer, G; Ilhan-Mutlu, A; Wöll, E; Greil, R; Weiss, L.
BMC Cancer. 2022 Jan 10;22(1):51. doi: 10.1186/s12885-021-09115-6.
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Polatuzumab Vedotin in Previously Untreated Diffuse Large B-Cell Lym-phoma.
Tilly, H; Morschhauser, F; Sehn, LH; Friedberg, JW; Trneny, M; Sharman, JP; Herbaux, C; Burke, JM; Matasar, M; Rai, S; Izutsu, K; Mehta-Shah, N; Oberic, L; Chauchet, A; Jurczak, W; Song, YQ; Greil, R; Mykhalska, L; Bergua-Burgues, JM; Cheung, MC; Pinto, A; Shin, HJ; Hapgood, G; Munhoz, E; Ab-risqueta, P; Gau, JP; Hirata, J; Jiang, YW; Yan, M; Lee, C; Flowers, CR; Sal-les, G.
N Engl J Med. 2022 Jan 27;386(4):351-363. doi: 10.1056/NEJMoa2115304. Epub 2021 Dec 14.
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Evaluating a Targeted Cancer Therapy Approach Mediated by RNA.
Woess, K; Sun, Y; Morio, H; Stierschneider, A; Kaufmann, A; Hainzl, S; Tratt-ner, L; Kocher, T; Tockner, B; Leb-Reichl, V; Steiner, M; Brachtl, G; South, AP; Bauer, JW; Reichelt, J; Furihata, T; Wally, V; Koller, U; Piñón Hofbauer, J; Guttmann-Gruber, C.
Int J Mol Sci. 2022 Jan 5;23(1):575. doi: 10.3390/ijms23010575.
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Challenges in measuring phosphoproteomics with CyTOF in CLL.
Markus Steiner, Daniela Asslaber, Nadja Zaborsky, Alexander Egle, Richard Greil.
5th German Mass Cytometry User Forum; 20.01.-21.01.2022; Online.
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Kindlin-3 maintains marginal zone B cells but confines follicular B cell activation and differentiation.
Härzschel A, Li L, Krenn PW, Szenes-Nagy E, Andrieux G, Bayer E, Pfei-fer D, Polcik L, Denk U, Höpner JP, Karabatak E, Danner DJ, Tangermann S, Kenner L, Jumaa H, Greil R, Börries M, Ruppert R, Maity PC, Hartmann TN.
J Leukoc Biol. 2021 Dec 10. doi: 10.1002/JLB.1HI0621-313R. Online ahead of print. PMID: 34888947
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Landscape of HER2-low metastatic breast cancer (MBC): results from the Austrian AGMT_MBC-Registry.
Gampenrieder, SP; Rinnerthaler, G; Tinchon, C; Petzer, A; Balic, M; Heibl, S; Schmitt, C; Zabernigg, AF; Egle, D; Sandholzer, M; Singer, CF; Roitner, F; Hager, C; Andel, J; Hubalek, M; Knauer, M; Greil, R.
Breast Cancer Res. 2021 Dec 14;23(1):112. doi: 10.1186/s13058-021-01492-x.
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Persistence of ctDNA in breast cancer patients during neoadjuvant treatment is a significant predictor of poor tumour response.
Zhou, Q; Gampenrieder, SP; Frantal, S; Rinnerthaler, G; Singer, CF; Egle, D; Pfeiler, G; Bartsch, R; Wette, V; Pichler, A; Petru, E; Dubsky, PC; Bago-Horvath, Z; Fesl, C; Rudas, M; Ståhlberg, A; Graf, R; Weber, S; Dandachi, N; Filipits, M; Gnant, M; Balic, M; Heitzer, E.
Clin Cancer Res. 2021 Dec 3. doi: 10.1158/1078-0432.CCR-21-3231. On-line ahead of print.
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Sex-Based Clinical Outcome in Advanced NSCLC Patients Undergoing PD-1/PD-L1 Inhibitor Therapy-A Retrospective Bi-Centric Cohort Study.
Lang, D; Brauner, A; Huemer, F; Rinnerthaler, G; Horner, A; Wass, R; Brehm, E; Kaiser, B; Greil, R; Lamprecht, B.
Cancers (Basel). 2021 Dec 24;14(1):93. doi: 10.3390/cancers14010093.
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Scalable Enrichment of Immunomodulatory Human Acute Myeloid Leukemia Cell Line-Derived Extracellular Vesicles.
Binder, HM; Maeding, N; Wolf, M; Cronemberger Andrade, A; Vari, B; Krisch, L; Gomes, FG; Blöchl, C; Muigg, K; Poupardin, R; Raninger, AM; Heuser, T; Obermayer, A; Ebner-Peking, P; Pleyer, L; Greil, R; Huber, CG; Schallmoser, K; Strunk, D.
Cells. 2021 Nov 26;10(12):3321. doi: 10.3390/cells10123321.
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Position Paper on the Value of Extended Adjuvant Therapy with Neratinib for Early HER2+/HR+ Breast Cancer.
Balic, M; Rinnerthaler, G; Bartsch, R.
Breast Care (Basel). 2021 Dec;16(6):664-676. doi: 10.1159/000518696. Epub 2021 Oct 29.
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Leveraging immune memory against measles virus as an antitumor strategy in a preclinical model of aggressive squamous cell carcinoma.
Leb-Reichl, VM; Kienzl, M; Kaufmann, A; Stoecklinger, A; Tockner, B; Kitzmueller, S; Zaborsky, N; Steiner, M; Brachtl, G; Trattner, L; Kreide-weiss, P; Reinsch, C; Panzner, S; Greil, R; Strunk, D; Bauer, JW; Gratz, IK; Guttmann-Gruber, C; Hofbauer, JP.
J Immunother Cancer. 2021 Oct;9(10):e002170. doi: 10.1136/jitc-2020-002170.
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Casein Kinase 1D Encodes a Novel Drug Target in Hedgehog-GLI-Driven Cancers and Tumor-Initiating Cells Resistant to SMO Inhibition.
Peer, E; Aichberger, SK; Vilotic, F; Gruber, W; Parigger, T; Grund-Groschke, S; Elmer, DP; Rathje, F; Ramspacher, A; Zaja, M; Michel, S; Hamm, S; Aberger, F.
Cancers (Basel). 2021 Aug 23;13(16):4227. doi: 10.3390/cancers13164227.
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CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues.
Yu, XB; Munoz-Sagredo, L; Streule, K; Muschong, P; Bayer, E; Walter, RJ; Gutjahr, JC; Greil, R; Conch, ML; Muller-Tidow, C; Hartmann, TN; Orian-Rousseau, V.
Blood. 2021 Sep 23;138(12):1067-1080. doi: 10.1182/blood.2020006343.
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The Role of Neutrophilic Granulocytes in Philadelphia Chromosome Negative Myeloproliferative Neoplasms.
Kiem, D; Wagner, S; Magnes, T; Egle, A; Greil, R; Melchardt, T.
Int J Mol Sci. 2021 Sep 3;22(17):9555. doi: 10.3390/ijms22179555.
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Genomic and Transcriptomic Analyses of Breast Cancer Primaries and Matched Metastases in AURORA, the Breast International Group (BIG) Molecular Screening Initiative.
Aftimos, P; Oliveira, M; Irrthum, A; Fumagalli, D; Sotiriou, C; Gal-Yam, EN; Robson, ME; Ndozeng, J; Di Leo, A; Ciruelos, EM; de Azambuja, E; Viale, G; Scheepers, ED; Curigliano, G; Bliss, JM; Reis, JS; Colleoni, M; Balic, M; Cardoso, F; Albanell, J; Duhem, C; Marreaud, S; Romagnoli, D; Rojas, B; Gombos, A; Wildiers, H; Guerrero-Zotano, A; Hall, P; Bonetti, A; Larsson, KF; Degiorgis, M; Khodaverdi, S; Greil, R; Sverrisdottir, A; Paoli, M; Seyll, E; Loibl, S; Linderholm, B; Zoppoli, G; Davidson, NE; Johannsson, OT; Bedard, PL; Loi, S; Knox, S; Cameron, DA; Harbeck, N; Montoya, ML; Brandao, M; Vingiani, A; Caballero, C; Hilbers, FS; Yates, LR; Benelli, M; Venet, D; Piccart, MJ.
Cancer Discov. 2021 Nov;11(11):2796-2811. doi: 10.1158/2159-8290.CD-20-1647. Epub 2021 Jun 28.
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ESR1, PGR, ERBB2, and MKi67 mRNA expression in postmenopausal women with hormone receptor-positive early breast cancer: results from ABCSG Trial 6.
Filipits, M; Rudas, M; Singer, CF; Fitzal, F; Bago-Horvath, Z; Greil, R; Balic, M; Lax, SF; Halper, S; Hulla, W; Wu, NC; Liu, X; Weidler, J; Bates, M; Hlauschek, D; Gnant, M; Dubsky, P.
ESMO Open. 2021 Aug;6(4):100228. doi: 10.1016/j.esmoop.2021.100228. Epub 2021 Aug 7.
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The OncoMasTR Test Predicts Distant Recurrence in Estrogen Receptor-Positive, HER2-Negative Early-Stage Breast Cancer: A Vali-dation Study in ABCSG Trial 8.
Filipits, M; Rudas, M; Kainz, V; Singer, CF; Fitzal, F; Bago-Horvath, Z; Greil, R; Balic, M; Regitnig, P; Halper, S; Hulla, W; Egle, D; Barron, S; Loughman, T; OxxxLeary, D; Gallagher, WM; Hlauschek, D; Gnant, M; Dubsky, P.
Clin Cancer Res. 2021 Nov 1;27(21):5931-5938. doi: 10.1158/1078-0432.CCR-21-1023. Epub 2021 Aug 11.
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Non-pegylated Liposomal Doxorubicin as Palliative Chemotherapy in pre-Treated Advanced Pancreatic Cancer: A Retrospective Analysis of Twenty-Eight Patients.
Schlick, K; Kiem, D; Huemer, F; Neureiter, D; Weiss, L; Greil, R.
Technol Cancer Res Treat. Jan-Dec 2021;20:15330338211042139. doi: 10.1177/15330338211042139.
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A POLE Splice Site Deletion Detected in a Patient with Biclonal CLL and Prostate Cancer: A Case Report.
Steiner, M; Gassner, FJ; Parigger, T; Neureiter, D; Egle, A; Geisberger, R; Greil, R; Zaborsky, N.
Int J Mol Sci. 2021 Aug 30;22(17):9410. doi: 10.3390/ijms22179410.
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CAR T-Cell Therapy in Hematological Malignancies.
Haslauer, T; Greil, R; Zaborsky, N; Geisberger, R.
Int J Mol Sci. 2021 Aug 20;22(16):8996. doi: 10.3390/ijms22168996.
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Evidence for Non-Cancer-Specific T Cell Exhaustion in the Tcl1 Mouse Model for Chronic Lymphocytic Leukemia.
Parigger, T; Gassner, FJ; Scherhaufl, C; Abu Bakar, A; Hopner, JP; Hodlmoser, A; Steiner, M; Catakovic, K; Geisberger, R; Greil, R; Zaborsky, N.
Int J Mol Sci. 2021 Jun 22;22(13):6648. doi: 10.3390/ijms22136648.
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AID Contributes to Accelerated Disease Progression in the TCL1 Mouse Transplant Model for CLL.
Schubert, M; Gassner, FJ; Huemer, M; Hopner, JP; Akimova, E; Steiner, M; Egle, A; Greil, R; Zaborsky, N; Geisberger, R.
Cancers (Basel). 2021 May 26;13(11):2619. doi: 10.3390/cancers13112619.
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Re-Sensitizing Tumor Cells to Cancer Drugs with Epigenetic Regulators.
Rauscher, S; Greil, R; Geisberger, R.
Curr Cancer Drug Targets. 2021;21(4):353-359. doi: 10.2174/1568009620666210108102723.
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Duration of Adjuvant Aromatase-Inhibitor Therapy in Postmenopausal Breast Cancer.
Gnant, M; Fitzal, F; Rinnerthaler, G; Steger, GG; Greil-Ressler, S; Balic, M; Heck, D; Jakesz, R; Thaler, J; Egle, D; Manfreda, D; Bjelic-Radisic, V; Wieder, U; Singer, CF; Melbinger-Zeinitzer, E; Haslbauer, F; Sevelda, P; Trapl, H; Wette, V; Wimmer, K; Gampenrieder, SP; Bartsch, R; Kacerovsky-Strobl, S; Suppan, C; Brunner, C; Deutschmann, C; Soelkner, L; Fesl, C; Greil, R.
N Engl J Med. 2021 Jul 29;385(5):395-405. doi: 10.1056/NEJMoa2104162.
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Measurable residual disease in chronic lymphocytic leukemia: expert re-view and consensus recommendations.
Wierda, WG; Rawstron, A; Cymbalista, F; Badoux, X; Rossi, D; Brown, JR; Egle, A; Abello, V; Ceballos, EC; Herishanu, Y; Mulligan, SP; Niemann, CU; Diong, CP; Soysal, T; Suzuki, R; Tran, HTT; Wu, SJ; Owen, C; Stilgenbauer, S; Ghia, P; Hillmen, P.
Leukemia. 2021 Jun 24. doi: 10.1038/s41375-021-01241-1. Online ahead of print.
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Evaluation of circulating cell-free KRAS mutational status as a molecular monitoring tool in patients with pancreatic cancer.
Schlick, K; Markus, S; Huemer, F; Ratzinger, L; Zaborsky, N; Clemens, H; Neureiter, D; Neumayer, B; Beate, AS; Florian, S; Martin, V; Grundbichler, M; Weiss, L; Melchardt, T; Greil, R; Egle, A.
Pancreatology. 2021 Sep 8;S1424-3903(21)00568-8. doi: 10.1016/j.pan.2021.09.004. Online ahead of print.
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Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus in PKP3 in lung epithelial cells.
Schamschula, E; Lahnsteiner, A; Assenov, Y; Hagmann, W; Zaborsky, N; Wiederstein, M; Strobl, A; Stanke, F; Muley, T; Plass, C; Tummler, B; Risch, A.
Epigenetics. 2021 Aug 20;1-24. doi: 10.1080/15592294.2021.1959976. Online ahead of print.
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Influence of Height on Risk and Outcome of Patients with Early Breast Cancer: A Pooled Analysis of 4,925 Patients from 5 Randomized Trials of the Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Gampenrieder, SP; Pircher, M; Fesl, C; Rinnerthaler, G; Mlineritsch, B; Greil-Ressler, S; Steger, GG; Sagaster, V; Fitzal, F; Exner, R; Devyatko, Y; Balic, M; Stoger, H; Suppan, C; Bauernhofer, T; Singer, CF; Pfeiler, G; Seifert, M; Helfgott, R; Heck, D; Rumpold, H; Kwasny, W; Wieder, U; Gnant, M; Greil, R.
BREAST CARE. 2021; https://doi.org/10.1159/000516157
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Expert Discussion: Immunotherapy in Breast Cancer - Ready for Prime Time?
Rinnerthaler, G; Müller, V; Balic, M; Zaman, K; Dieci, MV.
Breast Care (Basel). 2021 Apr;16(2):188-191. doi: 10.1159/000515746. Epub 2021 Mar 26.
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Pretreatment with ibrutinib reduces cytokine secretion and limits the risk of obinutuzumab-induced infusion-related reactions in patients with CLL: analysis from the iLLUMINATE study.
Greil, R; Tedeschi, A; Moreno, C; Anz, B; Larratt, L; Simkovic, M; Gill, D; Gribben, JG; Flinn, IW; Wang, ZY; Cheung, LWK; Nguyen, AN; Zhou, C; Sty-les, L; Demirkan, F.
Ann Hematol. 2021 Jul;100(7):1733-1742. doi: 10.1007/s00277-021-04536-6. Epub 2021 May 20.
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Randomized Phase III Study of FOLFOX Alone or With Pegilodecakin as Second-Line Therapy in Patients With Metastatic Pancreatic Cancer That Progressed After Gemcitabine (SEQUOIA).
Hecht, JR; Lonardi, S; Bendell, J; Sim, HW; Macarulla, T; Lopez, CD; Van Cutsem, E; Martin, AJM; Park, JO; Greil, R; Wang, H; Hozak, RR; Gueorguieva, I; Lin, Y; Rao, S; Ryoo, BY.
J Clin Oncol. 2021 Apr 1;39(10):1108-1118. doi: 10.1200/JCO.20.02232. Epub 2021 Feb 8.
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Incidence of central nervous system relapses in patients with DLBCL treated with lenalidomide as maintenance after R-CHOP.
Bernard, S; Ghesquieres, H; Casasnovas, RO; Griolet, S; da Silva, MG; Feugier, P; Morschhauser, F; Trotman, J; Renaud, L; Greil, R; Garcia-Sancho, AM; Grosicki, S; van Eygen, K; Copie-Bergman, C; Haioun, C; Thieblemont, C.
Blood Adv. 2021 Aug 10;5(15):2965-2968. doi: 10.1182/bloodadvances.2021004766.
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The Effect of SF3B1 Mutation on the DNA Damage Response and Nonsense-Mediated mRNA Decay in Cancer.
Leeksma AC, Derks IAM, Kasem MH, Kilic E, de Klein A, Jager MJ, van de Loosdrecht AA, Jansen JH, Navrkalova V, Faber LM, Zaborsky N, Egle A, Zenz T, Pospisilova S, Abdel-Wahab O, Kater AP, Eldering E.
Front Oncol. 2021 Jan 29;10:609409. doi: 10.3389/fonc.2020.609409. eCollection 2020.
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Sustained response to brigatinib in a patient with refractory metastatic pheochromocytoma harboring R1192P anaplastic lymphoma kinase mutation: a case report from the Austrian Group Medical Tumor Therapy next-generation sequencing registry and discussion of the literature.
Heregger, R; Huemer, F; Hutarew, G; Hecht, S; Cheveresan, L; Kotzot, D; Schamschula, E; Rinnerthaler, G; Melchardt, T; Weiss, L; Greil, R.
ESMO Open. 2021 Aug;6(4):100233. doi: 10.1016/j.esmoop.2021.100233. Epub 2021 Aug 7.
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Docetaxel, cisplatin and 5-FU compared with docetaxel, cisplatin and cetuximab as induction chemotherapy in advanced squamous cell carcinoma of the head and neck: Results of a randomised phase II AGMT trial.
Keil, F; Hartl, M; Altorjai, G; Berghold, A; Riedl, R; Pecherstorfer, M; Mayrbäurl, B; De Vries, A; Schuster, J; Hackl, J; Füreder, T; Melchardt, T; Burian, M; Greil, R.
Eur J Cancer. 2021 Jul;151:201-210. doi: 10.1016/j.ejca.2021.03.051. Epub 2021 May 19.
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Two Cases of Pancytopenia with Coombs-Negative Hemolytic Anemia af-ter Chimeric Antigen Receptor T-Cell Therapy.
Kiem, D; Leisch, M; Neureiter, D; Haslauer, T; Egle, A; Melchardt, T; Topp, MS; Greil, R.
Int J Mol Sci. 2021 May 21;22(11):5449. doi: 10.3390/ijms22115449.
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Deregulated glutamate to pro-collagen conversion is associated with adverse outcome in lung cancer and may be targeted by renin-angiotensin-aldosterone system (RAS) inhibition.
Kocher, F; Tymoszuk, P; Amann, A; Sprung, S; Salcher, S; Daum, S; Haybaeck, J; Rinnerthaler, G; Huemer, F; Kauffmann-Guerrero, D; Tufman, A; Seeber, A; Wolf, D; Pircher, A.
Lung Cancer. 2021 Sep;159:84-95. doi: 10.1016/j.lungcan.2021.06.020. Epub 2021 Jul 16.
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Postoperative chemoradiotherapy with cisplatin is superior to radioimmunotherapy with cetuximab and radiotherapy alone : Analysis of the Austrian head and neck cancer registry of the AGMT.
Magnes, T; Wagner, SM; Melchardt, T; Weiss, L; Rinnerthaler, G; Huemer, F; Kopp, M; Gampenrieder, SP; Mayrbäurl, B; Füreder, T; Lenger, D; Andel, J; Egle, A; Greil, R.
Wien Klin Wochenschr. 2021 Sep 15. doi: 10.1007/s00508-021-01939-3. Online ahead of print.
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Selective Activation of CNS and Reference PPARGC1A Promoters Is As-sociated with Distinct Gene Programs Relevant for Neurodegenerative Diseases.
Kwik, M; Hainzl, S; Oppelt, J; Tichy, B; Koller, U; Bernardinelli, E; Steiner, M; Zara, G; Nofziger, C; Weis, S; Paulmichl, M; Dossena, S; Patsch, W; Soyal, SM.
Int J Mol Sci. 2021 Mar 24;22(7):3296. doi: 10.3390/ijms22073296.
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Prognostic and Predictive Factors in Advanced Head and Neck Squamous Cell Carcinoma.
Magnes, T; Wagner, S; Kiem, D; Weiss, L; Rinnerthaler, G; Greil, R; Melchardt, T.
Int J Mol Sci. 2021 May 7;22(9):4981. doi: 10.3390/ijms22094981.
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SAMHD1 restrains aberrant nucleotide insertions at repair junctions generated by DNA end joining.
Akimova, E; Gassner, FJ; Schubert, M; Rebhandl, S; Arzt, C; Rauscher, S; Tober, V; Zaborsky, N; Greil, R; Geisberger, R.
Nucleic Acids Res. 2021 Mar 18;49(5):2598-2608. doi: 10.1093/nar/gkab051.
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Conventional versus reverse sequence of neoadjuvant epirubicin/cyclophosphamide and docetaxel: sequencing results from ABCSG-34.
Bartsch, R; Singer, CF; Pfeiler, G; Hubalek, M; Stoeger, H; Pichler, A; Petru, E; Bjelic-Radisic, V; Greil, R; Rudas, M; Muy-Kheng, TM; Wette, V; Petzer, AL; Sevelda, P; Egle, D; Dubsky, PC; Filipits, M; Fitzal, F; Exner, R; Jakesz, R; Balic, M; Tinchon, C; Bago-Horvath, Z; Frantal, S; Gnant, M.
Br J Cancer. 2021 May;124(11):1795-1802. doi: 10.1038/s41416-021-01284-2. Epub 2021 Mar 24.
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Austrian recommendations for the management of essential thrombocythemia.
Buxhofer-Ausch, V; Heibl, S; Sliwa, T; Beham-Schmid, C; Wolf, D; Geissler, K; Krauth, MT; Krippl, P; Petzer, A; Wolfler, A; Melchardt, T; Gisslinger, H.
Wien Klin Wochenschr. 2021 Jan;133(1-2):52-61. doi: 10.1007/s00508-020-01761-3. Epub 2020 Nov 19.
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Cytotoxic constituents and a new hydroxycinnamic acid derivative from Leontodon saxatilis (Asteraceae, Cichorieae).
Cicek, SS; Willer, J; Preziuso, F; Sonnichsen, F; Greil, R; Girreser, U; Zidorn, C; Johrer, K.
RSC ADV. 2021; 11(18): 10489-10496. DOI: 10.1039/d0ra10973h
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A clinical validation study of MammaPrint in hormone receptor-positive breast cancer from the Austrian Breast and Colorectal Cancer Study Group 8 (ABCSG-8) biomarker cohort.
Dubsky, P; Vant Veer, L; Gnant, M; Rudas, M; Bago-Horvath, Z; Greil, R; Lujinovic, E; Buresch, J; Rinnerthaler, G; Hulla, W; Moinfar, F; Egle, D; Herz, W; Dreezen, C; Frantal, S; Filipits, M.
ESMO Open. 2021 Feb;6(1):100006. doi: 10.1016/j.esmoop.2020.100006. Epub 2020 Dec 31.
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RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia.
Gassner, FJ; Zaborsky, N; Buchumenski, I; Levanon, EY; Gatterbauer, M; Schubert, M; Rauscher, S; Hebenstreit, D; Nadeu, F; Campo, E; Egle, A; Greil, R; Geisberger, R.
Leukemia. 2021 Apr;35(4):1053-1063. doi: 10.1038/s41375-020-0995-6. Epub 2020 Jul 30.
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Vinorelbine as substitute for vincristine in patients with diffuse large B cell lymphoma and vincristine-induced neuropathy.
Hatzl, S; Posch, F; Rezai, A; Gornicec, M; Beham-Schmid, C; Magnes, T; Wangner, S; Deutsch, A; Greinix, H; Uhl, B; Prochazka, KT; Egle, A; Greil, R; Melchardt, T; Linkesch, W; Schulz, E; Neumeister, P.
Support Care Cancer. 2021 Feb 24. doi: 10.1007/s00520-021-06059-2. Online ahead of print.
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miRNA-Based Therapeutics in the Era of Immune-Checkpoint Inhibitors.
Huemer, F; Leisch, M; Geisberger, R; Zaborsky, N; Greil, R.
Pharmaceuticals (Basel). 2021 Jan 26;14(2):89. doi: 10.3390/ph14020089.
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Results of a hospitalization policy of asymptomatic and pre-symptomatic COVID-19-positive long-term care facility residents in the province of Salzburg-a report from the AGMT COVID-19 Registry.
Huemer, F; Rinnerthaler, G; Jörg, B; Morre, P; Stegbuchner, B; Proksch, E; Fleimisch, S; Oberkofler, H; Kremser, I; Greil, R; Egle, A.
Geroscience. 2021 Apr 10;1-21. doi: 10.1007/s11357-021-00352-y. Online ahead of print.
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Spatial Heterogeneity in Large Resected Diffuse Large B-Cell Lymphoma Bulks Analysed by Massively Parallel Sequencing of Multiple Synchro-nous Biopsies.
Magnes, T; Wagner, S; Thorner, AR; Neureiter, D; Klieser, E; Rinnerthaler, G; Weiss, L; Huemer, F; Schlick, K; Zaborsky, N; Steiner, M; Greil, R; Egle, A; Melchardt, T.
Cancers (Basel). 2021 Feb 6;13(4):650. doi: 10.3390/cancers13040650.
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Clonal evolution in diffuse large B-cell lymphoma with central nervous system recurrence.
Magnes, T; Wagner, S; Thorner, AR; Neureiter, D; Klieser, E; Rinnerthaler, G; Weiss, L; Huemer, F; Zaborsky, N; Steiner, M; Weis, S; Greil, R; Egle, A; Melchardt, T.
ESMO Open. 2021 Feb;6(1):100012. doi: 10.1016/j.esmoop.2020.100012. Epub 2021 Jan 4.
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Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study.
Pleyer, L; Leisch, M; Kourakli, A; Padron, E; Maciejewski, JP; Xicoy Cirici, B; Kaivers, J; Ungerstedt, J; Heibl, S; Patiou, P; Hunter, AM; Mora, E; Geissler, K; Dimou, M; Jimenez Lorenzo, MJ; Melchardt, T; Egle, A; Viniou, AN; Patel, BJ; Arnan, M; Valent, P; Roubakis, C; Bernal Del Castillo, T; Galanopoulos, A; Calabuig Muñoz, M; Bonadies, N; Medina de Almeida, A; Cermak, J; Jerez, A; Montoro, MJ; Cortés, A; Avendaño Pita, A; Lopez Andrade, B; Hellstroem-Lindberg, E; Germing, U; Sekeres, MA; List, AF; Symeonidis, A; Sanz, GF; Larcher-Senn, J; Greil, R.
Lancet Haematol. 2021 Feb;8(2):e135-e148. doi: 10.1016/S2352-3026(20)30374-4.
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Overcoming negative predictions of microRNA expressions to gemcita-bine response with FOLFIRINOX in advanced pancreatic cancer patients.
Schlick, K; Hohla, F; Hamacher, F; Hackl, H; Hufnagl, C; Markus, S; Magnes, T; Gampenrieder, SP; Melchardt, T; Stattner, S; Hauser-Kronberger, C; Greil, R; Rinnerthaler, G.
Future Sci OA. 2020 Nov 30;7(2):FSO644. doi: 10.2144/fsoa-2020-0128.
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Ramucirumab plus FOLFIRI or irinotecan as second-line therapy in ad-vanced or metastatic gastric or gastroesophageal junction adenocarci-noma.
Schlintl, V; Huemer, F; Greil, R; Weiss, L.
J Gastrointest Oncol. 2021 Apr;12(2):906-909. doi: 10.21037/jgo-20-230.
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Protein kinase C-β-dependent changes in the glucose metabolism of bo-ne marrow stromal cells of chronic lymphocytic leukemia.
von Heydebrand, F; Fuchs, M; Kunz, M; Voelkl, S; Kremer, AN; Oostendorp, RAJ; Wilke, J; Leitges, M; Egle, A; Mackensen, A; Lutzny-Geier, G.
Stem Cells. 2021 Jun;39(6):819-830. doi: 10.1002/stem.3352. Epub 2021 Feb 17.
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Transferring MINDACT to Daily Routine: Implementation of the 70-Gene Signature in Luminal Early Breast Cancer - Results from a Prospective Registry of the Austrian Group Medical Tumor Therapy (AGMT)
Westphal, T; Gampenrieder, SP; Rinnerthaler, G; Balic, M; Posch, F; Dan-dachi, N; Hauser-Kronberger, C; Reitsamer, R; Sotlar, K; Radl, B; Suppan, C; Stoger, H; Greil, R.
BREAST CARE. 2021; DOI: 10.1159/000512467.
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Alemtuzumab plus CHOP versus CHOP in elderly patients with peripheral T-cell lymphoma: the DSHNHL2006-1B/ACT-2 trial.
Wulf, GG; Altmann, B; Ziepert, M; DxxxAmore, F; Held, G; Greil, R; Tournilhac, O; Relander, T; Viardot, A; Wilhelm, M; Wilhelm, C; Pezzutto, A; Zijlstra, JM; Van Den Neste, E; Lugtenburg, PJ; Doorduijn, JK; van Gelder, M; van Imhoff, GW; Zettl, F; Braulke, F; Nickelsen, M; Glass, B; Rosenwald, A; Gaulard, P; Loeffler, M; Pfreundschuh, M; Schmitz, N; Trumper, L.
Leukemia. 2021 Jan;35(1):143-155. doi: 10.1038/s41375-020-0838-5. Epub 2020 May 7.
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2020
Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor-positive Early Breast Cancer: Results from the ABCSG Trial 5.
Bago-Horvath, Z; Rudas, M; Singer, CF; Greil, R; Balic, M; Lax, SF; Kwasny, W; Hulla, W; Gnant, M; Filipits, M.
Clin Cancer Res. 2020 Nov 1;26(21):5682-5688. doi: 10.1158/1078-0432.CCR-20-0673. Epub 2020 Jun 16.
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Real-world non-interventional long-term post-authorisation safety study of ruxolitinib in myelofibrosis.
Barraco, F; Greil, R; Herbrecht, R; Schmidt, B; Reiter, A; Willenbacher, W; Rayma-kers, R; Liersch, R; Wroclawska, M; Pack, R; Burock, K; Karumanchi, D; Gisslinger, H.
Br J Haematol. 2020 Jun 24. doi: 10.1111/bjh.16729. Online ahead of print.
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External validation of the prognostic relevance of the advanced lung cancer in-flammation index (ALI) in pancreatic cancer patients.
Barth, DA; Brenner, C; Riedl, JM; Prinz, F; Klocker, EV; Schlick, K; Kornprat, P; Lackner, K; St?ger, H; Stotz, M; Gerger, A; Pichler, M.
Cancer Med. 2020 Aug;9(15):5473-5479. doi: 10.1002/cam4.3233. Epub 2020 Jun 14.
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The EndoPredict score predicts response to neoadjuvant chemotherapy and neoendocrine therapy in hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer patients from the ABCSG-34 trial.
Dubsky, PC; Singer, CF; Egle, D; Wette, V; Petru, E; Balic, M; Pichler, A; Greil, R; Petzer, AL; Bago-Horvath, Z; Fesl, C; Meek, SM; Kronenwett, R; Rudas, M; Gnant, M; Filipits, M.
Eur J Cancer . 2020 Jul;134:99-106. doi: 10.1016/j.ejca.2020.04.020. Epub 2020 Jun 2.
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Endocrine therapy with or without whole breast irradiation in low-risk breast cancer patients after breast-conserving surgery: 10-year results of the Austrian Breast and Colorectal Cancer Study Group 8A trial.
Fastner, G; Sedlmayer, F; Widder, J; Metz, M; Geinitz, H; Kapp, K; Fesl, C; Sölkner, L; Greil, R; Jakesz, R; Kwasny, W; Heck, D; Bjelic-Radisic, V; Balic, M; Stöger, H; Wieder, U; Zwrtek, R; Semmler, D; Horvath, W; Melbinger-Zeinitzer, E; Wiesholzer, M; Wette, V; Gnant, M.
Eur J Cancer. 2020 Mar;127:12-20. doi: 10.1016/j.ejca.2019.11.024. Epub 2020 Jan 18.
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Dysphagia in the Context of a Serious Systemic Disease.
Ferstl, FS; Gampenrieder, SP; Renneberg, F; Roesch, S.
Dysphagia. 2020 Jul 22. doi: 10.1007/s00455-020-10155-6. Online ahead of print.
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RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia.
Gassner, FJ; Zaborsky, N; Buchumenski, I; Levanon, EY; Gatterbauer, M; Schubert, M; Rauscher, S; Hebenstreit, D; Nadeu, F; Campo, E; Egle, A; Greil, R; Geisberger, R.
Leukemia. 2020 Jul 30. doi: 10.1038/s41375-020-0995-6. Online ahead of print.
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RNA Editing Alters miRNA Function in Chronic Lymphocytic Leukemia.
Gassner, FJ; Zaborsky, N; Feldbacher, D; Greil, R; Geisberger, R.
Cancers (Basel). 2020 May 5;12(5):1159. doi: 10.3390/cancers12051159.
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Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity.
Grund-Gröschke, S; Ortner, D; Szenes-Nagy, AB; Zaborsky, N; Weiss, R; Neureiter, D; Wipplinger, M; Risch, A; Hammerl, P; Greil, R; Sibilia, M; Gratz, IK; Stoitzner, P; Aberger, F.
Mol Oncol. 2020 Sep;14(9):1930-1946. doi: 10.1002/1878-0261.12758. Epub 2020 Jul 21.
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CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.
Gutjahr, JC; Bayer, E; Yu, X; Laufer, JM; Höpner, JP; Tesanovic, S; Härzschel, A; Auer, G; Rieß, T; Salmhofer, A; Szenes, E; Haslauer, T; Durand-Onayli, V; Ramspa-cher, A; Pennisi, SP; Artinger, M; Zaborsky, N; Chigaev, A; Aberger, F; Neureiter, D; Pleyer, L; Legler, DF; Orian-Rousseau, V; Greil, R; Hartmann, TN.
Haematologica. 2020 Jul 2;haematol.2019.231944. doi: 10.3324/haematol.2019.231944. Online ahead of print.
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"I was seen by a radiologist, but unfortunately I can't remember the name and I still have questions. What should I do?" Radiologists should give thoughts to improve service professionalism and patient esteem.
Gutzeit, A; Fischmann, A; Forstner, R; Goette, R; Herzog, B; Kurtz, C; Hebler, C; La-dinger, A; Froehlich, JM; Blautzik, J; Kolokythas, O; Matoori, S; Kos, S; Reischauer, C; Schefer, H; Dubsky, P; Gampenrieder, SP; Hergan, K; Gaissmaier, W; Koh, DM; Meissnitzer, M.
Cancer Imaging. 2020 Feb 13;20(1):18. doi: 10.1186/s40644-020-0292-7.
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Impact of PD-L1 Scores and Changes on Clinical Outcome in Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiotherapy.
Huemer, F; Klieser, E; Neureiter, D; Schlintl, V; Rinnerthaler, G; Pagès, F; Kirilovsky, A; El Sissy, C; Iglseder, W; Singhartinger, F; Jäger, T; Dinnewitzer, A; Zaborsky, N; Steiner, M; Greil, R; Weiss, L.
J Clin Med. 2020 Aug 27;9(9):2775. doi: 10.3390/jcm9092775.
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Combination Strategies for Immune-Checkpoint Blockade and Response Prediction by Artificial Intelligence.
Huemer, F; Leisch, M; Geisberger, R; Melchardt, T; Rinnerthaler, G; Zaborsky, N; Greil, R.
Int J Mol Sci. 2020 Apr 19;21(8):2856. doi: 10.3390/ijms21082856.
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Hospitalizations and Clinical Outcome in Metastatic Colorectal Cancer During Regorafenib or TAS-102 Therapy.
Huemer, F; Piringer, G; Schlintl, V; Hackl, H; Rinnerthaler, G; Thaler, J; Greil, R; Weiss, L.
Cancers (Basel). 2020 Sep 30;12(10):E2812. doi: 10.3390/cancers12102812.
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Evaluation of circulating cell-free DNA as a molecular monitoring tool in patients with metastatic cancer.
Hufnagl, C; Leisch, M; Weiss, L; Melchardt, T; Moik, M; Asslaber, D; Roland, G; Steininger, P; Meissnitzer, T; Neureiter, D; Greil, R; Egle, A.
Oncol Lett. 2020 Feb;19(2):1551-1558. doi: 10.3892/ol.2019.11192. Epub 2019 Dec 9.
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Structure-Guided Identification of Black Cohosh (Actaea racemosa) Triterpenoids with In Vitro Activity against Multiple Myeloma.
Johrer, K; Stuppner, H; Greil, R; Cicek, SS.
Molecules. 2020 Feb 11;25(4):766. doi: 10.3390/molecules25040766.
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Decreased Activity of Circulating Butyrylcholinesterase in Blood Is an Independent Prognostic Marker in Pancreatic Cancer Patients.
Klocker, EV; Barth, DA; Riedl, JM; Prinz, F; Szkandera, J; Schlick, K; Kornprat, P; Lackner, K; Lindenmann, J; Stoger, H; Stotz, M; Gerger, A; Pichler, M.
Cancers (Basel). 2020 May 4;12(5):1154. doi: 10.3390/cancers12051154.
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IDO in MDS/AML disease progression and its role in resistance to azaci-tidine: a potential new drug target?
Leisch, M; Greil, R; Pleyer, L.
Br J Haematol. 2020 Aug;190(3):314-317. doi: 10.1111/bjh.16710. E-pub 2020 May 17.
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Quality of life in patients with relapsed/refractory multiple myeloma during ixazomib-thalidomide-dexamethasone induction and ixazomib mainte-nance therapy and comparison to the general population.
Ludwig, H; Ponisch, W; Knop, S; Egle, A; Hinke, A; Schreder, M; Lechner, D; Hajek, R; Gunsilius, E; Petzer, A; Weisel, K; Niederwieser, D; Einsele, H; Willenbacher, W; Rum-pold, H; Pour, L; Jelinek, T; Krenosz, KJ; Meckl, A; Nolte, S; Melchardt, T; Greil, R; Zojer, N.
Leuk Lymphoma. 2020 Feb;61(2):377-386. doi: 10.1080/10428194.2019.1666381. E-pub 2019 Sep 26.
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Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer.
Murthy, RK; Loi, S; Okines, A; Paplomata, E; Hamilton, E; Hurvitz, SA; Lin, NU; Bor-ges, V; Abramson, V; Anders, C; Bedard, PL; Oliveira, M; Jakobsen, E; Bachelot, T; Shachar, SS; Müller, V; Braga, S; Duhoux, FP; Greil, R; Cameron, D; Carey, LA; Curigliano, G; Gelmon, K; Hortobagyi, G; Krop, I; Loibl, S; Pegram, M; Slamon, D; Pa-lanca-Wessels, MC; Walker, L; Feng, W; Winer, EP.
N Engl J Med. 2020 Feb 13;382(7):597-609. doi: 10.1056/NEJMoa1914609. Epub 2019 Dec 11.
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Neutropenic complications in the PANTHER phase III study of adjuvant tailored dose-dense chemotherapy in early breast cancer.
Papakonstantinou, A; Hedayati, E; Hellstrom, M; Johansson, H; Gnant, M; Steger, G; Greil, R; Untch, M; Moebus, V; Loibl, S; Foukakis, T; Bergh, J; Matikas, A.
Acta Oncol. 2020 Jan;59(1):75-81. doi: 10.1080/0284186X.2019.1670353. Epub 2019 Oct 4.
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Efficacy and Safety of Tailored and Dose-Dense Adjuvant Chemotherapy and Trastuzumab for Resected HER2-Positive Breast Cancer: Results From the Phase 3 PANTHER Trial.
Papakonstantinou, A; Matikas, A; Bengtsson, NO; Malmstrom, P; Hedayati, E; Steger, G; Untch, M; Hubbert, L; Johansson, H; Hellstrom, M; Gnant, M; Loibl, S; Greil, R; Moebus, V; Foukakis, T; Bergh, J.
Cancer. 2020 Mar 15;126(6):1175-1182. doi: 10.1002/cncr.32653. E-pub 2019 Dec 18.
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Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance.
Park, E; Chen, J; Moore, A; Mangolini, M; Santoro, A; Boyd, JR; Schjerven, H; Ecker, V; Buchner, M; Williamson, JC; Lehner, PJ; Gasparoli, L; Williams, O; Bloehdorn, J; Stilgenbauer, S; Leitges, M; Egle, A; Schmidt-Supprian, M; Frietze, S; Ringshausen, I.
Sci Transl Med. 2020 Jan 15;12(526):eaax9340. doi: 10.1126/scitranslmed.aax9340.
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The AST/ALT (De Ritis) ratio predicts clinical outcome in patients with pancreatic cancer treated with first-line nab-paclitaxel and gemcitabine: post hoc analysis of an Austrian multicenter, noninterventional study.
Riedl, JM; Posch, F; Prager, G; Eisterer, W; Oehler, L; Sliwa, T; Wilthoner, K; Petzer, A; Pichler, P; Hubmann, E; Winder, T; Burgstaller, S; Korger, M; Andel, J; Greil, R; Neumann, HJ; Pecherstorfer, M; Philipp-Abbrederis, K; Djanani, A; Gruenberger, B; Laengle, F; Woll, E; Gerger, A.
Ther Adv Med Oncol. 2020 Apr 10;12:1758835919900872. doi: 10.1177/1758835919900872. eCollection 2020.
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Low Expression of miR-20a-5p Predicts Benefit to Bevacizumab in Meta-static Breast Cancer Patients Treated within the TANIA Phase III Trial.
Rinnerthaler, G; Gampenrieder, SP; Hackl, H; Steiner, M; Monzo-Fuentes, C; Melchardt, T; Magnes, T; Huemer, F; Westphal, T; Hufnagl, C; Hauser-Kronberger, C; Egle, A; Greil, R.
J Clin Med. 2020 Jun 1;9(6):1663. doi: 10.3390/jcm9061663.
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Comparison of high tone therapy and transcutaneous electrical nerve stimulation therapy in chemotherapy-induced polyneuropathy.
Schaffler-Schaden, D; Sassmann, R; Johansson, T; Gampenrieder, SP; Rinnerthaler, G; Lampl, K; Herfert, J; Lenzhofer, C; Landkammer, YT; Rieder, F; Greil, R; Flamm, M; Niebauer, J.
Medicine (Baltimore). 2020; 99(19): e20149.
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Gemtuzumab Ozogamicin in NPM1-Mutated Acute Myeloid Leukemia: Early Results From the Prospective Randomized AMLSG 09-09 Phase III Study.
Schlenk, RF; Paschka, P; Krzykalla, J; Weber, D; Kapp-Schwoerer, S; Gaidzik, VI; Leis, C; Fiedler, W; Kindler, T; Schroeder, T; Mayer, K; Lübbert, M; Wattad, M; Götze, K; Horst, HA; Koller, E; Wulf, G; Schleicher, J; Bentz, M; Greil, R; Hertenstein, B; Krauter, J; Martens, U; Nachbaur, D; Abu Samra, M; Girschikofsky, M; Basara, N; Benner, A; Thol, F; Heuser, M; Ganser, A; Döhner, K; Döhner, H.
J Clin Oncol. 2020; 38(6):623-632.
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Efficacy and safety of the therapeutic cancer vaccine tecemotide (L-BLP25) in early breast cancer: Results from a prospective, randomised, neoad-juvant phase II study (ABCSG 34).
Singer, CF; Pfeiler, G; Hubalek, M; Bartsch, R; Stoger, H; Pichler, A; Petru, E; Bjelic-Radisic, V; Greil, R; Rudas, M; Tea, MKM; Wette, V; Petzer, AL; Sevelda, P; Egle, D; Dubsky, PC; Filipits, M; Fitzal, F; Exner, R; Jakesz, R; Balic, M; Tinchon, C; Bago-Horvath, Z; Frantal, S; Gnant, M.
EUR J CANCER. 2020; 132: 43-52.
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Dabrafenib plus trametinib in patients with BRAF.
Subbiah, V; Lassen, U; EElez, E; Italiano, A; Curigliano, G; Javle, M; de Braud, F; Pra-ger, GW; Greil, R; Stein, A; Fasolo, A; Schellens, JHM; Wen, PY; Viele, K; Boran, AD; Gasal, E; Burgess, P; Ilankumaran, P; Wainberg, ZA.
Lancet Oncol. 2020; 21(9):1234-1243.
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TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia.
Szenes, E; Harzschel, A; Decker, S; Tissino, E; Pischeli, J; Gutjahr, JC; Kissel, S; Pen-nisi, S; Hopner, JP; Egle, A; Zaborsky, N; Dierks, C; Follo, M; Chigaev, A; Zucchetto, A; Greil, R; Gattei, V; Hartmann, TN.
LEUKEMIA. 2020; 34(9): 2498-2502.
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Treatment with brentuximab vedotin plus bendamustine in unselected patients with CD30-positive aggressive lymphomas.
Wagner, SM; Melchardt, T; Egle, A; Magnes, T; Skrabs, C; Staber, P; Simonitsch-Klupp, I; Panny, M; Lehner, B; Greil, R; Keil, F; Jäger, U; Sillaber, C.
Eur J Haematol. 2020; 104(3):251-258.
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Ropeginterferon alfa-2b for the treatment of patients with polycythemia vera.
Wagner, SM; Melchardt, T; Greil, R.
DRUG TODAY. 2020; 56(3): 195-202.
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Alemtuzumab plus CHOP versus CHOP in elderly patients with peri-pheral T-cell lymphoma: the DSHNHL2006-1B/ACT-2 trial.
Wulf, GG; Altmann, B; Ziepert, M; DxxxAmore, F; Held, G; Greil, R; Tournilhac, O; Relander, T; Viardot, A; Wilhelm, M; Wilhelm, C; Pezzutto, A; Zijlstra, JM; Van Den Neste, E; Lugtenburg, PJ; Doorduijn, JK; van Gelder, M; van Imhoff, GW; Zettl, F; Braulke, F; Nickelsen, M; Glass, B; Rosenwald, A; Gaulard, P; Loeffler, M; Pfreund-schuh, M; Schmitz, N; Trumper, L.
Leukemia . 2020 May 7. doi: 10.1038/s41375-020-0838-5. Online ahead of print.
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2019
B-cell-specific IRF4 deletion accelerates chronic lymphocytic leukemia development by enhanced tumor immune evasion.
Asslaber, D; Qi, Y; Maeding, N; Steiner, M; Denk, U; Hopner, JP; Hartmann, TN; Zaborsky, N; Greil, R; Egle, A.
Blood. 2019 Nov 14;134(20):1717-1729. doi: 10.1182/blood.2019000973.
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BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation.
Asslaber, D; Wacht, N; Leisch, M; Qi, Y; Maeding, N; Hufnagl, C; Jansko, B; Zaborsky, N; Villunger, A; Hartmann, TN; Greil, R; Egle, A.
Clin Cancer Res. 2019 Mar 15;25(6):1901-1912. doi: 10.1158/1078-0432.CCR-18-1548. Epub 2018 Nov 28.
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Prevalence of comorbidity in cancer patients scheduled for systemic anticancer treatment in Austria. A cross-sectional multicentre observational study.
Balic, M; Hilbe, W; Gusel, S; Fiegl, M; Ludwig, H; Mayrbaurl, B; Thaler, J; Samonigg, H; Hegenbarth, K; Eisner, F; Mlineritsch, B; Greil, R; Schandl, MJ; Weltermann, A; Petzer, A; Fuchs, D; Stangl, W; Krippl, P; Stauder, R; Stoger, H.
memo - Magazine of European Medical Oncology volume 12, pages290–296(2019).
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Intense Uptake of Liposomal Curcumin by Multiple Myeloma Cell Lines: Comparison to Normal Lymphocytes, Red Blood Cells and Chronic Lymphocytic Leukemia Cells.
Bolger, GT; Licollari, A; Bagshaw, R; Tan, AM; Greil, R; Vcelar, B; Majeed, M; Sordillo, P.
Anticancer Res. 2019 Mar;39(3):1161-1168. doi: 10.21873/anticanres.13225.
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Pharmacokinetics of liposomal curcumin (Lipocurc™) infusion: effect of co-medication in cancer patients and comparison with healthy individuals.
Bolger, GT; Licollari, A; Tan, A; Greil, R; Vcelar, B; Greil-Ressler, S; Weiss, L; Schön-lieb, C; Magnes, T; Radl, B; Majeed, M; Sordillo, PP.
Cancer Chemother Pharmacol. 2019 Feb;83(2):265-275. doi: 10.1007/s00280-018-3730-5. Epub 2018 Nov 14.
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Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study.
Burtness, B; Harrington, KJ; Greil, R; Soulieres, D; Tahara, M; de Castro, G; Psyrri, A; Baste, N; Neupane, P; Bratland, A; Fuereder, T; Hughes, BGM; Mesia, R; Ngam-phaiboon, N; Rordorf, T; Ishak, WZW; Hong, RL; Mendoza, RG; Roy, A; Zhang, YY; Gumuscu, B; Cheng, JD; Jin, F; Rischin, D.
Lancet. 2019 Nov 23;394(10212):1915-1928. doi: 10.1016/S0140-6736(19)32591-7. Epub 2019 Nov 1.
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Rituximab maintenance overcomes the negative prognostic factor of obesity in CLL: Subgroup analysis of the international randomized AGMT CLL-8a mabtenance trial.
Egle, A; Melchardt, T; Obrtlíková, P; Smolej, L; Kozák, T; Steurer, M; Andel, J; Burgs-taller, S; Mikušková, E; Gercheva, L; Nösslinger, T; Papajík, T; Ladická, M; Girschiko-fsky, M; Hrubiško, M; Jäger, U; Voskova, D; Pecherstorfer, M; Králiková, E; Bur-coveanu, C; Spasov, E; Petzer, A; Mihaylov, G; Raynov, J; Oexle, H; Zabernigg, A; Flochová, E; Palášthy, S; Stehlíková, O; Doubek, M; Altenhofer, P; Weiss, L; Mag-nes, T; Pleyer, L; Klingler, A; Mayer, J; Greil, R.
Cancer Med. 2019 Apr;8(4):1401-1405. doi: 10.1002/cam4.1980. Epub 2019 Mar 19.
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Prediction of Distant Recurrence Using EndoPredict Among Women with ER +, HER2 - Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only.
Filipits, M; Dubsky, P; Rudas, M; Greil, R; Balic, M; Bago-Horvath, Z; Singer, CF; Hlauschek, D; Brown, K; Bernhisel, R; Kronenwett, R; Lancaster, JM; Fitzal, F; Gnant, M.
Clin Cancer Res. 2019 Jul 1;25(13):3865-3872. doi: 10.1158/1078-0432.CCR-19-0376. Epub 2019 May 7.
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Radiologic complete response (rCR) in contrast-enhanced magnetic resonance imaging (CE-MRI) after neoadjuvant chemotherapy for early breast cancer predicts recurrence-free survival but not pathologic complete response (pCR).
Gampenrieder, SP; Peer, A; Weismann, C; Meissnitzer, M; Rinnerthaler, G; Webhof-er, J; Westphal, T; Riedmann, M; Meissnitzer, T; Egger, H; Klaassen Federspiel, F; Reitsamer, R; Hauser-Kronberger, C; Stering, K; Hergan, K; Mlineritsch, B; Greil, R.
Breast Cancer Res. 2019 Jan 31;21(1):19. doi: 10.1186/s13058-018-1091-y.
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Adjuvant denosumab in postmenopausal patients with hormone receptor-positive breast cancer (ABCSG-18): disease-free survival results from a rando-mised, double-blind, placebo-controlled, phase 3 trial.
Gnant, M; Pfeiler, G; Steger, GG; Egle, D; Greil, R; Fitzal, F; Wette, V; Balic, M; Hasl-bauer, F; Melbinger-Zeinitzer, E; Bjelic-Radisic, V; Jakesz, R; Marth, C; Sevelda, P; Mlineritsch, B; Exner, R; Fesl, C; Frantal, S; Singer, CF.
Lancet Oncol. 2019 Mar;20(3):339-351. doi: 10.1016/S1470-2045(18)30862-3. Epub 2019 Feb 19.
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Baseline Absolute Lymphocyte Count and ECOG Performance Score Are Associated with Survival in Advanced Non-Small Cell Lung Cancer Undergoing PD-1/PD-L1 Blockade.
Huemer, F; Lang, D; Westphal, T; Gampenrieder, SP; Hutarew, G; Weiss, L; Hackl, H; Lamprecht, B; Rinnerthaler, G; Greil, R.
J Clin Med. 2019 Jul 10;8(7):1014. doi: 10.3390/jcm8071014.
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Durable remissions with venetoclax monotherapy in secondary AML refractory to hypomethylating agents and high expression of BCL-2 and/or BIM.
Huemer, F; Melchardt, T; Jansko, B; Wahida, A; Jilg, S; Jost, PJ; Klieser, E; Katja, S; Magnes, T; Pleyer, L; Greil-Ressler, S; Rass, C; Greil, R; Egle, A.
Eur J Haematol. 2019 May;102(5):437-441. doi: 10.1111/ejh.13218. Epub 2019 Feb 28.
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Association between antibiotics use and outcome in patients with NSCLC trea-ted with immunotherapeutics.
Huemer, F; Rinnerthaler, G; Lang, D; Hackl, H; Lamprecht, B; Greil, R.
Ann Oncol. 2019 Apr 1;30(4):652-653. doi: 10.1093/annonc/mdz021.
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Regorafenib Is Associated With Increased Skeletal Muscle Loss Compared to TAS-102 in Metastatic Colorectal Cancer.
Huemer, F; Schlintl, V; Hecht, S; Hackl, H; Melchardt, T; Rinnerthaler, G; Greil, R; Weiss, L.
Clin Colorectal Cancer. 2019 Jun;18(2):159-166.e3. doi: 10.1016/j.clcc.2019.04.003. Epub 2019 Apr 11.
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Therapy Line and Associated Predictors of Response to PD-1/PD-L1-Inhibitor Monotherapy in Advanced Non-small-Cell Lung Cancer: A Retrospective Bi-centric Cohort Study.
Lang, D; Huemer, F; Rinnerthaler, G; Horner, A; Wass, R; Brehm, E; Akbari, K; Gra-nitz, M; Hutarew, G; Kaiser, B; Greil, R; Lamprecht, B.
Target Oncol. 2019 Dec;14(6):707-717. doi: 10.1007/s11523-019-00679-9.
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Plitidepsin: a potential new treatment for relapsed/refractory multiple myeloma.
Leisch, M; Egle, A; Greil, R.
Future Oncol. 2019 Jan;15(2):109-120. doi: 10.2217/fon-2018-0492. Epub 2018 Aug 16.
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Next Generation Sequencing in AML-On the Way to Becoming a New Standard for Treatment Initiation and/or Modulation?
Leisch, M; Jansko, B; Zaborsky, N; Greil, R; Pleyer, L.
Cancers (Basel). 2019 Feb 21;11(2):252. doi: 10.3390/cancers11020252.
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Large platelet size is associated with poor outcome in patients with metastatic pancreatic cancer.
Lembeck, AL; Posch, F; Klocker, EV; Szkandera, J; Schlick, K; Stojakovic, T; Korn-prat, P; Lackner, C; Gerger, A; Stoeger, H; Stotz, M; Pichler, M.
Clin Chem Lab Med. 2019 Apr 24;57(5):740-744. doi: 10.1515/cclm-2018-0016.
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Ixazomib-Thalidomide-Dexamethasone for induction therapy followed by I-xazomib maintenance treatment in patients with relapsed/refractory multiple myeloma
Ludwig, H; Poenisch, W; Knop, S; Egle, A; Schreder, M; Lechner, D; Hajek, R; Gun-silius, E; Krenosz, KJ; Petzer, A; Weisel, K; Niederwieser, D; Einsele, H; Willenba-cher, W; Melchardt, T; Greil, R; Zojer, N.
Br J Cancer. 2019 Oct;121(9):751-757. doi: 10.1038/s41416-019-0581-8. Epub 2019 Sep 27.
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Dose tailoring of adjuvant chemotherapy for breast cancer based on hematolo-gic toxicities: further results from the prospective PANTHER study with focus on obese patients.
Matikas, A; Foukakis, T; Moebus, V; Greil, R; Bengtsson, NO; Steger, GG; Untch, M; Johansson, H; Hellström, M; Malmström, P; Gnant, M; Loibl, S; Bergh, J.
Ann Oncol. 2019 Jan 1;30(1):109-114. doi: 10.1093/annonc/mdy475.
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Ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab in first-line treatment of chronic lymphocytic leukaemia (iLLUMINATE): a multicentre, randomised, open-label, phase 3 trial.
Moreno, C; Greil, R; Demirkan, F; Tedeschi, A; Anz, B; Larratt, L; Simkovic, M; Sa-moilova, O; Novak, J; Ben-Yehuda, D; Strugov, V; Gill, D; Gribben, JG; Hsu, E; Lih, CJ; Zhou, C; Clow, F; James, DF; Styles, L; Flinn, IW.
Lancet Oncol. 2019 Jan;20(1):43-56. doi: 10.1016/S1470-2045(18)30788-5. Epub 2018 Dec 3.
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Mouse models to decipher anti-tumor immunity.
Parigger, T; Greil, R; Zaborsky, N.
Oncotarget. 2019 Aug 20;10(49):5005-5006. doi: 10.18632/oncotarget.27111.
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Pancreatic cancer in young adults: changes, challenges, and solutions.
Primavesi, F; Stättner, S; Schlick, K; Kiesslich, T; Mayr, C; Klieser, E; Urbas, R; Neureiter, D.
Onco Targets Ther. 2019 May 6;12:3387-3400. doi: 10.2147/OTT.S176700. eCollec-tion 2019.
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Good Response of Lupus Hepatitis to Mycophenolate Mofetil and Belimumab as of Lupus Exanthema to Rituximab: A Case Report.
Psenak, O; Studnicka-Benke, A; Haufe, H; Greil, R.
Rheumatology: Current Research. 2019; 9(1): 247-251.
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HER2 Directed Antibody-Drug-Conjugates beyond T-DM1 in Breast Cancer.
Rinnerthaler, G; Gampenrieder, SP; Greil, R.
Int J Mol Sci. 2019 Mar 5;20(5):1115. doi: 10.3390/ijms20051115.
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Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination.
Rivera, FJ; de la Fuente, AG; Zhao, C; Silva, ME; Gonzalez, GA; Wodnar, R; Feichtner, M; Lange, S; Errea, O; Priglinger, E; OSullivan, A; Romanelli, P; Jadasz, JJ; Brachtl, G; Greil, R; Tempfer, H; Traweger, A; Bátiz, LF; Küry, P; Couillard-Despres, S; Franklin, RJM; Aigner, L.
Glia. 2019 Aug;67(8):1510-1525. doi: 10.1002/glia.23624. Epub 2019 Apr 30.
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Patterns of care in metastatic pancreatic cancer: patient selection in clinical routine.
Scheithauer, W; Putora, PM; Grunberger, B; Eisterer, W; Woll, E; Prager, G; Scha-berl-Moser, R; Greil, R; Glatzer, M.
Therap Adv Gastroenterol. 2019 Sep 23;12:1756284819877635. doi: 10.1177/1756284819877635. eCollection 2019.
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Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD.
Schlenk, RF; Weber, D; Fiedler, W; Salih, HR; Wulf, G; Salwender, H; Schroeder, T; Kindler, T; Lübbert, M; Wolf, D; Westermann, J; Kraemer, D; Götze, KS; Horst, HA; Krauter, J; Girschikofsky, M; Ringhoffer, M; Südhoff, T; Held, G; Derigs, HG; Schro-ers, R; Greil, R; Grießhammer, M; Lange, E; Burchardt, A; Martens, U; Hertenstein, B; Marretta, L; Heuser, M; Thol, F; Gaidzik, VI; Herr, W; Krzykalla, J; Benner, A; Döhner, K; Ganser, A; Paschka, P; Döhner, H.
Blood. 2019 Feb 21;133(8):840-851. doi: 10.1182/blood-2018-08-869453. Epub 2018 Dec 18.
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C-Reactive Protein and Neutrophil/Lymphocytes Ratio: Prognostic Indicator for Doubling overall survival Prediction in Pancreatic Cancer Patients.
Schlick, K; Magnes, T; Huemer, F; Ratzinger, L; Weiss, L; Pichler, M; Melchardt, T; Greil, R; Egle, A.
J Clin Med. 2019 Oct 25;8(11):1791. doi: 10.3390/jcm8111791.
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Lignans and sesquiterpene lactones from Hypochaeris radicata subsp. neapoli-tana (Asteraceae, Cichorieae).
Shulha, O; Cicek, SS; Wangensteen, H; Kroes, J; Mader, M; Girreser, U; Sendker, J; Johrer, K; Greil, R; Schuhly, W; Mangoni, A; Grauso, L; van Thriel, C; Zidorn, C.
Phytochemistry. 2019 Sep;165:112047. doi: 10.1016/j.phytochem.2019.05.020. Epub 2019 Jun 13.
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Randomized phase III study (ADMYRE) of plitidepsin in combination with dexa-methasone vs. dexamethasone alone in patients with relapsed/refractory mul-tiple myeloma.
Spicka, I; Ocio, EM; Oakervee, HE; Greil, R; Banh, RH; Huang, SY; DxxxRozario, JM; Dimopoulos, MA; Martinez, S; Extremera, S; Kahatt, C; Alfaro, V; Carella, AM; Meuleman, N; Hajek, R; Symeonidis, A; Min, CK; Cannell, P; Ludwig, H; Sonneveld, P; Mateos, MV.
Ann Hematol. 2019 Sep;98(9):2139-2150. doi: 10.1007/s00277-019-03739-2. Epub 2019 Jun 25.
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Systemic treatment of metastatic breast cancer: SABCS 2018.
Westphal, T; Gampenrieder, SP; Greil, R.
MEMO-MAG EUR MED ONC. 2019; 12(3): 253-256.
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Pixantrone demonstrates significant in vitro activity against multiple myeloma and plasma cell leukemia.
Willenbacher, E; Johrer, K; Willenbacher, W; Flogel, B; Greil, R; Kircher, B.
Ann Hematol. 2019 Nov;98(11):2569-2578. doi: 10.1007/s00277-019-03797-6. Epub 2019 Oct 18.
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Cytotoxic Properties of Damiana ( Turnera diffusa) Extracts and Constituents and A Validated Quantitative UHPLC-DAD Assay.
Willer, J; Johrer, K; Greil, R; Zidorn, C; Cicek, SS.
Molecules. 2019 Feb 28;24(5):855. doi: 10.3390/molecules24050855.
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Exome sequencing of the TCL1 mouse model for CLL reveals genetic hetero-geneity and dynamics during disease development.
Zaborsky, N; Gassner, FJ; Höpner, JP; Schubert, M; Hebenstreit, D; Stark, R; Assla-ber, D; Steiner, M; Geisberger, R; Greil, R; Egle, A.
Leukemia. 2019 Apr;33(4):957-968. doi: 10.1038/s41375-018-0260-4. Epub 2018 Sep 27.
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2018
Distribution of Curcumin and THC in Peripheral Blood Mononuclear Cells Isolated from Healthy Individuals and Patients with Chronic Lymphocytic Leukemia.
Bolger, GT, Licollari, A, Tan, A, Greil, R, Pleyer, L, Vcelar, B, Majeed, M, Sordillo, P.
Anticancer Res. 2018, 38(1): 12-130.
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Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia.
Tissino, E, Benedetti, D, Herman, SEM, Ten Hacken, E, Ahn, IE, Chaffee, KG, Rossi, FM, Dal Bo, M, Bulian, P, Bomben, R, Bayer, E, Härzschel, A, Gutjahr, JC, Postorino, M, Santinelli, E, Ayed, A, Zaja, F, Chiarenza, A, Pozzato, G, Chigaev, A, Sklar, LA, Burger, JA, Ferrajoli, A, Shanafelt, TD, Wiestner, A, Del Poeta, G, Hartmann, TN, Gattei, V, Zucchetto, A.
J Exp Med. 2018.
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Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia.
Gutjahr, JC, Szenes, E, Tschech, L, Asslaber, D, Schlederer, M, Roos, S, Yu, X, Girbl, T, Sternberg, C, Egle, A, Aberger, F, Alon, R, Kenner, L, Greil, R, Orian-Rousseau, V, Hartmann, TN.
Blood. 2018.
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Sidedness and TP53 mutations impact OS in anti-EGFR but not anti-VEGF treated mCRC - an analysis of the KRAS registry of the AGMT (Arbeitsgemeinschaft Medikamentöse Tumortherapie).
Huemer, F, Thaler, J, Piringer, G, Hackl, H, Pleyer, L, Hufnagl, C, Weiss, L, Greil, R.
BMC Cancer. 2018, 18(1): 11.
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PET-guided treatment in patients with advanced-stage Hodgkins lymphoma (HD18): final results of an open-label, international, randomised phase 3 trial by the German Hodgkin Study Group.
Borchmann, P, Goergen, H, Kobe, C, Lohri, A, Greil, R, Eichenauer, DA, Zijlstra, JM, Markova, J, Meissner, J, Feuring-Buske, M, Hüttmann, A, Dierlamm, J, Soekler, M, Beck, HJ, Willenbacher, W, Ludwig, WD, Pabst, T, Topp, MS, Hitz, F, Bentz, M, Keller, UB, Kühnhardt, D, Ostermann, H, Schmitz, N, Hertenstein, B, Aulitzky, W, Maschmeyer, G, Vieler, T, Eich, H, Baues, C, Stein, H, Fuchs, M, Kuhnert, G, Diehl, V, Dietlein, M, Engert, A.
Lancet. 2018, 390(10114): 2790-2802.
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Establishment and validation of a novel risk model for estimating time to first treatment in 120 patients with chronic myelomonocytic leukaemia.
Huemer, F, Weiss, L, Faber, V, Neureiter, D, Egle, A, Geissler, K, Voskova, D, Zebisch, A, Burgstaller, S, Pichler, A, Stauder, R, Sperr, W, Lang, A, Pfeilstöcker, M, Machherndl-Spandl, S, Stampfl, M, Greil, R, Pleyer, L.
Wien Klin Wochenschr. 2018.
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Clonal evolution and heterogeneity in metastatic head and neck cancer-An analysis of the Austrian Study Group of Medical Tumour Therapy study group.
Melchardt, T, Magnes, T, Hufnagl, C, Thorner, AR, Ducar, M, Neureiter, D, Tränkenschuh, W, Klieser, E, Gaggl, A, Rösch, S, Rasp, G, Hartmann, TN, Pleyer, L, Rinnerthaler, G, Weiss, L, Greil, R, Egle, A.
Eur J Cancer. 2018, 93:69-78.
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Incidence and risk factors for relapses in HIV-associated non-Hodgkin-lymphoma as observed in the German HIV-related lymphoma cohort study.
Schommers, P, Gillor, D, Hentrich, M, Wyen, C, Wolf, T, Oette, M, Zoufaly, A, Wasmuth, JC, Bogner, JR, Müller, M, Esser, S, Schleicher, A, Jensen, B, Stoehr, A, Behrens, G, Schultze, A, Siehl, J, Thoden, J, Taylor, N, Hoffmann, C.
Haematologica. 2018.
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The multiple myeloma treatment landscape: international guideline recommendations and clinical practice in Europe.
Cavo, M, Terpos, E, Bargay, J, Einsele, H, Cavet, J, Greil, R, de Wit, E.
Expert Rev Hematol. 2018, 11(3):219-237.
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Real life experience with frontline azacitidine in a large series of older adults with acute myeloid leukemia stratified by MRC/LRF score: results from the expanded international E-ALMA series (E-ALMA+).
Falantes, J, Pleyer, L, Thépot, S, Almeida, AM, Maurillo, L, Martínez-Robles, V, Stauder, R, Itzykson, R, Pinto, R, Venditti, A, Bargay, J, Burgstaller, S, Martínez, MP, Seegers, V, Cortesão, E, Foncillas, MÁ, Gardin, C, Montesinos, P, Musto, P, Fenaux, P, Greil, R, Sanz, MA, Ramos, F,
Leuk Lymphoma. 2018, 59(5):1113-1120.
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A prospective, multicenter pilot study to investigate the feasibility and safety of a 1-year controlled exercise training after adjuvant chemotherapy in colorectal cancer patients.
Piringer, G, Fridrik, M, Fridrik, A, Leiherer, A, Zabernigg, A, Greil, R, Eisterer, W, Tschmelitsch, J, Lang, A, Frantal, S, Burgstaller, S, Gnant, M, Thaler, J.
Support Care Cancer. 2018, 26(4):1345-1352.
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A phase I study of lenalidomide in patients with chronic myelomonocytic leukemia (CMML) - AGMT_CMML-1.
Burgstaller, S, Stauder, R, Kuehr, T, Lang, A, Machherndl-Spandl, S, Mayrbaeurl, B, Noesslinger, T, Petzer, A, Valent, P, Greil, R, Thaler, J.
Leuk Lymphoma. 2018, 59(5):1121-1126.
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Imprecision and DNA Break Repair Biased towards Incompatible End Joining in Leukemia.
Gassner, FJ, Schubert, M, Rebhandl, S, Spandl, K, Zaborsky, N, Catakovic, K, Blaimer, S, Hebenstreit, D, Greil, R, Geisberger, R.
Mol Cancer Res. 2018, 16(3):428-438.
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Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes.
Domenyuk, V, Gatalica, Z, Santhanam, R, Wei, XX, Stark, A, Kennedy, P, Toussaint, B, Levenberg, S, Wang, J, Xiao, NQ, Greil, R, Rinnerthaler, G, Gampenrieder, SP, Heimberger, AB, Berry, DA, Barker, A, Quackenbush, J, Marshall, JL, Poste, G, Vacirca, JL, Vidal, GA, Schwartzberg, LS, Halbert, DD, Voss, A, Magee, D, Miglarese, MR, Famulok, M, Mayer, G, Spetzler, D.
Nat Commun. 2018, 9(1):1219.
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DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer.
Gampenrieder, SP, Rinnerthaler, G, Hackl, H, Pulverer, W, Weinhaeusel, A, Ilic, S, Hufnagl, C, Hauser-Kronberger, C, Egle, A, Risch, A, Greil, R.
THERANOSTICS. 2018, 8(8): 2278-2288.
Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity.
Wolf, M, Aglas, L, Twaroch, TE, Steiner, M, Huber, S, Hauser, M, Parigiani, MA, Hofer, H, Ebner, C, Bohle, B, Briza, P, Neubauer, A, Stolz, F, Wallner, M, Ferreira, F.
J Allergy Clin Immunol. 2018, 141(4):1488-1491.e5.
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Factor VII deficiency in major artery occlusion stroke.
Pikija, S, Gampenrieder, SP, Millesi, K, Pilz, G, Weis, S, Mutzenbach, JS.
Am J Hematol. 2018, 93(6):843-845.
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Nonmetastatic pancreatic cancer : Improved survival with chemoradiotherapy > 40 Gy after systemic treatment.
Bachmayer, S, Fastner, G, Vaszi, A, Iglseder, W, Kopp, P, Holzinger, J, Dinnewitzer, A, Rinnerthaler, G, Gampenrieder, SP, Emmanuel, K, Greil, R, Sedlmayer, F, Zehentmayr, F.
Strahlenther Onkol. 2018, 194(7):62-637.
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Fludarabine and rituximab with escalating doses of lenalidomide followed by lenalidomide/rituximab maintenance in previously untreated chronic lymphocytic leukaemia (CLL): the REVLIRIT CLL-5 AGMT phase I/II study.
Egle, A, Steurer, M, Melchardt, T, Weiss, L, Gassner, FJ, Zaborsky, N, Geisberger, R, Catakovic, K, Hartman, TN, Pleyer, L, Voskova, D, Thaler, J, Lang, A, Girschikofsky, M, Petzer, A, Greil, R.
Ann Hematol. 2018.
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Adding dasatinib to intensive treatment in core-binding factor acute myeloid leukemia-results of the AMLSG 11-08 trial.
Paschka, P, Schlenk, RF, Weber, D, Benner, A, Bullinger, L, Heuser, M, Gaidzik, VI, Thol, F, Agrawal, M, Teleanu, V, Lubbert, M, Fiedler, W, Radsak, M, Krauter, J, Horst, HA, Greil, R, Mayer, K, Kundgen, A, Martens, U, Heil, G, Salih, HR, Hertenstein, B, Schwanen, C, Wulf, G, Lange, E, Pfreundschuh, M, Ringhoffer, M, Girschikofsky, M, Heinicke, T, Kraemer, D, Gohring, G, Ganser, A, Dohner, K, Dohner, H.
LEUKEMIA. 2018, 32(7): 1621-1630.
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A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc™) in patients with locally advanced or metastatic cancer.
Greil, R, Greil-Ressler, S, Weiss, L, Schönlieb, C, Magnes, T, Radl, B, Bolger, GT, Vcelar, B, Sordillo, PP.
Cancer Chemother Pharmacol. 2018.
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Ruxolitinib therapy for myelofibrosis in Austria : Consensus on therapy management.
Krauth, MT, Burgstaller, S, Buxhofer-Ausch, V, Gastl, G, Geissler, K, Keil, F, Krippl, P, Melchardt, T, Petzer, A, Rumpold, H, Sliwa, T, Wöhrer, S, Wölfler, A, Gisslinger, H.
Wien Klin Wochenschr. 2018.
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Austrian recommendations for the management of polycythemia vera.
Burgstaller, S, Buxhofer-Ausch, V, Sliwa, T, Beham-Schmid, C, Gastl, G, Geissler, K, Melchardt, T, Krauth, M, Krippl, P, Petzer, A, Rumpold, H, Wölfler, A, Gisslinger, H.
Wien Klin Wochenschr. 2018.
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Outcome of Patients With Early-Stage Infradiaphragmatic Hodgkin Lymphoma: A Comprehensive Analysis From the German Hodgkin Study Group.
Sasse, S, Goergen, H, Plütschow, A, Böll, B, Eichenauer, DA, Fuchs, M, Behringer, K, Zijlstra, JM, Greil, R, Markova, J, Topp, MS, Meissner, J, Neubauer, A, Baues, C, Engert, A, Borchmann, P, von Tresckow, B.
J Clin Oncol. 2018, 36(25):2603-2611.
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Extensive leptomeningeal intracranial and spinal metastases in a patient with a supratentorial glioblastoma multiforme, IDH-wildtype: A case report.
Schwartz, C, Romagna, A, Machegger, L, Weiss, L, Huemer, F, Fastner, G, Kleindienst, W, Serge, W, Greil, R, Winkler, PA.
World Neurosurg. 2018.
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Remission maintenance treatment options in chronic lymphocytic leukemia.
Egle, A, Pleyer, L, Melchardt, T, Hartmann, TN, Greil, R.
Cancer Treat Rev. 2018, 70:5-66.
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News from ASCO 2018.
Balic, M, Dedic, N, De Mattos-Arruda, L, Gampenrieder, S.
BREAST CARE. 2018, 13(4): 298-302.
Impact of Breast Surgery in Primary Metastasized Breast Cancer: Outcomes of the Prospective Randomized Phase III ABCSG-28 POSYTIVE Trial.
Fitzal, F, Bjelic-Radisic, V, Knauer, M, Steger, G, Hubalek, M, Balic, M, Singer, C, Bartsch, R, Schrenk, P, Soelkner, L, Greil, R, Gnant, M.
Ann Surg. 2018.
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Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia.
Ball, B, Komrokji, RS, Ades, L, Sekeres, MA, DeZern, AE, Pleyer, L, Vey, N, Almeida, A, Germing, U, Cluzeau, T, Platzbecker, U, Gore, SD, Fenaux, P, Prebet, T.
BLOOD ADV. 2018, 2(16): 2063-2071.
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RNA Trans-Splicing Modulation via Antisense Molecule Interference.
Liemberger, B, Piñón Hofbauer, J, Wally, V, Arzt, C, Hainzl, S, Kocher, T, Murauer, EM, Bauer, JW, Reichelt, J, Koller, U.
Int J Mol Sci. 2018, 19(3).
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Ixazomib in combination with carboplatin in pretreated women with advanced triple-negative breast cancer, a phase I/II trial of the AGMT (AGMT MBC-10 trial).
Rinnerthaler, G, Gampenrieder, SP, Petzer, A, Burgstaller, S, Fuchs, D, Rossmann, D, Balic, M, Egle, D, Rumpold, H, Singer, CF, Bartsch, R, Petru, E, Melchardt, T, Ulmer, H, Mlineritsch, B, Greil, R.
BMC Cancer. 2018, 18(1): 1074.
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Elevated amylase in plasma represents an adverse prognostic marker in patients with metastatic pancreatic cancer : A retrospective analysis.
Asamer, E, Szkandera, J, Gibiser, P, Lembeck, AL, Stojakovic, T, Kornprat, P, Lackner, C, Winder, T, Schlick, K, Stoger, H, Gerger, A, Pichler, M, Stotz, M.
WIEN KLIN WOCHENSCHR. 2018, 130(19-20): 569-574.
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Supervised versus autonomous exercise training in breast cancer patients: A multicenter randomized clinical trial.
Westphal, T, Rinnerthaler, G, Gampenrieder, SP, Niebauer, J, Thaler, J, Pfob, M, Fuchs, D, Riedmann, M, Mayr, B, Reich, B, Melchardt, T, Mlineritsch, B, Pleyer, L, Greil, R.
Cancer Med. 2018.
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Does clinical outcome of birch pollen immunotherapy relate to induction of blocking antibodies preventing IgE from allergen binding? A pilot study monitoring responses during first year of AIT.
Huber, S, Lang, R, Steiner, M, Aglas, L, Ferreira, F, Wallner, M, Hawranek, T, Gadermaier, G.
Clin Transl Allergy. 2018, 8: 39.
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Novel models for prediction of benefit and toxicity with FOLFIRINOX treatment of pancreatic cancer using clinically available parameters.
Schlick, K, Magnes, T, Ratzinger, L, Jaud, B, Weiss, L, Melchardt, T, Greil, R, Egle, A.
PLoS One. 2018, 13(11): e0206688.
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Pharmacokinetics of liposomal curcumin (Lipocurc™) infusion: effect of co-medication in cancer patients and comparison with healthy individuals.
Bolger, GT, Licollari, A, Tan, A, Greil, R, Vcelar, B, Greil-Ressler, S, Weiss, L, Schönlieb, C, Magnes, T, Radl, B, Majeed, M, Sordillo, PP.
Cancer Chemother Pharmacol. 2018.
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ASCO 2018 highlights: metastatic breast cancer.
Rinnerthaler, G, Gampenrieder, SP, Greil, R.
MEMO-MAG EUR MED ONC. 2018, 11(4): 276-279.
A phase I study of lenalidomide in patients with chronic myelomonocytic leukemia (CMML) - AGMT_CMML-1.
Burgstaller, S, Stauder, R, Kuehr, T, Lang, A, Machherndl-Spandl, S, Mayrbaeurl, B, Noesslinger, T, Petzer, A, Valent, P, Greil, R, Thaler, J.
Leuk Lymphoma. 2018, 59(5):1121-1126.
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2017
T cell exhaustion: from pathophysiological basics to tumor immunotherapy.
Catakovic, K, Klieser, E, Neureiter, D, Geisberger, R.
Cell Commun Signal. 2017, 15(1):.
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Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signaling.
Aberger, F, Hutterer, E, Sternberg, C, Del Burgo, PJ, Hartmann, TN.
Cell Commun Signal. 2017, 15(1): 8.
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A phase 2 study of rituximab plus lenalidomide for mucosa-associated lymphoid tissue lymphoma.
Kiesewetter, B, Willenbacher, E, Willenbacher, W, Egle, A, Neumeister, P, Voskova, D, Mayerhoefer, ME, Simonitsch-Klupp, I, Melchardt, T, Greil, R, Raderer, M.
Blood. 2017, 129(3):383-385.
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Reactivation of dormant anti-tumor immunity - a clinical perspective of therapeutic immune checkpoint modulation.
Greil, R, Hutterer, E, Hartmann, TN, Pleyer, L.
Cell Commun Signal. 2017, 15(1): 5.
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Hemeoxygenase-1 as a Novel Driver in Ritonavir-Induced Insulin Resistance in HIV-1-Infected Patients.
Taylor, N, Kremser, I, Auer, S, Hoermann, G, Greil, R, Haschke-Becher, E, Esterbauer, H, Kenner, L, Oberkofler, H.
J Acquir Immune Defic Syndr. 2017, 75(1):e13-e20.
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The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation.
Wolff, F, Leisch, M, Greil, R, Risch, A, Pleyer, L.
Cell Commun Signal. 2017, 15(1):13.
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Olaptesed pegol, an anti-CXCL12/SDF-1 Spiegelmer, alone and with bortezomib-dexamethasone in relapsed/refractory multiple myeloma: a Phase IIa Study.
Ludwig, H, Weisel, K, Petrucci, MT, Leleu, X, Cafro, AM, Garderet, L, Leitgeb, C, Foa, R, Greil, R, Yakoub-Agha, I, Zboralski, D, Vauleon, S, Duemmler, T, Beyer, D, Kruschinski, A, Riecke, K, Baumann, M, Engelhardt, M.
Leukemia. 2017, 31(4):997-1000.
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Influence of body mass index on survival in indolent and mantle cell lymphomas: analysis of the StiL NHL1 trial.
Weiss, L, Melchardt, T, Egle, A, Hopfinger, G, Hackl, H, Greil, R, Barth, J, Rummel, M.
Ann Hematol. 2017.
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Azacitidine for Front-Line Therapy of Patients with AML: Reproducible Efficacy Established by Direct Comparison of International Phase 3 Trial Data with Registry Data from the Austrian Azacitidine Registry of the AGMT Study Group
Pleyer, L, Dohner, H, Dombret, H, Seymour, JF, Schuh, AC, Beach, CL, Swern, AS, Burgstaller, S, Stauder, R, Girschikofsky, M, Sill, H, Schlick, K, Thaler, J, Halter, B, Spandl, SM, Zebisch, A, Pichler, A, Pfeilstocker, M, Autzinger, EM, Lang, A, Geissler, K, Voskova, D, Sperr, WR, Hojas, S, Rogulj, IM, Andel, J, Greil, R.
INT J MOL SCI. 2017, 18(2): 415.
Milestones in Chronic Lymphocytic Leukemia: An exciting decade of progress-10th anniversary of memo.
Egle, A.
Memo. 2017, 10(1):8-12.
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Neoadjuvant Chemotherapy with Capecitabine, Oxaliplatin and Bevacizumab Followed by Concomitant Chemoradiation and Surgical Resection in Locally Advanced Rectal Cancer with High Risk of Recurrence - A Phase II Study.
Eisterer, W, Piringer, G, De Vries, A, Ofner, D, Greil, R, Tschmelitsch, J, Samonigg, H, Solkner, L, Gnant, M, Thaler, J.
Anticancer Res. 2017, 37(5):2683-2691.
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The Human NADPH Oxidase, Nox4, Regulates Cytoskeletal Organization in Two Cancer Cell Lines, HepG2 and SH-SY5Y.
Auer, S, Rinnerthaler, M, Bischof, J, Streubel, MK, Breitenbach-Koller, H, Geisberger, R, Aigner, E, Cadamuro, J, Richter, K, Sopjani, M, Haschke-Becher, E, Felder, TK, Breitenbach, M.
Front Oncol. 2017, 7:111.
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Ristocetin-induced platelet aggregation for monitoring of bleeding tendency in CLL treated with ibrutinib.
Kazianka, L, Drucker, C, Skrabs, C, Thomas, W, Melchardt, T, Struve, S, Bergmann, M, Staber, PB, Porpaczy, E, Einberger, C, Heinz, M, Hauswirth, A, Raderer, M, Pabinger, I, Thalhammer, R, Egle, A, Wendtner, CM, Follows, G, Hoermann, G, Quehenberger, P, Jilma, B, Jaeger, U.
Leukemia. 2017, 31(5):1117-1122.
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Amb a 1 isoforms: unequal siblings with distinct immunological features.
Wolf, M, Twaroch, TE, Huber, S, Reithofer, M, Steiner, M, Aglas, L, Hauser, M, Aloisi, I, Asam, C, Hofer, H, Parigiani, MA, Ebner, C, Bohle, B, Briza, P, Angela, N, Stolz, F, Jahn-Schmid, B, Wallner, M, Ferreira, F.
Allergy. 2017.
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Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study
Almeida, AM, Prebet, T, Itzykson, R, Ramos, F, Al-Ali, H, Shammo, J, Pinto, R, Maurillo, L, Wetzel, J, Musto, P, Van De Loosdrecht, AA, Costa, MJ, Esteves, S, Burgstaller, S, Stauder, R, Autzinger, EM, Lang, A, Krippl, P, Geissler, D, Falantes, JF, Pedro, C, Bargay, J, Deben, G, Garrido, A, Bonanad, S, Diez-Campelo, M, Thepot, S, Ades, L, Sperr, WR, Valent, P, Fenaux, P, Sekeres, MA, Greil, R, Pleyer, L.
INT J MOL SCI. 2017, 18(4): 837.
Differences in stem cell processing lead to distinct secretomes secretion - implications for differential results of previous clinical trials of stem cell therapy for myocardial infarction.
Wernly, B, Gonçalves, I, Kiss, A, Paar, V, Mösenlechner, T, Leisch, M, Santer, D, Motloch, L, Klein, KU, Tretter, EV, Kretzschmar, D, Podesser, B, Jung, C, Hoppe, UC, Lichtenauer, M.
Biotechnol J. 2017.
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The influence of FCGR2A and FCGR3A polymorphisms on the survival of patients with recurrent or metastatic squamous cell head and neck cancer treated with cetuximab.
Magnes, T, Melchardt, T, Hufnagl, C, Weiss, L, Mittermair, C, Neureiter, D, Klieser, E, Rinnerthaler, G, Roesch, S, Gaggl, A, Greil, R, Egle, A.
Pharmacogenomics J. 2017.
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Prognostic score in patients with recurrent or metastatic carcinoma of the head and neck treated with cetuximab and chemotherapy.
Magnes, T, Melchardt, T, Weiss, L, Mittermair, C, Neureiter, D, Klieser, E, Gampenrieder, S, Moser, G, Gaggl, A, Greil, R, Egle, A.
PLoS One. 2017, 12(7):e0180995.
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The Human NADPH Oxidase, Nox4, Regulates Cytoskeletal Organization in Two Cancer Cell Lines, HepG2 and SH-SY5Y.
Auer, S, Rinnerthaler, M, Bischof, J, Streubel, MK, Breitenbach-Koller, H, Geisberger, R, Aigner, E, Cadamuro, J, Richter, K, Sopjani, M, Haschke-Becher, E, Felder, TK, Breitenbach, M,
Front Oncol. 2017, 7: 111.
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Neoadjuvant Chemotherapy with Capecitabine, Oxaliplatin and Bevacizumab Followed by Concomitant Chemoradiation and Surgical Resection in Locally Advanced Rectal Cancer with High Risk of Recurrence - A Phase II Study.
Eisterer, W, Piringer, G, De Vries, A, Ofner, D, Greil, R, Tschmelitsch, J, Samonigg, H, Solkner, L, Gnant, M, Thaler, J.
Anticancer Res. 2017, 37(5):2683-2691.
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SABCS 2016: systemic therapy for metastatic breast cancer.
Gampenrieder, SP, Rinnerthaler, G, Greil, R.
MEMO-MAG EUR MED ONC. 2017, 10(2): 86-89.
Lenalidomide Maintenance Compared With Placebo in Responding Elderly Patients With Diffuse Large B-Cell Lymphoma Treated With First-Line Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone.
nnerthaler, G, Romeder, F, M.
J Clin Oncol. 2017, 35(22):2473-2481.
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Endothelin-1 genetic polymorphism as predictive marker for bevacizumab in metastatic breast cancer.
Gampenrieder, SP, Hufnagl, C, Brechelmacher, S, Huemer, F, Hackl, H, Rinnerthaler, G, Romeder, F, Monzo Fuentes, C, Morre, P, Hauser-Kronberger, C, Mlineritsch, B, Greil, R.
Pharmacogenomics J. 2017, 17(4):344-350.
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Red blood cell alloimmunization in 184 patients with myeloid neoplasms treated with azacitidine - A retrospective single center experience.
Leisch, M, Weiss, L, Lindlbauer, N, Jungbauer, C, Egle, A, Rohde, E, Greil, R, Grabmer, C, Pleyer, L.
Leuk Res. 2017, 59:12-19.
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COL7A1 Editing via CRISPR/Cas9 in Recessive Dystrophic Epidermolysis Bullosa.
Hainzl, S, Peking, P, Kocher, T, Murauer, EM, Larcher, F, Del Rio, M, Duarte, B, Steiner, M, Klausegger, A, Bauer, JW, Reichelt, J, Koller, U.
Mol Ther. 2017.
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Azacitidine in adult patients with acute myeloid leukemia.
Schuh, AC, Dohner, H, Pleyer, L, Seymour, JF, Fenaux, P, Dombreth, H.
Crit Rev Oncol Hematol. 2017, 116:159-177.
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Reactivation of dormant anti-tumor immunity - a clinical perspective of therapeutic immune checkpoint modulation.
Greil, R, Hutterer, E, Hartmann, TN, Pleyer, L.
Cell Commun Signal. 2017, 15(1):5.
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Endothelin-1 genetic polymorphism as predictive marker for bevacizumab in metastatic breast cancer.
Gampenrieder, SP, Hufnagl, C, Brechelmacher, S, Huemer, F, Hackl, H, Rinnerthaler, G, Romeder, F, Monzo Fuentes, C, Morre, P, Hauser-Kronberger, C, Mlineritsch, B, Greil, R.
Pharmacogenomics J. 2017, 17(4):344-350.
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Improvement of quality of life and psychological distress after inpatient cancer rehabilitation.
Riedl, D, Giesinger, JM, Wintner, LM, Loth, FL, Rumpold, G, Greil, R, Nickels, A, Licht, T, Holzner, B.
WIEN KLIN WOCHENSCHR. 2017, 129(19-20): 692-701.
Distribution and Metabolism of Lipocurc™ (Liposomal Curcumin) in Dog and Human Blood Cells: Species Selectivity and Pharmacokinetic Relevance.
Bolger, GT, Licollari, A, Tan, AM, Greil, R, Vcelar, B, Majeed, M, Helson, L.
ANTICANCER RES. 2017, 37(7): 3483-3492.
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When the guardian sleeps: Reactivation of the p53 pathway in cancer.
Merkel, O, Taylor, N, Prutsch, N, Staber, PB, Moriggl, R, Turner, SD, Kenner, L.
Mutat Res. 2017, 773:1-13.
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Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy.
Machado, Y, Duinkerken, S, Hoepflinger, V, Mayr, M, Korotchenko, E, Kurtaj, A, Pablos, I, Steiner, M, Stoecklinger, A, Lübbers, J, Schmid, M, Ritter, U, Scheiblhofer, S, Ablinger, M, Wally, V, Hochmann, S, Raninger, AM, Strunk, D, van Kooyk, Y, Thalhamer, J, Weiss, R.
J Control Release. 2017, 266:87-99.
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The first meeting of the Austrian Expert Panel for Molecular Cancer Profiling.
Seeber, A, Gastl, G, Eisterer, W, Gampenrieder, SP, Gerger, A, Kieler, M, Pichler, M, Prager, GW, Untergasser, G, Weltermann, A, Greil, R.
MEMO-MAG EUR MED ONC. 2017, 10(4): 255-258.
Update on squamous cell carcinoma of the head and neck: ASCO annual meeting 2017.
Magnes, T, Egle, A, Greil, R, Melchardt, T.
Memo. 2017, 10(4):220-223.
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ASCO 2017-highlights of gynecological cancer.
Radl, B, Mlineritsch, B.
Memo. 2017, 10(4):237-239.
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ASCO 2017-making a difference in cancer care with you.
Rinnerthaler, G.
MEMO-MAG EUR MED ONC. 2017, 10(4): 187-189.
Multiple myeloma of the mandibular condyle: a rare presentation.
Bottini, GB, Steiner, C, Melchardt, T, Gaggl, A.
Br J Oral Maxillofac Surg. 2017, 55(10):1046-1047.
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ASCO-update: gastrointestinal tumors.
Weiss, L, Huemer, F, Greil, R.
Memo. 2017, 10(4):240-243.
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Oxaliplatin/Irinotecan/Bevacizumab Followed by Docetaxel/Bevacizumab in Inoperable Locally Advanced or Metastatic Gastric Cancer Patients - AGMT_GASTRIC-3.
Wöll, E, Thaler, J, Keil, F, Gruenberger, B, Hejna, M, Eisterer, W, Fridrik, MA, Ulmer, H, Trommet, V, Huemer, F, Weiss, L, Greil, R.
Anticancer Res. 2017, 37(10):5553-5558.
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Comparison of Kaposi Sarcoma Risk in Human Immunodeficiency Virus-Positive Adults Across 5 Continents: A Multiregional Multicohort Study.
Rohner, E, Bütikofer, L, Schmidlin, K, Sengayi, M, Maskew, M, Giddy, J, Garone, D, Moore, RD, D’Souza, G, Goedert, JJ, Achenbach, C, Gill, MJ, Kitahata, MM, Patel, P, Silverberg, MJ, Castilho, J, McGowan, C, Chen, YA, Law, M, Taylor, N, Paparizos, V, Bonnet, F, Verbon, A, Fätkenheuer, G, Post, FA, Sabin, C, Mocroft, A, Moing, VL, Dronda, F, Obel, N, Grabar, S, Spagnuolo, V, Antinori, A, Quiros-Roldan, E, Mussini, C, Miro, JM, Meyer, L, Hasse, B, Konopnicki, D, Roca, B, Barger, D, Raben, D, Clifford, GM, Franceschi, S, Brockmeyer, N, Chakraborty, R, Egger, M, Bohlius, J.
Clin Infect Dis. 2017, 65(8):-1326.
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Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity.
Wolf, M, Aglas, L, Twaroch, TE, Steiner, M, Huber, S, Hauser, M, Parigiani, MA, Hofer, H, Ebner, C, Bohle, B, Briza, P, Neubauer, A, Stolz, F, Wallner, M, Ferreira, F.
J Allergy Clin Immunol. 2017.
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2016
miR-16-5p Is a Stably-Expressed Housekeeping MicroRNA in Breast Cancer Tissues from Primary Tumors and from Metastatic Sites.
Rinnerthaler, G, Hackl, H, Gampenrieder, SP, Hamacher, F, Hufnagl, C, Hauser-Kronberger, C, Zehentmayr, F, Fastner, G, Sedlmayer, F, Mlineritsch, B, Greil, R.
Int J Mol Sci. 2016, 17(2).
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DPYD Genotyping to Predict Adverse Events Following Treatment With Flourouracil-Based Adjuvant Chemotherapy in Patients With Stage III Colon Cancer: A Secondary Analysis of the PETACC-8 Randomized Clinical Trial.
Boige, V, Vincent, M, Alexandre, P, Tejpar, S, Landolfi, S, Le Malicot, K, Greil, R, Cuyle, PJ, Yilmaz, M, Faroux, R, Matzdorff, A, Salazar, R, Lepage, C, Taieb, J, Laurent-Puig, P.
JAMA Oncol. 2016, xx.
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Bleomycin in older early-stage favorable Hodgkin lymphoma patients: analysis of the German Hodgkin Study Group (GHSG) HD10 and HD13 trials.
Böll, B, Goergen, H, Behringer, K, Bröckelmann, PJ, Hitz, F, Kerkhoff, A, Greil, R, von Tresckow, B, Eichenauer, DA, Bürkle, C, Borchmann, S, Fuchs, M, Diehl, V, Engert, A, Borchmann, P.
Blood. 2016, 127(18):2189-2192.
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Low Beclin-1 expression predicts improved overall survival in patients treated with immunomodulatory drugs for multiple myeloma and identifies autophagy inhibition as a promising potentially druggable new therapeutic target: an analysis from The Austrian Myeloma Registry (AMR).
Willenbacher, W, Thangavadivel, S, Greil, R, Willenbacher, E, Weger, R, Manzl, C, Jöhrer, K, Brunner, A.
Leuk Lymphoma. 2016, xx: -12.
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Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones.
Melchardt, T, Hufnagl, C, Weinstock, DM, Kopp, N, Neureiter, D, Tränkenschuh, W, Hackl, H, Weiss, L, Rinnerthaler, G, Hartmann, TN, Greil, R, Weigert, O, Egle, A.
Oncotarget. 2016.
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Endothelin-1 genetic polymorphism as predictive marker for bevacizumab in metastatic breast cancer.
Gampenrieder, SP, Hufnagl, C, Brechelmacher, S, Huemer, F, Hackl, H, Rinnerthaler, G, Romeder, F, Monzo Fuentes, C, Morre, P, Hauser-Kronberger, C, Mlineritsch, B, Greil, R.
Pharmacogenomics J. 2016.
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A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study.
Rawstron, AC, Fazi, C, Agathangelidis, A, Villamor, N, Letestu, R, Nomdedeu, J, Palacio, C, Stehlikova, O, Kreuzer, KA, Liptrot, S, O"Brien, D, de Tute, RM, Marinov, I, Hauwel, M, Spacek, M, Dobber, J, Kater, AP, Gambell, P, Soosapilla, A, Lozanski, G, Brachtl, G, Lin, K, Boysen, J, Hanson, C, Jorgensen, JL, Stetler-Stevenson, M, Yuan, C, Broome, HE, Rassenti, L, Craig, F, Delgado, J, Moreno, C, Bosch, F, Egle, A, Doubek, M, Pospisilova, S, Mulligan, S, Westerman, D, Sanders, CM, Emerson, R, Robins, HS, Kirsch, I, Shanafelt, T, Pettitt, A, Kipps, TJ, Wierda, WG, Cymbalista, F, Hallek, M, Hillmen, P, Montserrat, E, Ghia, P.
Leukemia. 2016, 30(4):929-936.
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Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors.
Ganghammer, S, Gutjahr, J, Hutterer, E, Krenn, PW, Pucher, S, Zelle-Rieser, C, Jöhrer, K, Wijtmans, M, Leurs, R, Smit, MJ, Gattei, V, Greil, R, Hartmann, TN.
Haematologica. 2016, 101(3):e99-e102.
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Cardiotoxicity with rituximab, cyclophosphamide, non-pegylated liposomal doxorubicin, vincristine and prednisolone compared to rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone in frontline treatment of patients with diffuse large B-cell lymphoma: A randomised phase-III study from the Austrian Cancer Drug Therapy Working Group [Arbeitsgemeinschaft Medikamentöse Tumortherapie AGMT](NHL-14).
Fridrik, MA, Jaeger, U, Petzer, A, Willenbacher, W, Keil, F, Lang, A, Andel, J, Burgstaller, S, Krieger, O, Oberaigner, W, Sihorsch, K, Greil, R.
Eur J Cancer. 2016, 58:112-121.
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Elevated Toll-Like Receptor-Induced CXCL8 Secretion in Human Blood Basophils from Allergic Donors Is Independent of Toll-Like Receptor Expression Levels.
Steiner, M, Hawranek, T, Schneider, M, Ferreira, F, Horejs-Hoeck, J, Harrer, A, Himly, M.
PLoS One. 2016, 11(2):e0149275.
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The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells.
Hofbauer, SW, Krenn, PW, PiГ±ПЊn Hofbauer, J, Pucher, S, Asslaber, D, Egle, A, Hartmann, TN, Greil, R.
Br J Haematol. 2016, 172(5): 815-819.
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ILK Induction in Lymphoid Organs by a TNFО±-NF-ОєB-Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia.
Krenn, PW, Hofbauer, SW, Pucher, S, Hutterer, E, Hinterseer, E, Denk, U, Asslaber, D, Ganghammer, S, Sternberg, C, Neureiter, D, Aberger, F, Wickström, SA, Egle, A, Greil, R, Hartmann, TN.
Cancer Res. 2016, 76(8):2186-2196.
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The clinical significance of fibrinogen plasma levels in patients with diffuse large B cell lymphoma.
Troppan, KT, Melchardt, T, Wenzl, K, Schlick, K, Deutsch, A, Bullock, MD, Reitz, D, Beham-Schmid, C, Weiss, L, Neureiter, D, Tränkenschuh, W, Greil, R, Neumeister, P, Egle, A, Pichler, M.
J Clin Pathol. 2016, 69(4):326-330.
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A diagnostic algorithm for the detection of inhibitors against coagulation Factor V.
Cadamuro, J, Skocic, M, Meisl, B, Raggam, RB, Felder, TK, PrГјller, F, Reinstadler, K, Wiedemann, H, Mrazek, C.
Clin Chem Lab Med. 2016, 54(7):e203-e206.
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Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo.
Hanna, BS, McClanahan, F, Yazdanparast, H, Zaborsky, N, Kalter, V, Rößner, PM, Benner, A, Dürr, C, Egle, A, Gribben, JG, Lichter, P, Seiffert, M.
Leukemia. 2016, 30(3): 570-579.
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Standardization of allergen products: 2. Detailed characterization of GMP-produced recombinant Phl p 5.0109 as European Pharmacopoeia reference standard.
Himly, M, Nandy, A, Kahlert, H, Thilker, M, Steiner, M, Briza, P, Neubauer, A, Klysner, S, van Ree, R, Buchheit, KH, Vieths, S, Ferreira, F,f.
Allergy. 2016, 71(4):49-504.
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Fluorouracil and Dihydropyrimidine Dehydrogenase Genotyping.
Magnes, T, Melchardt, T, Weiss, L, Hufnagl, C, Greil, R, Egle, A.
J Clin Oncol. 2016.
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Persistent CD49d engagement in circulating CLL cells: a role for blood-borne ligands?.
Benedetti, D, Tissino, E, Caldana, C, Dal Bo, M, Bomben, R, Marconi, D, Ganghammer, S, Zaja, F, Pozzato, G, Di Raimondo, F, Hartmann, TN, Del Poeta, G, VanMeter, A, Zucchetto, A, Espina, V, Liotta, L, Gattei, V.
Leukemia. 2016, 30(2): 513-517.
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Bleomycin in older early-stage favorable Hodgkin lymphoma patients: analysis of the German Hodgkin Study Group (GHSG) HD10 and HD13 trials.
Böll, B, Goergen, H, Behringer, K, Bröckelmann, PJ, Hitz, F, Kerkhoff, A, Greil, R, von Tresckow, B, Eichenauer, DA, Bürkle, C, Borchmann, S, Fuchs, M, Diehl, V, Engert, A, Borchmann, P.
Blood. 2016, 127(18):2189-2192.
View this publication in the PUBMED database
Fluorouracil and Dihydropyrimidine Dehydrogenase Genotyping.
Magnes, T, Melchardt, T, Weiss, L, Hufnagl, C, Greil, R, Egle, A,.
J Clin Oncol. 2016, 34(20):2433-2434.
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FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis.
Suker, M, Beumer, BR, Sadot, E, Marthey, L, Faris, JE, Mellon, EA, El-Rayes, BF, Wang-Gillam, A, Lacy, J, Hosein, PJ, Moorcraft, SY, Conroy, T, Hohla, F, Allen, P, Taieb, J, Hong, TS, Shridhar, R, Chau, I, van Eijck, CH, Koerkamp, BG.
Lancet Oncol. 2016, 17(6):801-810.
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CD1d expression on chronic lymphocytic leukemia B cells affects disease progression and induces T cell skewing in CD8 positive and CD4CD8 double negative T cells.
Zaborsky, N, Gassner, FJ, Asslaber, D, Reinthaler, P, Denk, U, Flenady, S, Hofbauer, JP, Danner, B, Rebhandl, S, Harrer, A, Geisberger, R, Greil, R, Egle, A.
Oncotarget. 2016.
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Adjuvant medical treatment for breast cancer in elderly and old women.
Westphal, T, Rinnerthaler, G, Mlineritsch, B.
MEMO-MAG EUR MED ONC. 2016, 9(1): 17-19.
Immune checkpoint blockade in ovarian cancer.
Weiss, L, Huemer, F, Mlineritsch, B, Greil, R.
Memo. 2016, 9:82-84.
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Azacitidine front-line in 339 patients with myelodysplastic syndromes and acute myeloid leukaemia: comparison of French-American-British and World Health Organization classifications.
Pleyer, L, Burgstaller, S, Stauder, R, Girschikofsky, M, Sill, H, Schlick, K, Thaler, J, Halter, B, Machherndl-Spandl, S, Zebisch, A, Pichler, A, Pfeilstocker, M, Autzinger, EM, Lang, A, Geissler, K, Voskova, D, Geissler, D, Sperr, WR, Hojas, S, Rogulj, IM, Andel, J, Greil, R.
J Hematol Oncol. 2016, 9:39.
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Bcl-2 proteins in development, health, and disease of the hematopoietic system.
Kollek, M, MГјller, A, Egle, A, Erlacher, M.
FEBS J. 2016, 283(15):2779-2810.
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CDK4/6 inhibition in luminal breast cancer.
Gampenrieder, SP, Rinnerthaler, G, Greil, R.
MEMO-MAG EUR MED ONC. 2016, 9(2): 76-81.
CRISPR/Cas9-mediated gene repair in the COL7A1 gene.
Prochazka, KT, Melchardt, T, Posch, F, Schlick, K, Deutsch, A, Beham-Schmid, C, Weiss, L, Gary, T, Neureiter, D, Klieser, E, Greil, R, Neumeister, P, Egle, A, Pichler, M.
Br J Cancer. 2016.
Evaluation of the immunogenicity of viral epitopes in a cancer immunogene therapy approach for squamous cell carcinoma in RDEB.
Gampenrieder, SP, Hufnagl, C, Brechelmacher, S, Huemer, F, Hackl, H, Rinnerthaler, G, Romeder, F, Monzo Fuentes, C, Morre, P, Hauser-Kronberger, C, Mlineritsch, B, Greil, R.
Pharmacogenomics J. 2016.
Targeting tumor metabolism in the therapy of aggressive squamous cell carcinoma in patients with epidermolysis bullosa.
Boige, V, Vincent, M, Alexandre, P, Tejpar, S, Landolfi, S, Le Malicot, K, Greil, R, Cuyle, PJ, Yilmaz, M, Faroux, R, Matzdorff, A, Salazar, R, Lepage, C, Taieb, J, Laurent-Puig, P.
JAMA Oncol. 2016.
Combining antisense molecules with splicing modulation for KRT14 repair in epidermolysis bullosa.
Willenbacher, W, Thangavadivel, S, Greil, R, Willenbacher, E, Weger, R, Manzl, C, Jöhrer, K, Brunner, A.
Leuk Lymphoma. 2016, 57(10):2330-2341.
Developing a cancer immunogene therapy approach for Epidermolysis bullosa-associated squamous cell carcinoma.
Melchardt, T, Hufnagl, C, Weinstock, DM, Kopp, N, Neureiter, D, Tränkenschuh, W, Hackl, H, Weiss, L, Rinnerthaler, G, Hartmann, TN, Greil, R, Weigert, O, Egle, A.
Oncotarget. 2016.
An international, multicenter, prospective, observational study of neutropenia in patients being treated with lenalidomide + dexamethasone for relapsed or relapsed/refractory multiple myeloma (RR-MM).
Kollek, M, MГјller, A, Egle, A, Erlacher, M.
FEBS J. 2016, 283(15):2779-2810.
Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic HematopoiesisMasters of Survival and Clonality?.
Zaborsky, N, Gassner, FJ, Asslaber, D, Reinthaler, P, Denk, U, Flenady, S, Hofbauer, JP, Danner, B, Rebhandl, S, Harrer, A, Geisberger, R, Greil, R, Egle, A.
Oncotarget. 2016.
Bevacizumab plus paclitaxel versus bevacizumab plus capecitabine as first-line treatment for HER2-negative metastatic breast cancer (TURANDOT): primary endpoint results of a randomised, open-label, non-inferiority, phase 3 trial.
Greil, R, ObrtlГkovГЎ, P, Smolej, L, KozГЎk, T, Steurer, M, Andel, J, Burgstaller, S, MikuЕЎkovГЎ, E, Gercheva, L, NГ¶sslinger, T, PapajГk, T, LadickГЎ, M, Girschikofsky, M, HrubiЕЎko, M, JГ¤ger, U, Fridrik, M, Pecherstorfer, M, KrГЎlikovГЎ, E, Burcoveanu, C, Spasov, E, Petzer, A, Mihaylov, G, Raynov, J, Oexle, H, Zabernigg, A, FlochovГЎ, E, PalГЎЕЎthy, S, StehlГkovГЎ, O, Doubek, M, Altenhofer, P, Pleyer, L, Melchardt, T, Klingler, A, Mayer, J, Egle, A.
Lancet Haematol. 2016, 3(7):e317-e329.
Ibrutinib Inhibits VLA-4-Dependent Adhesion in CLL-Letter.
Rinnerthaler, G, Hackl, H, Gampenrieder, SP, Hamacher, F, Hufnagl, C, Hauser-Kronberger, C, Zehentmayr, F, Fastner, G, Sedlmayer, F, Mlineritsch, B, Greil, R.
Int J Mol Sci. 2016, 17(2).
Assessment of Pharmacokinetic Interaction Between Capecitabine and Cetuximab in Metastatic Colorectal Cancer Patients.
Steiner, M, Harrer, A, Himly, M.
Front Pharmacol. 2016, 7:171.
NCCN-IPI score-independent prognostic potential of pretreatment uric acid levels for clinical outcome of diffuse large B-cell lymphoma patients.
Benedetti, D, Tissino, E, Caldana, C, Dal Bo, M, Bomben, R, Marconi, D, Ganghammer, S, Zaja, F, Pozzato, G, Di Raimondo, F, Hartmann, TN, Del Poeta, G, VanMeter, A, Zucchetto, A, Espina, V, Liotta, L, Gattei, V.
Leukemia. 2016, 30(2): 513-517.
CD44: More than a mere stem cell marker.
Morath, I, Hartmann, TN, Orian-Rousseau, V.
Int J Biochem Cell Biol. 2016.
Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.
Shatirishvili, M, Burk, AS, Franz, CM, Pace, G, Kastilan, T, Breuhahn, K, Hinterseer, E, Dierich, A, Bakiri, L, Wagner, EF, Ponta, H, Hartmann, TN, Tanaka, M, Orian-Rousseau, V.
Cell Death Dis. 2016, 7(11):e2461.
Intermittent low-dose bevacizumab in hereditary hemorrhagic telangiectasia : A case report.
Huemer, F, Dejaco, M, Grabmer, C, Melchardt, T, Neureiter, D, Mayer, G, Egle, A, Greil, R, Weiss, L.
Wien Klin Wochenschr. 2016.
Hemeoxygenase-1 as a novel driver in ritonavir-induced insulin resistance in HIV-1-infected patients.
Taylor, N, Kremser, I, Auer, S, Hoermann, G, Greil, R, Haschke-Becher, E, Esterbauer, H, Kenner, L, Oberkofler, H.
J Acquir Immune Defic Syndr. 2016.
BCR and chemokine responses upon anti-IgM and anti-IgD stimulation in chronic lymphocytic leukaemia.
Haerzschel, A, Catusse, J, Hutterer, E, Paunovic, M, Zirlik, K, Eibel, H, Krenn, PW, Hartmann, TN, Burger, M.
Ann Hematol. 2016, 95(12):197-1988.
Panitumumab-Associated Encephalopathy after Accidental Intra-arterial Application through Dislocated Central Venous Access Device.
Pikija, S, Pilz, G, Gschwandtner, G, Rösler, C, Schlick, K, Greil, R, Sellner, J.
Front Neurol. 2016, 7:196.
Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis -Masters of Survival and Clonality?.
Pleyer, L, Valent, P, Greil, R.
INT J MOL SCI. 2016, 17(7): 1009.
View this publication in the PUBMED database
Fluorouracil and Dihydropyrimidine Dehydrogenase Genotyping.
Magnes, T, Melchardt, T, Weiss, L, Hufnagl, C, Greil, R, Egle, A.
J Clin Oncol. 2016, 34(20): 2433-2434.
View this publication in the PUBMED database
Azacitidine front-line in 339 patients with myelodysplastic syndromes and acute myeloid leukaemia: comparison of French-American-British and World Health Organization classifications.
Pleyer, L, Burgstaller, S, Stauder, R, Girschikofsky, M, Sill, H, Schlick, K, Thaler, J, Halter, B, Machherndl-Spandl, S, Zebisch, A, Pichler, A, Pfeilstöcker, M, Autzinger, EM, Lang, A, Geissler, K, Voskova, D, Geissler, D, Sperr, WR, Hojas, S, Rogulj, IM, Andel, J, Greil, R.
J HEMATOL ONCOL. 2016, 9: 39.
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Elevated Toll-Like Receptor-Induced CXCL8 Secretion in Human Blood Basophils from Allergic Donors Is Independent of Toll-Like Receptor Expression Levels.
Steiner, M, Hawranek, T, Schneider, M, Ferreira, F, Horejs-Hoeck, J, Harrer, A, Himly, M.
PLOS ONE. 2016, 11(2): e0149275.
View this publication in the PUBMED database
An international, multicenter, prospective, observational study of neutropenia in patients being treated with lenalidomide?+?dexamethasone for relapsed or relapsed/refractory multiple myeloma (RR-MM).
Leleu, X, Terpos, E, Sanz, RG, Cooney, J, O"Gorman, P, Minarik, J, Greil, R, Williams, C, Gray, D, Szabo, Z.
AM J HEMATOL. 2016, 91(8): 806-811.
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Assessment of Pharmacokinetic Interaction Between Capecitabine and Cetuximab in Metastatic Colorectal Cancer Patients.
Rachar, V, Czejka, M, Kitzmueller, M, Buchner, P, Lichtneckert, M, Greil, R, Geiler, H, Dittrich, C.
ANTICANCER RES. 2016, 36(9): 4715-4723.
View this publication in the PUBMED database
CD44: More than a mere stem cell marker.
Morath, I, Hartmann, TN, Orian-Rousseau, V.
Int J Biochem Cell Biol. 2016.
View this publication in the PUBMED database
Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.
Shatirishvili, M, Burk, AS, Franz, CM, Pace, G, Kastilan, T, Breuhahn, K, Hinterseer, E, Dierich, A, Bakiri, L, Wagner, EF, Ponta, H, Hartmann, TN, Tanaka, M, Orian-Rousseau, V.
Cell Death Dis. 2016, 7(11):e2461.
View this publication in the PUBMED database
NCCN-IPI score-independent prognostic potential of pretreatment uric acid levels for clinical outcome of diffuse large B-cell lymphoma patients.
Prochazka, KT, Melchardt, T, Posch, F, Schlick, K, Deutsch, A, Beham-Schmid, C, Weiss, L, Gary, T, Neureiter, D, Klieser, E, Greil, R, Neumeister, P, Egle, A, Pichler, M.
Br J Cancer. 2016, xx:.
View this publication in the PUBMED database
Hemeoxygenase-1 as a novel driver in ritonavir-induced insulin resistance in HIV-1-infected patients.
Taylor, N, Kremser, I, Auer, S, Hoermann, G, Greil, R, Haschke-Becher, E, Esterbauer, H, Kenner, L, Oberkofler, H.
J Acquir Immune Defic Syndr. 2016.
View this publication in the PUBMED database
BCR and chemokine responses upon anti-IgM and anti-IgD stimulation in chronic lymphocytic leukaemia.
Haerzschel, A, Catusse, J, Hutterer, E, Paunovic, M, Zirlik, K, Eibel, H, Krenn, PW, Hartmann, TN, Burger, M.
Ann Hematol. 2016, 95(12):197-1988.
View this publication in the PUBMED database
Panitumumab-Associated Encephalopathy after Accidental Intra-arterial Application through Dislocated Central Venous Access Device.
Pikija, S, Pilz, G, Gschwandtner, G, Rösler, C, Schlick, K, Greil, R, Sellner, J.
Front Neurol. 2016, 7:196.
View this publication in the PUBMED database
Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones.
Melchardt, T, Hufnagl, C, Weinstock, DM, Kopp, N, Neureiter, D, Tränkenschuh, W, Hackl, H, Weiss, L, Rinnerthaler, G, Hartmann, TN, Greil, R, Weigert, O, Egle, A.
Oncotarget. 2016, xx:.
View this publication in the PUBMED database
Bcl-2 proteins in development, health, and disease of the hematopoietic system.
Kollek, M, MГјller, A, Egle, A, Erlacher, M.
FEBS J. 2016, 283(15): 2779-2810.
View this publication in the PUBMED database
Basophil Reactivity as Biomarker in Immediate Drug Hypersensitivity Reactions-Potential and Limitations.
Steiner, M, Harrer, A, Himly, M.
Front Pharmacol. 2016, 7: 171.
View this publication in the PUBMED database
Rituximab maintenance versus observation alone in patients with chronic lymphocytic leukaemia who respond to first-line or second-line rituximab-containing chemoimmunotherapy: final results of the AGMT CLL-8a Mabtenance randomised trial.
Greil, R, ObrtlГkovГЎ, P, Smolej, L, KozГЎk, T, Steurer, M, Andel, J, Burgstaller, S, MikuЕЎkovГЎ, E, Gercheva, L, NГ¶sslinger, T, PapajГk, T, LadickГЎ, M, Girschikofsky, M, HrubiЕЎko, M, JГ¤ger, U, Fridrik, M, Pecherstorfer, M, KrГЎlikovГЎ, E, Burcoveanu, C, Spasov, E, Petzer, A, Mihaylov, G, Raynov, J, Oexle, H, Zabernigg, A, FlochovГЎ, E, PalГЎЕЎthy, S, StehlГkovГЎ, O, Doubek, M, Altenhofer, P, Pleyer, L, Melchardt, T, Klingler, A, Mayer, J, Egle, A.
Lancet Haematol. 2016, 3(7): e317-e329.
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2010 - 2015
Interessante PraМ€sentationen am europaМ€ischen Krebskongress: Neue Daten beim Mammakarzinom.
Gampenrieder, SP.
Spectrum Onkologie. 2015. 05: 34-36.
Response to comment by P. Vassilakopoulos and colleagues.
Jaeger, U, Praxmarer, M, Greil, R.
Haematologica. 2015, 100(11): e482.
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Anti-Hu Antibody Associated Paraneoplastic Cerebellar Degeneration in Head and Neck Cancer.
Huemer, F, Melchardt, T, Tränkenschuh, W, Neureiter, D, Moser, G, Magnes, T, Weiss, L, Schlattau, A, Hufnagl, C, Ricken, G, Höftberger, R, Greil, R, Egle, A.
BMC Cancer. 2015, 15:996.
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Ropeginterferon alfa-2b, a novel IFNО±-2b, induces high response rates with low toxicity in patients with polycythemia vera.
Gisslinger, H, Zagrijtschuk, O, Buxhofer-Ausch, V, Thaler, J, Schloegl, E, Gastl, GA, Wolf, D, Kralovics, R, Gisslinger, B, Strecker, K, Egle, A, Melchardt, T, Burgstaller, S, Willenbacher, E, Schalling, M, Them, NC, Kadlecova, P, Klade, C, Greil, R.
Blood. 2015, 126(15): 1762-1769.
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Independent Prognostic Value of Serum Markers in Diffuse Large B-Cell Lymphoma in the Era of the NCCN-IPI.
Melchardt, T, Troppan, K, Weiss, L, Hufnagl, C, Neureiter, D, Tränkenschuh, W, Schlick, K, Huemer, F, Deutsch, A, Neumeister, P, Greil, R, Pichler, M, Egle, A.
J Natl Compr Canc Netw. 2015, 13(12):1501-1508.
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Cytomegalovirus reactivation and its clinical impact in patients with solid tumors.
Schlick, K, Grundbichler, M, Auberger, J, Kern, JM, Hell, M, Hohla, F, Hopfinger, G, Greil, R.
INFECT AGENTS CANCER. 2015, 10:.
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Digging deep into "dirty" drugs - modulation of the methylation machinery.
Pleyer, L, Greil, R.
Drug Metab Rev. 2015, 47(2): 252-279.
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CYP39A1 polymorphism is associated with toxicity during intensive induction chemotherapy in patients with advanced head and neck cancer.
Melchardt, T, Hufnagl, C, Magnes, T, Weiss, L, Hutarew, G, Neureiter, D, Schlattau, A, Moser, G, Gaggl, A, Tränkenschuh, W, Greil, R, Egle, A.
BMC Cancer. 2015, 15:725.
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CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21.
Ganghammer, S, Hutterer, E, Hinterseer, E, Brachtl, G, Asslaber, D, Krenn, PW, Girbl, T, Berghammer, P, Geisberger, R, Egle, A, Zucchetto, A, Kruschinski, A, Gattei, V, Chigaev, A, Greil, R, Hartmann, TN.
Oncotarget. 2015, 6(14): 12048-12060.
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Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial.
Gnant, M, Pfeiler, G, Dubsky, PC, Hubalek, M, Greil, R, Jakesz, R, Wette, V, Balic, M, Haslbauer, F, Melbinger, E, Bjelic-Radisic, V, Artner-Matuschek, S, Fitzal, F, Marth, C, Sevelda, P, Mlineritsch, B, Steger, GG, Manfreda, D, Exner, R, Egle, D, Bergh, J, Kainberger, F, Talbot, S, Warner, D, Fesl, C, Singer, CF.
LANCET. 2015, 386(9992): 433-443.
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Chronic lymphocytic leukaemia induces an exhausted T cell phenotype in the TCL1 transgenic mouse model.
Gassner FJ, Zaborsky N, Catakovic K, Rebhandl S, Huemer M, Egle A, Hartmann TN, Greil R, Geisberger R.
Br J Haematol. 2015 Aug,170(4):515-22. doi: 10.1111/bjh.13467. Epub 2015 May 4.
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AIDing cancer treatment: Reducing AID activity via HSP90 inhibition.
Rebhandl, S, Geisberger, R.
Eur J Immunol. 2015, 45(8): 2208-2211.
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Identifying clinically relevant prognostic subgroups of postmenopausal women with node-positive hormone receptor-positive early-stage breast cancer treated with endocrine therapy: a combined analysis of ABCSG-8 and ATAC using the PAM50 risk of recurrence score and intrinsic subtype.
Gnant, M, Sestak, I, Filipits, M, Dowsett, M, Balic, M, Lopez-Knowles, E, Greil, R, Dubsky, P, Stoeger, H, Rudas, M, Jakesz, R, Ferree, S, Cowens, JW, Nielsen, T, Schaper, C, Fesl, C, Cuzick, J.
ANN ONCOL. 2015, 26(8): 1685-1691.
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Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2,5) translocation.
Merkel, O, Hamacher, F, Griessl, R, Grabner, L, Schiefer, AI, Prutsch, N, Baer, C, Egger, G, Schlederer, M, Krenn, PW, Hartmann, TN, Simonitsch-Klupp, I, Plass, C, Staber, PB, Moriggl, R, Turner, SD, Greil, R, Kenner, L.
J Pathol. 2015, 236(4): 44-56.
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[Therapie des Patienten mit Radioiod-refraktärem, differenziertem Schilddrüsenkarzinom. Ein Konsensusstatement].
Lindner, C, Dierneder, J, Pall, G, Pirich, C, Hoffmann, M, Raderer, M, Becherer, A, Niederle, B, Lipp, R, Lind, P, Gallowitsch, H, Romeder, F, Virgolini, I.
Nuklearmedizin. 2015, 54(3): 125-130.
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B-cell receptor usage correlates with the sensitivity to CD40 stimulation and the occurrence of CD4+ T-cell clonality in chronic lymphocytic leukemia.
Zaborsky, N, Holler, C, Geisberger, R, Asslaber, D, Gassner, FJ, Egger, V, PiГ±Гіn-Hofbauer, J, Kocher, T, Hartmann, TN, Greil, R, Egle, A.
Haematologica. 2015, 100(8): e307-e310.
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Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.
Kern, D, Regl, G, Hofbauer, SW, Altenhofer, P, Achatz, G, Dlugosz, A, Schnidar, H, Greil, R, Hartmann, TN, Aberger, F.
Oncogene. 2015, 34(42): 5341-5351.
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CD18 (ITGB2) expression in chronic lymphocytic leukaemia is regulated by DNA methylation-dependent and -independent mechanisms.
Hutterer, E, Asslaber, D, Caldana, C, Krenn, PW, Zucchetto, A, Gattei, V, Greil, R, Hartmann, TN.
Br J Haematol. 2015, 169(2):286-289.
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Molecular responses and chromosomal aberrations in patients with polycythemia vera treated with peg-proline-interferon alpha-2b.
Them, NC, Bagienski, K, Berg, T, Gisslinger, B, Schalling, M, Chen, D, Buxhofer-Ausch, V, Thaler, J, Schloegl, E, Gastl, GA, Wolf, D, Strecker, K, Egle, A, Melchardt, T, Burgstaller, S, Willenbacher, E, Zagrijtschuk, O, Klade, C, Greil, R, Gisslinger, H, Kralovics, R.
Am J Hematol. 2015, 90(4): 288-294.
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Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin"s lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K, Goergen, H, Hitz, F, Zijlstra, JM, Greil, R, Markova, J, Sasse, S, Fuchs, M, Topp, MS, Soekler, M, Mathas, S, Meissner, J, Wilhelm, M, Koch, P, Lindemann, H, Schalk, E, Semrau, R, Kriz, J, Vieler, T, Bentz, M, Lange, E, Mahlberg, R, Hassler, A, Vogelhuber, M, Hahn, D, Mezger, J, Krause, SW, Skoetz, N, Böll, B, von Tresckow, B, Diehl, V, Hallek, M, Borchmann, P, Stein, H, Eich, H, Engert, A.
Lancet. 2015, 385(9976):1418-1427.
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Zoledronic acid combined with adjuvant endocrine therapy of tamoxifen versus anastrozol plus ovarian function suppression in premenopausal early breast cancer: final analysis of the Austrian Breast and Colorectal Cancer Study Group Trial 12.
Gnant, M, Mlineritsch, B, Stoeger, H, Luschin-Ebengreuth, G, Knauer, M, Moik, M, Jakesz, R, Seifert, M, Taucher, S, Bjelic-Radisic, V, Balic, M, Eidtmann, H, Eiermann, W, Steger, G, Kwasny, W, Dubsky, P, Selim, U, Fitzal, F, Hochreiner, G, Wette, V, Sevelda, P, Ploner, F, Bartsch, R, Fesl, C, Greil, R.
Ann Oncol. 2015, 26(2):313-320.
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IOERT as anticipated tumor bed boost during breast-conserving surgery after neoadjuvant chemotherapy in locally advanced breast cancer-Results of a case series after 5-year follow-up.
Fastner, G, Reitsamer, R, Ziegler, I, Zehentmayr, F, Fussl, C, Kopp, P, Peintinger, F, Greil, R, Fischer, T, Deutschmann, H, Sedlmayer, F.
Int J Cancer. 2015, 136(5): 1193-1201.
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Lapatinib-plus-Pegylated Liposomal Doxorubicin in Advanced HER2-positive Breast Cancer Following Trastuzumab: A Phase II Trial.
Pircher, M, Mlineritsch, B, Fridrik, MA, Dittrich, C, Lang, A, Petru, E, Weltermann, A, Thaler, J, Hufnagl, C, Gampenrieder, SP, Rinnerthaler, G, Ressler, S, Ulmer, H, Greil, R.
Anticancer Res. 2015, 35(1): 517-521.
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A patient diagnosed with BRAF-mutated non-small cell lung cancer and hairy cell leukemia: at last, which entity is really carrying the BRAF mutation?.
Schlick, K, Troch, M, Placher-Sorko, G, Faber, V, Neureiter, D, Berghoff, AS, Preusser, M, Greil, R, Hopfinger, G.
Ann Hematol. 2015, 94(2): 345-346.
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Adipocyte-derived players in hematologic tumors: useful novel targets?.
Jöhrer, K, Ploner, C, Thangavadivel, S, Wuggenig, P, Greil, R.
Expert Opin Biol Ther. 2015, 15(1): 61-77.
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A phase 1 dose escalation study of BI 831266, an inhibitor of Aurora kinase B, in patients with advanced solid tumors.
Dittrich, C, Fridrik, MA, Koenigsberg, R, Lee, C, Goeldner, R, Hilbert, J, Greil, R.
Invest New Drugs. 2015, 33(2): 409-422.
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Relations of vitamin D status, gender and type 2 diabetes in middle-aged Caucasians.
Stadlmayr, A, Aigner, E, Huber-Schönauer, U, Niederseer, D, Zwerina, J, Husar-Memmer, E, Hohla, F, Schett, G, Patsch, W, Datz, C.
Acta Diabetol. 2015, 52(1):39-46.
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Treatment of aggressive B-cell lymphoma in elderly patients: influence of single nucleotide polymorphisms affecting pharmacodynamics of chemotherapeutics.
Melchardt, T, Weiss, L, Hufnagl, C, Neureiter, D, Kemmerling, R, Morre, P, Boekstegers, A, Hopfinger, G, Auberger, J, Steinkirchner, S, Pleyer, L, Greil, R, Egle, A.
Leuk Lymphoma. 2015, 56(2):353-360.
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Differential role of angiogenesis and tumour cell proliferation in brain metastases according to primary tumour type: analysis of 639 cases.
Berghoff, AS, Ilhan-Mutlu, A, Dinhof, C, Magerle, M, Hackl, M, Widhalm, G, Hainfellner, JA, Dieckmann, K, Pichler, J, Hutterer, M, Melchardt, T, Bartsch, R, Zielinski, CC, Birner, P, Preusser, M.
Neuropathol Appl Neurobiol. 2015, 41(2):e41-e55.
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VLA-4 and CXCR4 overexpression in bone marrow of an aleukemic B-cell acute lymphoblastic leukemia presenting with osteolytic bone lesions.
Hinterseer, E, Stiefel, O, Neureiter, D, Kandler, G, Vogt, S, Hutter, J, Strasser, G, Greil, R, Hartmann, TN, Hopfinger, G.
Leuk Lymphoma. 2015, 56(8): 2465-2467.
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Cost-effectiveness analysis of prognostic gene expression signature-based stratification of early breast cancer patients.
Blank, PR, Filipits, M, Dubsky, P, Gutzwiller, F, Lux, MP, Brase, JC, Weber, KE, Rudas, M, Greil, R, Loibl, S, Szucs, TD, Kronenwett, R, Schwenkglenks, M, Gnant, M.
Pharmacoeconomics. 2015, 33(2): 179-190.
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A modified scoring of the NCCN-IPI is more accurate in the elderly and is improved by albumin and ОІ2 -microglobulin.
Melchardt, T, Troppan, K, Weiss, L, Hufnagl, C, Neureiter, D, Tränkenschuh, W, Hopfinger, G, Magnes, T, Deutsch, A, Neumeister, P, Hackl, H, Greil, R, Pichler, M, Egle, A.
Br J Haematol. 2015, 168(2):239-245.
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10th anniversary of the Austrian MDS Platform: aims and ongoing projects.
Burgstaller, S, Bettelheim, P, Krieger, O, Machherndl-Spandl, S, Nösslinger, T, Pleyer, L, Sill, H, Sperr, WR, Stauder, R, Valent, P, Pfeilstöcker, M.
Wien Klin Wochenschr. 2015, 127(1-2): 12-15.
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Lenalidomide and dexamethasone for acute light chain-induced renal failure: a phase II study.
Ludwig, H, Rauch, E, Kuehr, T, Adam, Z, Weissmann, A, Kasparu, H, Autzinger, EM, Heintel, D, Greil, R, Poenisch, W, MГјldГјr, E, Zojer, N.
Haematologica. 2015, 100(3):385-391.
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Prognostic factors for remission of and survival in acquired hemophilia A (AHA): results from the GTH-AH 01/2010 study.
Tiede, A, Klamroth, R, Scharf, RE, Trappe, RU, Holstein, K, Huth-Kühne, A, Gottstein, S, Geisen, U, Schenk, J, Scholz, U, Schilling, K, Neumeister, P, Miesbach, W, Manner, D, Greil, R, von Auer, C, Krause, M, Leimkühler, K, Kalus, U, Blumtritt, J, Werwitzke, S, Budde, E, Koch, A, Knöbl, P.
Blood. 2015, 125(7): 1091-1097.
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Longitudinal analysis of 2293 NSCLC patients: a comprehensive study from the TYROL registry.
Kocher, F, Hilbe, W, Seeber, A, Pircher, A, Schmid, T, Greil, R, Auberger, J, Nevinny-Stickel, M, Sterlacci, W, Tzankov, A, Jamnig, H, Kohler, K, Zabernigg, A, Frotscher, J, Oberaigner, W, Fiegl, M.
LUNG CANCER. 2015, 87(2): 193-200.
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Primary antifungal prophylaxis with micafungin in patients with haematological malignancies: real-life data from a retrospective single-centre observational study.
Nachbaur, D, Angelova, O, Orth-Holler, D, Ditlbacher, A, Lackner, M, Auberger, J, Lass-Florl, C.
EUR J HAEMATOL. 2015, 94(3): 258-264.
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Azacitidine frontline therapy for unfit acute myeloid leukemia patients: Clinical use and outcome prediction.
Ramos, F, ThГ©pot, S, Pleyer, L, Maurillo, L, Itzykson, R, Bargay, J, Stauder, R, Venditti, A, Seegers, V, MartГnez-Robles, V, Burgstaller, S, RГ©cher, C, DebГ©n, G, Gaidano, G, Gardin, C, Musto, P, Greil, R, SГЎnchez-Guijo, F, Fenaux, P.
Leuk Res. 2015, 39(3): 296-306.
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Non-pegylated liposomal doxorubicin in lymphoma: patterns of toxicity and outcome in a large observational trial.
Wasle, I, Gamerith, G, Kocher, F, Mondello, P, Jaeger, T, Walder, A, Auberger, J, Melchardt, T, Linkesch, W, Fiegl, M, Mian, M.
Ann Hematol. 2015, 94(4): 593-601.
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Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy.
Sochalska, M, Tuzlak, S, Egle, A, Villunger, A.
FEBS J. 2015, 282(5): 834-849.
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CD4+ T cells, but not non-classical monocytes, are dispensable for the development of chronic lymphocytic leukemia in the TCL1-tg murine model.
Kocher, T, Asslaber, D, Zaborsky, N, Flenady, S, Denk, U, Reinthaler, P, Ablinger, M, Geisberger, R, Bauer, JW, Seiffert, M, Hartmann, TN, Greil, R, Egle, A, Hofbauer, JP.
Leukemia. 2015, xx.
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AID/APOBEC deaminases and cancer.
Rebhandl, S, Huemer, M, Greil, R, Geisberger, R.
Oncoscience. 2015, 2(4): 320-333.
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Renaissance eines alten Bekannten - Bedeutung des Androgenrezeptors beim Mammakarzinom.
Rinnerthaler, G.
Wiener klinisches Magazin. 2015, 18(6).
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Treatment of Patients With Myelodysplastic Syndrome With Lenalidomide in Clinical Routine in Austria.
Aschauer, G, Greil, R, Linkesch, W, Nösslinger, T, Stauder, R, Burgstaller, S, Fiegl, M, Fridrik, M, Girschikofsky, M, Keil, F, Petzer, A.
Clin Lymphoma Myeloma Leuk. 2015, 15(11): e143-e149.
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Factors Associated with Low-Level Viraemia and Virological Failure: Results from the Austrian HIV Cohort Study.
Leierer, G, Grabmeier-Pfistershammer, K, Steuer, A, Geit, M, Sarcletti, M, Haas, B, Kanatschnig, M, Rappold, M, Zangerle, R, Ledergerber, B, Taylor, N.
PLOS ONE. 2015, 10(11).
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The significance of pretreatment anemia in the era of R-IPI and NCCN-IPI prognostic risk assessment tools: a dual-center study in diffuse large B-cell lymphoma patients.
Troppan, KT, Melchardt, T, Deutsch, A, Schlick, K, Stojakovic, T, Bullock, MD, Reitz, D, Beham-Schmid, C, Weiss, L, Neureiter, D, Wenzl, K, Greil, R, Neumeister, P, Egle, A, Pichler, M.
Eur J Haematol. 2015, 95(6): 538-544.
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The Role of CD44 in the Pathophysiology of Chronic Lymphocytic Leukemia.
Gutjahr, JC, Greil, R, Hartmann, TN.
FRONT IMMUNOL. 2015, 6: 177.
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The genomic expression test EndoPredict is a prognostic tool for identifying risk of local recurrence in postmenopausal endocrine receptor-positive, her2neu-negative breast cancer patients randomised within the prospective ABCSG 8 trial.
Fitzal, F, Filipits, M, Rudas, M, Greil, R, Dietze, O, Samonigg, H, Lax, S, Herz, W, Dubsky, P, Bartsch, R, Kronenwett, R, Gnant, M.
Br J Cancer. 2015, 112(8): 1405-1410.
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Bortezomib, thalidomide and dexamethasone, with or without cyclophosphamide, for patients with previously untreated multiple myeloma: 5-year follow-up.
Ludwig, H, Greil, R, Masszi, T, Spicka, I, Shpilberg, O, Hajek, R, Dmoszynska, A, Paiva, B, Vidriales, MB, Esteves, G, Stoppa, AM, Robinson, D, Chaturvedi, S, Ataman, O, Enny, C, Feng, H, van de Velde, H, Viterbo, L.
Br J Haematol. 2015, 171(3): 3-54.
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Rituximab maintenance for patients with aggressive B-cell lymphoma in first remission: results of the randomized NHL13 trial.
Jaeger, U, Trneny, M, Melzer, H, Praxmarer, M, Nawarawong, W, Ben Yehuda, D, Goldstein, D, Mihaljevic, B, Ilhan, O, Ballova, V, Hedenus, M, Hsiao, LT, Au, WY, Burgstaller, S, Weidinger, G, Keil, F, Dittrich, C, Skrabs, C, Klingler, A, Chott, A, Fridrik, MA, Greil, R.
Haematologica. 2015, 100(7): 955-963.
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How does lenalidomide target the chronic lymphocytic leukemia microenvironment?
Kater, AP, Tonino, SH, Egle, A, Ramsay, AG,
Blood. 2014 Oct 2,124(14):2184-9. doi: 10.1182/blood-2014-05-578286. Epub 2014 Aug 26.
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Old and new news in CLL: "It"s the pathway, stupid!".
Egle, A,
Blood. 2014 Aug 14,124(7):989-90. doi: 10.1182/blood-2014-05-574145.
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CLL cells under flow.
Hartmann TN
Blood. 2014 Jun 5,123(23):3533-4. doi: 10.1182/blood-2014-04-565358. Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia. [Blood. 2014]
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UPDATED REPORT OF THE AUSTRIAN CML REGISTRY
Schmidt, S, Sill, H, Greil, R, Burgstaller, S, Schlogl, E, Petzer, A
HAEMATOLOGICA. 2014, 99: 341-341.
Bevacizumab (BEV) plus chemotherapy (CT) continued beyond first disease progression (PD) in patients with metastatic colorectal cancer (mCRC) previously treated with BEV-based therapy: Outcomes according to KRAS status and first-line CT backbone in the ML18147 study.
Kubicka, S, Greil, R, Andre, T, Bennouna, J, Sastre, J, Van Cutsem, E, Von Moos, R, Osterlund, PJ, Hegde, P, Sersch, MA, Osborne, S, Hermann, F, Arnold, D
J CLIN ONCOL. 2014, 32(3):
Induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil followed by radiotherapy with cetuximab for locally advanced squamous cell carcinoma of the head and neck
Keil, F, Selzer, E, Berghold, A, Reinisch, S, de Vries, A, Greil, R, Bachtiary, B, Tinchon, C, Anderhuber, W, Burian, M, Kasparek, AK, Elsasser, W, Kainz, H, Riedl, R, Kapp, K, Kopp, M, Kornek, G
ONCOL RES TREAT. 2014, 37: 273-273. Ebenfalls in Pubmed gefunden: Eur J Cancer. 2013 Jan,49(2):352-9. doi: 10.1016/j.ejca.2012.08.004. Epub 2012 Sep 14.
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Updated report of the Austrian CML registry
Schmidt, S, Sill, H, Greil, R, Burgstaller, S, Sliwa, T, Petzer, A, Lang, A, Weltermann, A, Voskova, D, Mitterer, M, Valent, P, Eberhard, N, Walder, A, Geissler, K, Andel, J, Hausler, C, Ludescher, C, Oexle, H, Korger, M, Schnallinger, M, Schreieck, S, Krippl, P, Pober, M, Woell, E, Geissler, D, Rochau, U, Siebert, U, Thaler, J, Gastl, G
ONCOL RES TREAT. 2014, 37: 57-58.
INTERIM RESULTS FROM A PHASE IIA STUDY OF THE ANTI-CXCL12 SPIEGELMER OLAPTESED PEGOL (NOX-A12) IN COMBINATION WITH BORTEZOMIB AND DEXAMETHASONE IN PATIENTS WITH MULTIPLE MYELOMA
Ludwig, H, Weisel, K, Petrucci, MT, Leleu, X, Cafro, AM, Kropff, M, Greil, R, Zojer, N, Dummler, T, Kruschinski, A, Riecke, K, Foa, R, Yakoub-Agha, I, Engelhardt, M
HAEMATOLOGICA. 2014, 99: 115-116.
AN INTERNATIONAL, MULTICENTER, PROSPECTIVE, OBSERVATIONAL STUDY OF NEUTROPENIA IN PATIENTS BEING TREATED WITH LENALIDOMIDE plus DEXAMETHASONE FOR RELAPSED OR RELAPSED/REFRACTORY MULTIPLE MYELOMA (RR-MM)
Leleu, X, Terpos, E, Sanz, RG, Cooney, J, OxxxGorman, P, Minarik, J, Greil, R, Williams, C, Gray, D, Szabo, Z
HAEMATOLOGICA. 2014, 99: 368-368.
A PHASE II STUDY OF RITUXIMAB PLUS LENALIDOMIDE IN PATIENTS WITH EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA OF THE MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT LYMPHOMA)
Raderer, M, Kiesewetter, B, Willenbacher, W, Neumeister, P, Fridrik, M, Greil, R
HAEMATOLOGICA. 2014, 99: 226-226.
Malignant Lymphoblasts in T Cell Acute Lymphoblastic Leukemia Express High Levels of Kv1.3
Groessinger, E, Weiss, L, Chen, MY, Wulff, H, Greil, R, Kerschbaum, H
BIOPHYS J. 2014, 106(2): 551A-551A.
Azacitidine frontline therapy for unfit acute myeloid leukemia patients: Clinical use and outcome prediction.
Ramos, F, ThГ©pot, S, Pleyer, L, Maurillo, L, Itzykson, R, Bargay, J, Stauder, R, Venditti, A, Seegers, V, MartГnez-Robles, V, Burgstaller, S, RГ©cher, C, DebГ©n, G, Gaidano, G, Gardin, C, Musto, P, Greil, R, SГЎnchez-Guijo, F, Fenaux, P,
Leuk Res. 2015 Mar,39(3):296-306. doi: 10.1016/j.leukres.2014.12.013. Epub 2014 Dec 31.
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Bone-Targeted Therapy in Metastatic Breast Cancer - All Well-Established Knowledge?
Gampenrieder, SP, Rinnerthaler, G, Greil, R
Breast Care (Basel). 2014 Oct,9(5):323-30. doi: 10.1159/000368710.
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Bendamustine-bortezomib-dexamethasone is an active and well-tolerated regimen in patients with relapsed or refractory multiple myeloma.
Ludwig H, Kasparu H, Leitgeb C, Rauch E, Linkesch W, Zojer N, Greil R, Seebacher A, Pour L, WeiГџmann A, Adam Z.
Blood. 2014 Feb 13,123(7):985-91. doi: 10.1182/blood-2013-08-521468. Epub 2013 Nov 13.
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Overcoming resistance against HER2-targeting agents in fifth-line therapy: is there still a place for bevacizumab in HER2+ breast cancer?
Huemer F, Gampenrieder SP, Schlattau A, Greil R.
Clin Breast Cancer. 2014 Feb,14(1):e17-20. doi: 10.1016/j.clbc.2013.09.009. Epub 2013 Sep 28.
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Female gender may predict response to FOLFIRINOX in patients with unresectable pancreatic cancer: a single institution retrospective review.
Hohla F, Hopfinger G, Romeder F, Rinnerthaler G, Bezan A, Stättner S, Hauser-Kronberger C, Ulmer H, Greil R.
Int J Oncol. 2014 Jan,44(1):319-26. doi: 10.3892/ijo.2013.2176. Epub 2013 Nov 15.
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Sensitive testing of plasma HIV-1 RNA and Sanger sequencing of cellular HIV-1 DNA for the detection of drug resistance prior to starting first-line antiretroviral therapy with etravirine or efavirenz.
Geretti AM, Conibear T, Hill A, Johnson JA, Tambuyzer L, Thys K, Vingerhoets J, Van Delft Y
J Antimicrob Chemother. 2014 Apr,69(4):1090-7. doi: 10.1093/jac/dkt474. Epub 2013 Nov 27.
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Alemtuzumab in chronic lymphocytic leukemia: final results of a large observational multicenter study in mostly pretreated patients.
Fiegl M, Stauder R, Steurer M, Mian M, Hopfinger G, Brychtova Y, Skrabs C, Zabernigg A, Schmid F, Haslbaur F, Winder G, Walder A, Lang A, Voskova D, Greil R, Mayer J, Gastl G
Ann Hematol. 2014 Feb,93(2):267-77. doi: 10.1007/s00277-013-1966-z. Epub 2013 Nov 30.
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Differential survival trends of stage II colorectal cancer patients relate to promoter methylation status of PCDH10, SPARC and UCHL1.
Heitzer E, Artl M, Filipits M, Resel M, Graf R, Weißenbacher B, Lax S, Gnant M, Wrba F, Greil R, Dietze O, Hofbauer F, Böhm G, Höfler G, Samonigg H, Schaberl-Moser R, Balic M, Dandachi N.
Mod Pathol. 2014 Jun,27(6):906-15. doi: 10.1038/modpathol.2013.204. Epub 2013 Dec 6.
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Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind phase 3 trial.
Butts C, Socinski MA, Mitchell PL, Thatcher N, Havel L, Krzakowski M, Nawrocki S, Ciuleanu TE, Bosquée L, Trigo JM, Spira A, Tremblay L, Nyman J, Ramlau R, Wickart-Johansson G, Ellis P, Gladkov O, Pereira JR, Eberhardt WE, Helwig C, Schröder A, Shepherd FA
Lancet Oncol. 2014 Jan,15(1):59-68. doi: 10.1016/S1470-2045(13)70510-2. Epub 2013 Dec 9.
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Predicting distant recurrence in receptor-positive breast cancer patients with limited clinicopathological risk: using the PAM50 Risk of Recurrence score in 1478 postmenopausal patients of the ABCSG-8 trial treated with adjuvant endocrine therapy alone.
Gnant M, Filipits M, Greil R, Stoeger H, Rudas M, Bago-Horvath Z, Mlineritsch B, Kwasny W, Knauer M, Singer C, Jakesz R, Dubsky P, Fitzal F, Bartsch R, Steger G, Balic M, Ressler S, Cowens JW, Storhoff J, Ferree S, Schaper C, Liu S, et al.
Ann Oncol. 2014 Feb,25(2):339-45. doi: 10.1093/annonc/mdt494. Epub 2013 Dec 16.
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Hypertension as a predictive marker for bevacizumab in metastatic breast cancer: results from a retrospective matched-pair analysis.
Gampenrieder SP, Romeder F, MuГџ C, Pircher M, Ressler S, Rinnerthaler G, Bartsch R, Sattlberger C, Mlineritsch B, Greil R.
Anticancer Res. 2014 Jan,34(1):227-33.
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Performance characteristics of the COBAS Ampliprep/COBAS TaqMan v2.0 and the Abbott RealTime hepatitis C assays - implications for response-guided therapy in genotype 1 infections.
Taylor N, Haschke-Becher E, Greil R, Strasser M, Oberkofler H.
Antivir Ther. 2014,19(5):449-54. doi: 10.3851/IMP2723. Epub 2014 Jan 16.
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Impact of mutational status on outcomes in myelofibrosis patients treated with ruxolitinib in the COMFORT-II study.
Guglielmelli P, Biamonte F, Rotunno G, Artusi V, Artuso L, Bernardis I, Tenedini E, Pieri L, Paoli C, Mannarelli C, Fjerza R, Rumi E, Stalbovskaya V, Squires M, Cazzola M, Manfredini R, Harrison C, Tagliafico E, Vannucchi AM
Blood. 2014 Apr 3,123(14):2157-60. doi: 10.1182/blood-2013-11-536557. Epub 2014 Jan 23.
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The PAM50 risk-of-recurrence score predicts risk for late distant recurrence after endocrine therapy in postmenopausal women with endocrine-responsive early breast cancer.
Filipits M, Nielsen TO, Rudas M, Greil R, Stöger H, Jakesz R, Bago-Horvath Z, Dietze O, Regitnig P, Gruber-Rossipal C, Müller-Holzner E, Singer CF, Mlineritsch B, Dubsky P, Bauernhofer T, Hubalek M, Knauer M, Trapl H, Fesl C, Schaper C, Ferree S, Liu S, et al.
Clin Cancer Res. 2014 Mar 1,20(5):1298-305. doi: 10.1158/1078-0432.CCR-13-1845. Epub 2014 Feb 11.
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Azacitidine in CMML: matched-pair analyses of daily-life patients reveal modest effects on clinical course and survival.
Pleyer L, Germing U, Sperr WR, Linkesch W, Burgstaller S, Stauder R, Girschikofsky M, Schreder M, Pfeilstocker M, Lang A, Sliwa T, Geissler D, Schlick K, Placher-Sorko G, Theiler G, Thaler J, Mitrovic M, Neureiter D, Valent P, Greil R.
Leuk Res. 2014 Apr,38(4):475-83. doi: 10.1016/j.leukres.2014.01.006. Epub 2014 Jan 18.
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Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials.
EBCTCG (Early Breast Cancer Trialists' Collaborative Group), McGale P, Taylor C, Correa C, Cutter D, Duane F, Ewertz M, Gray R, Mannu G, Peto R, Whelan T, Wang Y, Wang Z, Darby S.
Lancet. 2014 Jun 21,383(9935):2127-35. doi: 10.1016/S0140-6736(14)60488-8. Epub 2014 Mar 19.
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Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.
Tassara M, Döhner K, Brossart P, Held G, Götze K, Horst HA, Ringhoffer M, Köhne CH, Kremers S, Raghavachar A, Wulf G, Kirchen H, Nachbaur D, Derigs HG, Wattad M, Koller E, Brugger W, Matzdorff A, Greil R, Heil G, Paschka P, Gaidzik VI, et al.
Blood. 2014 Jun 26,123(26):4027-36. doi: 10.1182/blood-2013-12-546283. Epub 2014 May 5.
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Targeted therapy in advanced metastatic colorectal cancer: current concepts and perspectives.
Hohla F, Winder T, Greil R, Rick FG, Block NL, Schally AV.
World J Gastroenterol. 2014 May 28,20(20):6102-12. doi: 10.3748/wjg.v20.i20.6102.
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Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia.
Byrd JC, Brown JR, O'Brien S, Barrientos JC, Kay NE, Reddy NM, Coutre S, Tam CS, Mulligan SP, Jaeger U, Devereux S, Barr PM, Furman RR, Kipps TJ, Cymbalista F, Pocock C, Thornton P, Caligaris-Cappio F, Robak T, Delgado J, Schuster SJ, Montillo M, et al.
N Engl J Med. 2014 Jul 17,371(3):213-23. doi: 10.1056/NEJMoa1400376. Epub 2014 May 31.
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Oxaliplatin, fluorouracil and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label randomised phase 3 trial.
Taieb J, Tabernero J, Mini E, Subtil F, Folprecht G, Van Laethem JL, Thaler J, Bridgewater J, Petersen LN, Blons H, Collette L, Van Cutsem E, Rougier P, Salazar R, Bedenne L, Emile JF, Laurent-Puig P, Lepage C
Lancet Oncol. 2014 Jul,15(8):862-73. doi: 10.1016/S1470-2045(14)70227-X. Epub 2014 Jun 11.
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Azacitidine in 302 patients with WHO-defined acute myeloid leukemia: results from the Austrian Azacitidine Registry of the AGMT-Study Group.
Pleyer L, Burgstaller S, Girschikofsky M, Linkesch W, Stauder R, Pfeilstocker M, Schreder M, Tinchon C, Sliwa T, Lang A, Sperr WR, Krippl P, Geissler D, Voskova D, Schlick K, Thaler J, Machherndl-Spandl S, Theiler G, EckmГјllner O, Greil R.
Ann Hematol. 2014 Nov,93(11):1825-38. doi: 10.1007/s00277-014-2126-9. Epub 2014 Jun 21.
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Assessment of TP53 functionality in chronic lymphocytic leukaemia by different assays, an ERIC-wide approach.
Te Raa GD, MalДЌikovГЎ J, Mraz M, Trbusek M, Le Garff-Tavernier M, Merle-BГ©ral H, Greil R, Merkel O, PospГЕЎilovГЎ S, Lin K, Pettitt AR, Stankovic T, van Oers MH, Eldering E, Stilgenbauer S, Zenz T, Kater AP
Br J Haematol. 2014 Nov,167(4):565-9. doi: 10.1111/bjh.13006. Epub 2014 Jun 30.
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Multicenter phase II study evaluating docetaxel and cisplatin as neoadjuvant induction regimen prior to surgery or radiochemotherapy with docetaxel, followed by adjuvant docetaxel therapy in chemonaive patients with NSCLC stage II IIIA and IIIB (TAX-AT 1.203 Trial).
Kocher F, Pircher A, Mohn-Staudner A, Romeder F, Duller W, Steinmaurer M, Eckmayr J, Schmid T, Hilbe W, Fiegl M, Greil R.
Lung Cancer. 2014 Sep,85(3):395-400. doi: 10.1016/j.lungcan.2014.06.019. Epub 2014 Jul 3.
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A patient diagnosed with BRAF-mutated non-small cell lung cancer and hairy cell leukemia: at last, which entity is really carrying the BRAF mutation?
Schlick K, Troch M, Placher-Sorko G, Faber V, Neureiter D, Berghoff AS, Preusser M, Greil R, Hopfinger G.
Ann Hematol. 2015 Feb,94(2):345-6. doi: 10.1007/s00277-014-2162-5. Epub 2014 Jul 24.
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MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis.
Benner A, Mansouri L, Rossi D, Majid A, Willander K, Parker A, Bond G, Pavlova S, Nückel H, Merkel O, Ghia P, Montserrat E, Kaderi MA, Rosenquist R, Gaidano G, Dyer MJ, Söderkvist P, Linderholm M, Oscier D, Tvaruzkova Z, Pospisilova S, Dührsen U, Greil R, Döhner H, Stilgenbauer S, Zenz T, European Research Initiative on CLL (ERIC)
Haematologica. 2014 Aug,99(8):1285-91. doi: 10.3324/haematol.2013.101170.
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A randomized, open-label multicentre phase 2/3 study to evaluate the safety and efficacy of lumiliximab in combination with fludarabine cyclophosphamide and rituximab versus fludarabine cyclophosphamide and rituximab versus fludarabine cyclophosphamide and rituximab alone in subjects with relapsed chronic lymphocytic leukaemia.
Awan FT, Hillmen P, Hellmann A, Robak T, Hughes SG, Trone D, Shannon M, Flinn IW, Byrd JC
Br J Haematol. 2014 Nov,167(4):466-77. doi: 10.1111/bjh.13061. Epub 2014 Aug 8.
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Lenalidomide and dexamethasone in transplant-ineligible patients with myeloma.
Benboubker L, Dimopoulos MA, Dispenzieri A, Catalano J, Belch AR, Cavo M, Pinto A, Weisel K, Ludwig H, Bahlis N, Banos A, Tiab M, Delforge M, Cavenagh J, Geraldes C, Lee JJ, Chen C, Oriol A, de la Rubia J, Qiu L, White DJ, Binder D, et al.
N Engl J Med. 2014 Sep 4,371(10):906-17. doi: 10.1056/NEJMoa1402551.
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Selecting first-line bevacizumab-containing therapy for advanced breast cancer: TURANDOT risk factor analyses.
Brodowicz T, Lang I, Kahan Z, Greil R, Beslija S, Stemmer SM, Kaufman B, Petruzelka L, Eniu A, Anghel R, Koynov K, Vrbanec D, Pienkowski T, Melichar B, Spanik S, Ahlers S, Messinger D, Inbar MJ, Zielinski C.
Br J Cancer. 2014 Nov 25,111(11):2051-7. doi: 10.1038/bjc.2014.504. Epub 2014 Sep 30.
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Preoperative Treatment with Capecitabine, Cetuximab and Radiotherapy for Primary Locally Advanced Rectal Cancer - A Phase II Clinical Trial.
Eisterer W, DE Vries A, Ofner D, Rabl H, Koplmüller R, Greil R, Tschmelitsch J, Schmid R, Kapp K, Lukas P, Sedlmayer F, Höfler G, Gnant M, Thaler J
Anticancer Res. 2014 Nov,34(11):6767-73.
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Lenalidomide and dexamethasone for acute light chain-induced renal failure: a phase II study.
Ludwig H, Rauch E, Kuehr T, Adam Z, Weissmann A, Kasparu H, Autzinger EM, Heintel D, Greil R, Poenisch W, MГјldГјr E, Zojer N.
Haematologica. 2015 Mar,100(3):385-91. doi: 10.3324/haematol.2014.115204. Epub 2014 Nov 14.
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Cost-Effectiveness Analysis of Prognostic Gene Expression Signature-Based Stratification of Early Breast Cancer Patients.
Blank PR, Filipits M, Dubsky P, Gutzwiller F, Lux MP, Brase JC, Weber KE, Rudas M, Greil R, Loibl S, Szucs TD, Kronenwett R, Schwenkglenks M, Gnant M.
Pharmacoeconomics. 2015 Feb,33(2):179-90. doi: 10.1007/s40273-014-0227-x.
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Prognostic factors for remission of and survival in acquired hemophilia A (AHA): results from the GTH-AH 01/2010 study.
Tiede A, Klamroth R, Scharf RE, Trappe RU, Holstein K, Huth-Kühne A, Gottstein S, Geisen U, Schenk J, Scholz U, Schilling K, Neumeister P, Miesbach W, Manner D, Greil R,von Auer C, Krause M, Leimkühler K, Kalus U, Blumtritt J, Werwitzke S, Budde E, Koch A, Knöbl P.
Blood. 2015 Feb 12,125(7):1091-7. doi: 10.1182/blood-2014-07-587089. Epub 2014 Dec 18.
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A phase 1 dose escalation study of BI 831266, an inhibitor of Aurora kinase B, in patients with advanced solid tumors.
Dittrich C, Fridrik MA, Koenigsberg R, Lee C, Goeldner R, Hilbert J, Greil R.
Invest New Drugs. 2015 Apr,33(2):409-22. doi: 10.1007/s10637-014-0201-7. Epub 2014 Dec 23.
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Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer K, Goergen H, Hitz F, Zijlstra JM, Greil R, Markova J, Sasse S, Fuchs M, Topp MS, Soekler M, Mathas S, Meissner J, Wilhelm M, Koch P, Lindemann H, Schalk E, Semrau R, Kriz J, Vieler T, Bentz M, Lange E, Mahlberg R, Hassler A, Vogelhuber M, Hahn D, Mezger J, Krause SW, Skoetz N, Böll B, von Tresckow B, Diehl V, Hallek M, Borchmann P, Stein H, Eich H, Engert A, on behalf of the German Hodgkin Study Group, the Swiss Group for Clinical Cancer Research, the Österreichische Arbeitsgemeinschaft für Klinische Pharmakologie und Therapie.
Lancet. 2015 Apr 11,385(9976):1418-27. doi: 10.1016/S0140-6736(14)61469-0. Epub 2014 Dec 22.
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Pleural decortication of a marginal zone lymphoma.
Melchardt T, Weiss L, Namberger K, Pretsch I, Hutter J, Rettenbacher L, Neureiter D, Troch M, Greil R, Egle A.
Ann Hematol. 2014 Jul,93(7):1253-4. doi: 10.1007/s00277-013-1960-5. Epub 2013 Nov 22.
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Increased body mass index is associated with improved overall survival in diffuse large B-cell lymphoma.
Weiss L, Melchardt T, Habringer S, Boekstegers A, Hufnagl C, Neureiter D, Hopfinger G, Greil R, Egle A.
Ann Oncol. 2014 Jan,25(1):171-6. doi: 10.1093/annonc/mdt481. Epub 2013 Dec 3.
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Lenalidomide in combination with vorinostat and dexamethasone for the treatment of relapsed/refractory peripheral T cell lymphoma (PTCL): report of a phase I/II trial.
Hopfinger G, Nösslinger T, Lang A, Linkesch W, Melchardt T, Weiss L, Egle A, Greil R.
Ann Hematol. 2014 Mar,93(3):459-62. doi: 10.1007/s00277-014-2009-0. Epub 2014 Jan 18.
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Human immunodeficiency virus type 2 infections in Austria.
Taylor N, Kern JM, Prammer W, Lang A, Haas B, Gisinger M, Zangerle R, Egle A, Greil R, Oberkofler H, Eberle J.
Wien Klin Wochenschr. 2014 Apr,126(7-8):212-6. doi: 10.1007/s00508-013-0493-1. Epub 2014 Jan 18.
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Liver toxicity during temozolomide chemotherapy caused by Chinese herbs.
Melchardt T, Magnes T, Weiss L, Grundbichler M, Strasser M, Hufnagl C, Moik M, Greil R, Egle A.
BMC Complement Altern Med. 2014 Mar 30,14:115. doi: 10.1186/1472-6882-14-115.
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Treatment of aggressive B-cell lymphoma in elderly patients: influence of single nucleotide polymorphisms affecting pharmacodynamics of chemotherapeutics.
Melchardt T, Weiss L, Hufnagl C, Neureiter D, Kemmerling R, Morre P, Boekstegers A, Hopfinger G, Auberger J, Steinkirchner S, Pleyer L, Greil R, Egle A.
Leuk Lymphoma. 2015 Feb,56(2):353-60. doi: 10.3109/10428194.2014.916798. Epub 2014 Jun 25.
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C-reactive protein level is a prognostic indicator for survival and improves the predictive ability of the R-IPI score in diffuse large B-cell lymphoma patients.
Troppan KT, Schlick K, Deutsch A, Melchardt T, Egle A, Stojakovic T, Beham-Schmid C, Weiss L, Neureiter D, Wenzl K, Greil R, Neumeister P, Pichler M.
Br J Cancer. 2014 Jul 8,111(1):55-60. doi: 10.1038/bjc.2014.277. Epub 2014 May 29.
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Kasabach-Merritt phenomenon in hepatic angiosarcoma.
Habringer S, Boekstegers A, Weiss L, Hopfinger G, Meissnitzer T, Melchardt T, Egle A, Greil R.
Br J Haematol. 2014 Dec,167(5):716-8. doi: 10.1111/bjh.13049. Epub 2014 Jul 24.
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A modified scoring of the NCCN-IPI is more accurate in the elderly and is improved by albumin and ГЋВІ(2) -microglobulin.
Melchardt T, Troppan K, Weiss L, Hufnagl C, Neureiter D, Tränkenschuh W, Hopfinger G, Magnes T, Deutsch A, Neumeister P, Hackl H, Greil R, Pichler M, Egle A.
Br J Haematol. 2015 Jan,168(2):239-45. doi: 10.1111/bjh.13116. Epub 2014 Sep 19.
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Molecular responses and chromosomal aberrations in patients with polycythemia vera treated with peg-proline-interferon alpha-2b.
Them NC, Bagienski K, Berg T, Gisslinger B, Schalling M, Chen D, Buxhofer-Ausch V, Thaler J, Schloegl E, Gastl GA, Wolf D, Strecker K, Egle A, Melchardt T, Burgstaller S, Willenbacher E, Zagrijtschuk O, Klade C, Greil R, Gisslinger H, Kralovics R.
Am J Hematol. 2015 Apr,90(4):288-94. doi: 10.1002/ajh.23928. Epub 2015 Mar 2.
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The pathogenic relevance of the prognostic markers CD38 and CD49d in chronic lymphocytic leukemia.
Brachtl G, PiГ±Гіn Hofbauer J, Greil R, Hartmann TN.
Ann Hematol. 2014 Mar,93(3):361-74. doi: 10.1007/s00277-013-1967-y. Epub 2013 Nov 28.
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Epirubicin and docetaxel with or without capecitabine as neoadjuvant treatment for early breast cancer: final results of a randomized phase III study (ABCSG-24).
Steger GG, Greil R, Lang A, Rudas M, Fitzal F, Mlineritsch B, Hartmann BL, Bartsch R, Melbinger E, Hubalek M, Stoeger H, Dubsky P, Ressler S, Petzer AL, Singer CF, Muss C, Jakesz R, Gampenrieder SP, Zielinski CC, Fesl C, Gnant M
Ann Oncol. 2014 Feb,25(2):366-71. doi: 10.1093/annonc/mdt508. Epub 2013 Dec 16.
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Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility of chronic lymphocytic leukemia cells.
Hofbauer SW, Krenn PW, Ganghammer S, Asslaber D, Pichler U, Oberascher K, Henschler R, Wallner M, Kerschbaum H, Greil R, Hartmann TN.
Blood. 2014 Apr 3,123(14):2181-8. doi: 10.1182/blood-2013-08-523563. Epub 2014 Feb 5.
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The CXCR4 and adhesion molecule expression of CD34+ hematopoietic cells mobilized by on-demand" addition of plerixafor to granulocyte-colony-stimulating factor."
Girbl T, Lunzer V, Greil R, Namberger K, Hartmann TN.
Transfusion. 2014 Sep,54(9):2325-35. doi: 10.1111/trf.12632. Epub 2014 Mar 28.
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CD18 (ITGB2) expression in chronic lymphocytic leukaemia is regulated by DNA methylation-dependent and -independent mechanisms.
Hutterer E, Asslaber D, Caldana C, Krenn PW, Zucchetto A, Gattei V, Greil R, Hartmann TN.
Br J Haematol. 2015 Apr,169(2):286-9. doi: 10.1111/bjh.13188. Epub 2014 Oct 17.
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Zoledronic acid combined with adjuvant endocrine therapy of tamoxifen versus anastrozol plus ovarian function suppression in premenopausal early breast cancer: final analysis of the Austrian Breast and Colorectal Cancer Study Group Trial 12.
Gnant, M, Mlineritsch, B, Stoeger, H, Luschin-Ebengreuth, G, Knauer, M, Moik, M, Jakesz, R, Seifert, M, Taucher, S, Bjelic-Radisic, V, Balic, M, Eidtmann, H, Eiermann, W, Steger, G, Kwasny, W, Dubsky, P, Selim, U, Fitzal, F, Hochreiner, G, Wette, V, Sevelda, P, Ploner, F, Bartsch, R, Fesl, C, Greil, R
Ann Oncol. 2015 Feb,26(2):313-20. doi: 10.1093/annonc/mdu544
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VLA-4 and CXCR4 overexpression in bone marrow of an aleukemic B-cell acute lymphoblastic leukemia presenting with osteolytic bone lesions.
Hinterseer E, Stiefel O, Neureiter D, Kandler G, Vogt S, Hutter J, Strasser G, Greil R, Hartmann TN, Hopfinger G.
Leuk Lymphoma. 2015 Feb 9:1-3. [Epub ahead of print]
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Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade.
Grössinger EM, Weiss L, Zierler S, Rebhandl S, Krenn PW, Hinterseer E, Schmölzer J, Asslaber D, Hainzl S, Neureiter D, Egle A, Piñón-Hofbauer J, Hartmann TN, Greil R, Kerschbaum HH.
Leukemia. 2014 Apr,28(4):954-8. doi: 10.1038/leu.2014.37. Epub 2014 Jan 20.
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Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia.
Rebhandl S, Huemer M, Zaborsky N, Gassner FJ, Catakovic K, Felder TK, Greil R, Geisberger R.
Eur J Immunol. 2014 Jul,44(7):2175-87. doi: 10.1002/eji.201343853. Epub 2014 Apr 15.
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APOBEC3 signature mutations in chronic lymphocytic leukemia.
Rebhandl S, Huemer M, Gassner FJ, Zaborsky N, Hebenstreit D, Catakovic K, Grössinger EM, Greil R, Geisberger R.
Leukemia. 2014 Sep,28(9):1929-32. doi: 10.1038/leu.2014.160. Epub 2014 May 20.
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AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.
Huemer M, Rebhandl S, Zaborsky N, Gassner FJ, Hainzl S, Weiss L, Hebenstreit D, Greil R, Geisberger R.
Eur J Immunol. 2014 Dec,44(12):3747-57. doi: 10.1002/eji.201344421. Epub 2014 Oct 18.
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Chemotherapy-induced augmentation of T cells expressing inhibitory receptors is reversed by treatment with lenalidomide in chronic lymphocytic leukemia.
Gassner FJ, Zaborsky N, Neureiter D, Huemer M, Melchardt T, Egle A, Rebhandl S, Catakovic K, Hartmann TN, Greil R, Geisberger R.
Haematologica. 2014 May,99(5):67-9. doi: 10.3324/haematol.2013.098459. Epub 2014 Feb 21.
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Protein Kinase C-?-Dependent Activation of NF-?B in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B Cells In Vivo.
Lutzny G, Kocher T, Schmidt-Supprian M, Rudelius M, Klein-Hitpass L, Finch AJ, Dürig J, Wagner M, Haferlach C, Kohlmann A, Schnittger S, Seifert M, Wanninger S, Zaborsky N, Oostendorp R, Ruland J, Leitges M, Kuhnt T, Schäfer Y, Lampl B, Peschel C, Egle A, Ringshausen I.
Cancer Cell. 2013 Jan 14,23(1):77-92. doi: 10.1016/j.ccr.2012.12.003.
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p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa.
Valente LJ, Gray DH, Michalak EM, Pinon-Hofbauer J, Egle A, Scott CL, Janic A, Strasser A.
Cell Rep. 2013 May 30,3(5):1339-45. doi: 10.1016/j.celrep.2013.04.012. Epub 2013 May 9.
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Bid-ding for mercy: twisted killer in action.
Egle A, Asslaber D, Villunger A, Pinon-Hofbauer J.
Cell Death and Differentiation. 2013 Jul,20(7):847-9. doi: 10.1038/cdd.2013.40.
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[Autoimmune hemolysis accompanied by thrombopenia: consumption or myelodysplasia?].
Melchardt, T, Weiss, L, Egle, A,
Dtsch Med Wochenschr. 2013 Oct,138(41):2093-5. doi: 10.1055/s-0033-1349586. Epub 2013 Oct 1.
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CD49d is overexpressed by trisomy 12 chronic lymphocytic leukemia cells: evidence for a methylation-dependent regulation mechanism.
Zucchetto A, Caldana C, Benedetti D, Tissino E, Rossi FM, Hutterer E, Pozzo F, Bomben R, Dal Bo M, D'Arena G, Zaja F, Pozzato G, Di Raimondo F, Hartmann TN, Rossi D, Gaidano G, Del Poeta G, Gattei V.
Blood. 2013 Nov 7,122(19):3317-21. doi: 10.1182/blood-2013-06-507335. Epub 2013 Sep 25.
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MESENCHYMAL STEM CELLS RETAIN THEIR PRO-OLIGODENDROGENIC ACTIVITY DURING AGING: A RATIONALE FOR AUTOLOGOUS TRANSPLANTATION IN MULTIPLE SCLEROSIS
Rivera, FJ, Wodnar, R, Feichtner, M, Oberbauer, E, Brachtl, G, Greil, R, Rohde, E, Franklin, RJM, Aigner, L
GLIA. 2013, 61: S52-S52.
Updated report of the Austrian CML registry
Schmidt, S, Burgstaller, S, Linkesch, W, Greil, R, Schlogl, E, Fridrik, M, Krieger, O, Petzer, A, Lang, A, Mitterer, M, Valent, P, Walder, A, Sliwa, T, Keil, F, Korger, M, Hausler, C, Woll, E, Oexle, H, Schnallinger, M, Pober, M, Rochau, U, Siebert, U, Thaler, J, Gastl, G
ONKOLOGIE. 2013, 36: 63-63.
Lapatinib plus Caelyx in patients with advanced or metastatic Her 2 positive breast cancer following failure of Trastuzumab therapy - A Phase II study of the Arbeitsgemeinschaft Medikamentose Tumortherapie
Pircher, M, Mlineritsch, B, Fridrik, M, Dittrich, C, Lang, A, Petru, E, Weltermann, A, Thaler, J, Hufnagl, C, Gampenrieder, SP, Ressler, S, Rinnerthaler, G, Ulmer, H, Greil, R
ONKOLOGIE. 2013, 36: 159-159.
"ABCSG C-07 EXERCISE - Pilot study": Endurance exercise to reduce the recurrence rate after adjuvant chemotherapy for colorectal cancer
Piringer, G, Fridrik, M, Fridrik, A, Zabernigg, A, Greil, R, Eisterer, W, Tschmelitsch, J, Lang, A, Gnant, M, Thaler, J
ONKOLOGIE. 2013, 36: 72-72.
Hypertension as a predictive marker for bevacizumab in metastatic breast cancer: updated results from a retrospective matched-pair analysis
Gampenrieder, SP, Romeder, F, Muss, C, Pircher, M, Ressler, S, Rinnerthaler, G, Bartsch, R, Sattlberger, C, Mlineritsch, B, Greil, R
Anticancer Res. 2014 Jan,34(1):227-33.
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Two patients diagnosed with coexisting hematologic and oncologic BRAF V600E mutated malignancies. Which entity is really carrying the BRAF (V600E) mutation?
Schlick, K, Troch, M, Placher-Sorko, G, Faber, V, Neureiter, D, Greil, R, Hopfinger, G
ONKOLOGIE. 2013, 36: 168-169.
Aktuelle Diagnostik und Therapieoptionen bei aggressiven Lymphomen.
Hopfinger, G, Greil, R
Bremen, London, Boston: UniMed Verlag, 2013. (ISBN: 978-3-8374-1407-3)
Systemische Therapie des prämenopausalen Mammakarzinoms
Ressler Sigrun, Greil Richard
Die Punkte. 2013.
ASH 2012 update chronic lymphocytic leukemia—the best is yet to come
Weiss, L, Melchardt, T, Greil, R, Hopfinger, G,
Magazine of European Medical Oncology. 2013, Volume 6, Issue 3: 177-180.
Mycophenolatmofetil und Azathioprin in der Schwangerschaft bei einer Patientin mit systemischem Lupus erythematodes.
Psenak, O, Studnicka-Benke, A, Greil, R
Rheuma plus. 2013, 12: 18-20.
Induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil followed by radiotherapy with cetuximab for locally advanced squamous cell carcinoma of the head and neck.
Keil F, Selzer E, Berghold A, Reinisch S, Kapp KS, De Vries A, Greil R, Bachtiary B, Tinchon C, Anderhuber W, Burian M, Kasparek AK, Elsäßer W, Kainz H, Riedl R, Kopp M, Kornek G.
Eur J Cancer. 2013 Jan,49(2):352-9. doi: 10.1016/j.ejca.2012.08.004. Epub 2012 Sep 14.
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Rituximab plus subcutaneous cladribine in patients with extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue: a phase II study by the Arbeitsgemeinschaft Medikamentose Tumortherapie.
Troch M, Kiesewetter B, Willenbacher W, Willenbacher E, Zebisch A, Linkesch W, Fridrik M, MГјllauer L, Greil R, Raderer M.
Haematologica. 2013 Feb,98(2):264-8. doi: 10.3324/haematol.2012.072587. Epub 2012 Sep 14.
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EndoPredict improves the prognostic classification derived from common clinical guidelines in ER-positive, HER2-negative early breast cancer.
Dubsky P, Filipits M, Jakesz R, Rudas M, Singer CF, Greil R, Dietze O, Luisser I, Klug E, Sedivy R, Bachner M, Mayr D, Schmidt M, Gehrmann MC, Petry C, Weber KE, Kronenwett R, Brase JC, Gnant M
Ann Oncol. 2013 Mar,24(3):640-7. doi: 10.1093/annonc/mds334. Epub 2012 Oct 3.
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Randomized phase II study of bortezomib, thalidomide and dexamethasone with or without cyclophosphamide as induction therapy in previously untreated multiple myeloma.
Ludwig H, Viterbo L, Greil R, Masszi T, Spicka I, Shpilberg O, Hajek R, Dmoszynska A, Paiva B, Vidriales MB, Esteves G, Stoppa AM, Robinson D Jr, Ricci D, Cakana A, Enny C, Feng H, van de Velde H, Harousseau JL.
J Clin Oncol. 2013 Jan 10,31(2):247-55. doi: 10.1200/JCO.2011.39.5137. Epub 2012 Oct 22.
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Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): a randomised phase 3 trial.
Bennouna J, Sastre J, Arnold D, Г–sterlund P, Greil R, Van Cutsem E, von Moos R, ViГ©itez JM, BouchГ© O, Borg C, Steffens CC, Alonso-OrduГ±a V, Schlichting C, Reyes-Rivera I, Bendahmane B, AndrГ© T, Kubicka S
Lancet Oncol. 2013 Jan,14(1):29-37. doi: 10.1016/S1470-2045(12)70477-1. Epub 2012 Nov 16.
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CYP2D6 metabolism and patient outcome in the Austrian Breast and Colorectal Cancer Study Group trial (ABCSG) 8.
Goetz MP, Suman VJ, Hoskin TL, Gnant M, Filipits M, Safgren SL, Kuffel M, Jakesz R, Rudas M, Greil R, Dietze O, Lang A, Offner F, Reynolds CA, Weinshilboum RM, Ames MM, Ingle JN.
Clin Cancer Res. 2013 Jan 15,19(2):500-7. doi: 10.1158/1078-0432.CCR-12-2153. Epub 2012 Dec 4.
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Topical evening primrose oil for reduction of bortezomib-induced skin reactions.
Auberger J, Vogt S, Hopfinger G, Clausen J, Greil R.
Ann Hematol. 2013 Jul,92(7):995-6. doi: 10.1007/s00277-012-1656-2. Epub 2012 Dec 22.
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Utility of PCR in diagnosis of invasive fungal infections: real-life data from a multicenter study.
Lass-Flörl C, Mutschlechner W, Aigner M, Grif K, Marth C, Girschikofsky M, Grander W, Greil R, Russ G, Cerkl P, Eller M, Kropshofer G, Eschertzhuber S, Kathrein H, Schmid S, Beer R, Lorenz I, Theurl I, Nachbaur D.
J Clin Microbiol. 2013 Mar,51(3):863-8. doi: 10.1128/JCM.02965-12. Epub 2012 Dec 26.
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A case of long-term remission with ofatumumab maintenance therapy in multiply relapsed and rituximab-refractory chronic lymphocytic leukaemia with deletion 17p.
Namberger K, Weiss L, Krause B, Melchardt T, Greil R.
Eur J Haematol. 2013 Apr,90(4):349-50. doi: 10.1111/ejh.12065. Epub 2013 Feb 14.
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Bevacizumab plus paclitaxel versus bevacizumab plus capecitabine as first-line treatment for HER2-negative metastatic breast cancer: interim efficacy results of the randomised, open-label non-inferiority phase 3 TURANDOT trial.
Lang I, Brodowicz T, Ryvo L, Kahan Z, Greil R, Beslija S, Stemmer SM, Kaufman B, Zvirbule Z, Steger GG, Melichar B, Pienkowski T, Sirbu D, Messinger D, Zielinski C
Lancet Oncol. 2013 Feb,14(2):125-33. doi: 10.1016/S1470-2045(12)70566-1. Epub 2013 Jan 10.
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ABVD in older patients with early-stage Hodgkin lymphoma treated within the German Hodgkin Study Group HD10 and HD11 trials.
Böll B, Görgen H, Fuchs M, Pluetschow A, Eich HT, Bargetzi MJ, Weidmann E, Junghanß C, Greil R, Scherpe A, Schmalz O, Eichenauer DA, von Tresckow B, Rothe A, Diehl V, Engert A, Borchmann P.
J Clin Oncol. 2013 Apr 20,31(12):1522-9. doi: 10.1200/JCO.2012.45.4181. Epub 2013 Mar 18.
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Efficacy of tamoxifen ± aminoglutethimide in normal weight and overweight postmenopausal patients with hormone receptor-positive breast cancer: an analysis of 1509 patients of the ABCSG-06 trial.
Pfeiler G, Stöger H, Dubsky P, Mlineritsch B, Singer C, Balic M, Fitzal F, Moik M, Kwasny W, Selim U, Renner K, Ploner F, Steger GG, Seifert M, Hofbauer F, Sandbichler P, Samonigg H, Jakesz R, Greil R, Fesl C, Gnant M
Br J Cancer. 2013 Apr 16,108(7):1408-14. doi: 10.1038/bjc.2013.114. Epub 2013 Mar 19.
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AVEREL: a randomized phase III Trial evaluating bevacizumab in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer.
Gianni L, Romieu GH, Lichinitser M, Serrano SV, Mansutti M, Pivot X, Mariani P, Andre F, Chan A, Lipatov O, Chan S, Wardley A, Greil R, Moore N, Prot S, Pallaud C, Semiglazov V.
J Clin Oncol. 2013 May 10,31(14):1719-25. doi: 10.1200/JCO.2012.44.7912. Epub 2013 Apr 8.
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Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG).
Gaidzik VI, Schlenk RF, Paschka P, Stölzle A, Späth D, Kuendgen A, von Lilienfeld-Toal M, Brugger W, Derigs HG, Kremers S, Greil R, Raghavachar A, Ringhoffer M, Salih HR, Wattad M, Kirchen HG, Runde V, Heil G, Petzer AL, Girschikofsky M, Heuser M, Kayser S, et al.
Blood. 2013 Jun 6,121(23):4769-77. doi: 10.1182/blood-2012-10-461624. Epub 2013 Apr 30.
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Randomized phase II study of the anti-epidermal growth factor receptor monoclonal antibody cetuximab with cisplatin versus cisplatin alone in patients with metastatic triple-negative breast cancer.
Baselga J, GГіmez P, Greil R, Braga S, Climent MA, Wardley AM, Kaufman B, Stemmer SM, PГЄgo A, Chan A, Goeminne JC, Graas MP, Kennedy MJ, Ciruelos Gil EM, Schneeweiss A, Zubel A, Groos J, MelezГnkovГЎ H, Awada A.
J Clin Oncol. 2013 Jul 10,31(20):2586-92. doi: 10.1200/JCO.2012.46.2408. Epub 2013 Jun 3.
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Circulating tumor DNA to monitor metastatic breast cancer.
Weiss L, Hufnagl C, Greil R.
N Engl J Med. 2013 Jul 4,369(1):93. doi: 10.1056/NEJMc1306040#SA2.
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Bevacizumab plus chemotherapy continued beyond first progression in patients with metastatic colorectal cancer previously treated with bevacizumab plus chemotherapy: ML18147 study KRAS subgroup findings.
Kubicka S, Greil R, AndrГ© T, Bennouna J, Sastre J, Van Cutsem E, von Moos R, Osterlund P, Reyes-Rivera I, MГјller T, Makrutzki M, Arnold D
Ann Oncol. 2013 Sep,24(9):2342-9. doi: 10.1093/annonc/mdt231. Epub 2013 Jul 12.
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Phase III trial of sunitinib in combination with capecitabine versus capecitabine monotherapy for the treatment of patients with pretreated metastatic breast cancer.
Crown JP, DiГ©ras V, Staroslawska E, Yardley DA, Bachelot T, Davidson N, Wildiers H, Fasching PA, Capitain O, Ramos M, Greil R, Cognetti F, Fountzilas G, Blasinska-Morawiec M, Liedtke C, Kreienberg R, Miller WH Jr, Tassell V, Huang X, Paolini J, Kern KA, Romieu G.
J Clin Oncol. 2013 Aug 10,31(23):2870-8. doi: 10.1200/JCO.2012.43.3391. Epub 2013 Jul 15.
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The predictive impact of body mass index on the efficacy of extended adjuvant endocrine treatment with anastrozole in postmenopausal patients with breast cancer: an analysis of the randomised ABCSG-6a trial.
Gnant M, Pfeiler G, Stöger H, Mlineritsch B, Fitzal F, Balic M, Kwasny W, Seifert M, Stierer M, Dubsky P, Greil R, Steger G, Samonigg H, Fesl C, Jakesz R.
Br J Cancer. 2013 Aug 6,109(3):589-96. doi: 10.1038/bjc.2013.367. Epub 2013 Jul 18.
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The clinical potential of temsirolimus in second or later lines of treatment for metastatic renal cell carcinoma.
Stenner-Liewen F, GrГјnwald V, Greil R, Porta C.
Expert Rev Anticancer Ther. 2013 Sep,13(9):1021-33. doi: 10.1586/14737140.2013.833684. Epub 2013 Sep 12.
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Neoadjuvant chemotherapy and targeted therapy in breast cancer: past, present and future.
Gampenrieder SP, Rinnerthaler G, Greil R.
J Oncol. 2013,2013:732047. doi: 10.1155/2013/732047. Epub 2013 Aug 20.
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[Successful cancer therapy: chance and challenges].
Greil R, Hiddemann W.
Dtsch Med Wochenschr. 2013 Oct,138(41):2083. doi: 10.1055/s-0033-1349623. Epub 2013 Oct 1.
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[71-year old woman with neutropenic fever during chemotherapy].
Schlick K, Datz L, Hohla F, Greil R, Hopfinger G.
Dtsch Med Wochenschr. 2013 Oct,138(41):2091-2. doi: 10.1055/s-0033-1349528. Epub 2013 Oct 1.
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The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2- breast cancer patients.
Dubsky P, Brase JC, Jakesz R, Rudas M, Singer CF, Greil R, Dietze O, Luisser I, Klug E, Sedivy R, Bachner M, Mayr D, Schmidt M, Gehrmann MC, Petry C, Weber KE, Fisch K, Kronenwett R, Gnant M, Filipits M
Br J Cancer. 2013 Dec 10,109(12):2959-64. doi: 10.1038/bjc.2013.671. Epub 2013 Oct 24.
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Systemic effect of catumaxomab in a patient with metastasized colorectal cancer: a case report.
Bezan A, Hohla F, Meissnitzer T, Greil R.
BMC Cancer. 2013 Dec 31,13:618. doi: 10.1186/1471-2407-13-618.
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Everolimus in postmenopausal, hormone receptor-positive advanced breast cancer: summary and results of an austrian expert panel discussion.
Gnant M, Greil R, Hubalek M, Steger G.
Breast Care (Basel). 2013 Aug,8(4):293-9. doi: 10.1159/000354121. Review.
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Influence of Body Mass Index on survival in indolent and Mantle-cell Lymphomas: Analysis of the StiL1 trial
Weiss, L, Melchardt, T, Egle, A, Hopfinger, G, Greil, R, Barth, J, Rummel, M
ONKOLOGIE. 2013, 36: 31-32.
What’s new in Hodgkin’s lymphoma: ASH 2012 and more
Melchardt, T, Weiss, L, Greil, R, Egle, A,
Magazine of European Medical Oncology. 2013, Volume 6, Issue 3: 193-196.
Viral infections and their management in patients with chronic lymphocytic leukemia.
Melchardt T, Weiss L, Greil R, Egle A.
Leuk Lymphoma. 2013 Aug,54(8):1602-13. doi: 10.3109/10428194.2012.755178. Epub 2013 Jan 3.
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Use of romiplostim allows for hepatitis C therapy in a HIV/HCV coinfected patient.
Taylor N, Melchardt T, Grundbichler M, Strasser M, Egle A, Greil R.
Ann Hematol. 2013 Jul,92(7):1001-2. doi: 10.1007/s00277-012-1659-z. Epub 2012 Dec 28.
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Azacitidine in patients with WHO-defined AML - results of 155 patients from the Austrian Azacitidine Registry of the AGMT-Study Group.
Pleyer L, Stauder R, Burgstaller S, Schreder M, Tinchon C, Pfeilstocker M, Steinkirchner S, Melchardt T, Mitrovic M, Girschikofsky M, Lang A, Krippl P, Sliwa T, Egle A, Linkesch W, Voskova D, Angermann H, Greil R.
J Hematol Oncol. 2013 Apr 29,6:32. doi: 10.1186/1756-8722-6-32.
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Cobas ampliprep/cobas TaqMan HIV-1 v2.0 assay: consequences at the cohort level.
Taylor N, Grabmeier-Pfistershammer K, Egle A, Greil R, Rieger A, Ledergerber B, Oberkofler H.
PLoS One. 2013 Aug 30,8(8):e74024. doi: 10.1371/journal.pone.0074024. eCollection 2013.
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Complications of 5-azacytidine: Three cases of severe ischemic colitis in elderly patients with myelodysplastic syndrome.
Melchardt T, Weiss L, Pleyer L, Steinkirchner S, Auberger J, Hopfinger G, Greil R, Egle A.
Oncol Lett. 2013 Dec,6(6):1756-1758. Epub 2013 Oct 15.
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CD40-mediated activation of chronic lymphocytic leukemia cells promotes their CD44-dependent adhesion to hyaluronan and restricts CCL21-induced motility.
Girbl T, Hinterseer E, Grössinger EM, Asslaber D, Oberascher K, Weiss L, Hauser-Kronberger C, Neureiter D, Kerschbaum H, Naor D, Alon R, Greil R, Hartmann TN.
Cancer Res. 2013 Jan 15,73(2):561-70. doi: 10.1158/0008-5472.CAN-12-2749. Epub 2012 Nov 1.
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Tiam1/Rac1 signals contribute to CLL cell proliferation and chemoresistance
Hofbauer, SW, Krenn, PW, Ganghammer, S, Asslaber, D, Pichler, U, Wallner, M, Henschler, R, Greil, R, Hartmann, TN
ONKOLOGIE. 2013, 36: 56-56.
CXCR3 modulates CXCL12-mediated cellular responses in chronic lymphocytic leukemia
Ganghammer, S, Hinterseer, E, Johrer, K, Greil, R, Hartmann, TN
CYTOKINE. 2013, 63(3): 264-264.
Antiapoptotic effects of p21 regarding its subcellular localization in arsenic trioxide induced apoptosis in CLL
Sifft, E, Hofbauer, JP, Asslaber, D, Hartmann, TN, Merkel, O, Greil, R
ONKOLOGIE. 2013, 36: 222-222.
Mimicking the microenvironment in chronic lymphocytic leukaemia - where does the journey go?
Asslaber D, Grössinger EM, Girbl T, Hofbauer SW, Egle A, Weiss L, Greil R, Hartmann TN.
Br J Haematol. 2013 Mar,160(5):711-4. doi: 10.1111/bjh.12151. Epub 2012 Dec 4.
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The transcription factor IRF-4 is related to prognosis in Chronic Lymphocytic Leukemia (CLL) and involved in proliferation and survival
Asslaber, D, Hofbauer, JP, Zaborsky, N, Kocher, T, Hartmann, TN, Greil, R, Egle, A
ONKOLOGIE. 2013, 36: 222-223.
Blockade of the Potassium Channel KCa3.1 inhibits proliferation in Chronic Lymphocytic Leukemia
Grossinger, EM, Weiss, L, Zierler, S, Hinterseer, E, Schmolzer, J, Asslaber, D, Hainzl, S, Egle, A, Pinon, JD, Hartmann, TN, Greil, R, Kerschbaum, HH
ONKOLOGIE. 2013, 36: 191-192.
A modified Phenol-chloroform extraction method for isolating circulating cell free DNA of tumor patients.
Hufnagl C, Stöcher M, Moik M, Geisberger R, Greil R.
Journal of Nucleic Acids Investigation. 2013. DOI: 10.4081/jnai.2013.e1
Lenalidomide/Rituximab Maintenance After Induction With Fludarabine/Rituximab In Combination With Escalating Doses Of Lenalidomide In Previously Untreated Chronic Lymphocytic Leukemia (CLL): The Revlirit CLL5 AGMT Phase I/II Study, Final Results
Vornamen sind ausgeschrieben-Г¤ndern? Alexander Egle, Michael Steurer, Franz Josef Gassner, Roland Geisberger, Thomas Melchardt, Lisa Pleyer, Lukas Weiss, Michael A. Fridrik, Josef Thaler, Alois Lang, Richard Greil,
Blood (ASH Annual Meeting Abstracts). 2013. #4164:
Dendritic Cells Activated by IFN-?/STAT1 Express IL-31 Receptor and Release Proinflammatory Mediators upon IL-31 Treatment.
Horejs-Hoeck J, Schwarz H, Lamprecht S, Maier E, Hainzl S, Schmittner M, Posselt G, Stoecklinger A, Hawranek T, Duschl A.
J Immunol. 2012 Jun 1,188(11):5319-26. doi: 10.4049/jimmunol.1101044. Epub 2012 Apr 25.
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PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, Schiefer AI, Hassler MR, Heider S, Amenitsch L, Thallinger C, Staber PB, Simonitsch-Klupp I, Artaker M, Lagger S, Turner SD, Pileri S, Piccaluga PP, Valent P, Messana K, Landra I, Weichhart T, Knapp S, Shehata M, Todaro M, Sexl V, Höfler G, Piva R, Medico E, Ruggeri BA, Cheng M, Eferl R, Egger G, Penninger JM, Jaeger U, Moriggl R, Inghirami G, Kenner L.
Nat Med. 2012 Nov,18(11):1699-704. doi: 10.1038/nm.2966. Epub 2012 Oct 14.
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Upgraded Cobas TaqMan version 2: hidden consequences at cohort level
Taylor, N, Grabmeier-Pfistershammer, K, Oberkofler, H, Egle, A, Rieger, A, Ledergerber, B
J INT AIDS SOC. 2012, 15: 109-109.
First Interim Efficacy and Safety Analysis of an International Phase III Randomized Trial in Newly Diagnosed Systemic Peripheral T-Cell Lymphoma Treated with Chemotherapy with or without Alemtuzumab and Consolidated by High Dose Therapy
dxxxAmore, F, Leppa, S, da Silva, MC, Relander, T, Brown, PD, Weidmann, E, Lauritzsen, GF, Pezzutto, A, Van Hoof, A, van Gelder, M, Doorduijn, JK, Wu, KL, Kluin-Nelemans, JC, Lugtenburg, PJ, Jankovska, M, Merup, M, Fagerli, UM, Walewski, J, Hagberg, H, Mariz, JM, Hansen, PB, Nosslinger, T, Janssens, A, Brandefors, L, Demuynck, H, Schaafsma, MR, Christiansen, I, Salek, D, Jyrkkio, S, Prochazka, V, Zijlstra, J, Bohmer, L, Greil, R, Stevens, W, Fijnheer, R, Kooy, MV, Grube, M, Hopfinger, G, Van den Neste, E, Jantunen, E, Trumper, L, Wulf, G, Altmann, B, Ziepert, M, Loeffler, M, Toldbod, H
BLOOD. 2012, 120(21):
RITUXIMAB PLUS SUBCUTANEOUS CLADRIBINE IN PATIENTS WITH EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA OF THE MUCOSA ASSOCIATED TISSUE (MALT-LYMPHOMA): A PHASE II STUDY BY THE AGMT (ARBEITSGEMEINSCHAFT MEDIKAMENTOSE TUMORTHERAPIE)
Troch, M, Kiesewetter, B, Willenbacher, W, Willenbacher, E, Zebisch, A, Linkesch, W, Fridrik, MA, Mullauer, L, Greil, R, Raderer, M
ANN ONCOL. 2012, 23: 352-352.
IMPACT OF NUMBER OF PREVIOUS TREATMENT LINES AND PRE-TREATMENT WITH BORTEZOMIB OR LENALIDOMIDE ON EFFICACY OF BORTEZOMIB-BENDAMUSTINE-DEXAMETHASONE (BBD) IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (MM)
Ludwig, H, Kasparu, H, Leitgeb, C, Greil, R, Rauch, E, Linkesch, W, Zojer, N, Pour, L, Fillitz, M, Adam, Z
ANN ONCOL. 2012, 23: 348-349.
Bevacizumab plus chemotherapy continued beyond first progression in patients with metastatic colorectal cancer previously treated with bevacizumab plus chemotherapy: results of a randomised phase III intergroup study initiated by the AIO and AGMT (ML18147)
Greil, R, Arnold, D, Hegewisch-Becker, S, Freier, W, Steffens, CC, Bertram, M, Schlichting, C, Andel, J, Taylor, M, Makrutzki, M, Kubicka, S
ONKOLOGIE. 2012, 35: 254-254.
Influence of the American ODAC statement upon Austrian prescription practice of bevacizumab in metastatic breast cancer
Preusser, M, Fulop, G, Berghoff, AS, Heinzl, H, Steger, GG, Greil, R, Zielinski, CC, Bartsch, R
ONKOLOGIE. 2012, 35: 66-66. und erschienen unter: Oncologist. 2012,17(7):e13-7. doi: 10.1634/theoncologist.2012-0115. Epub 2012 Jun 27.
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BIOMARKER (BM) RESULTS FROM THE PHASE III AVEREL TRIAL OF 1ST-LINE BEVACIZUMAB (BV), TRASTUZUMAB (H) plus DOCETAXEL (T) FOR HER2-POSITIVE LOCALLY RECURRENT/METASTATIC BREAST CANCER (LR/MBC)
Gianni, L, Chan, A, Mansutti, M, Pivot, X, Greil, R, Provencher, L, Prot, S, Moore, N, Scherer, SJ, Pallaud, C
ANN ONCOL. 2012, 23: 531-532.
Bevacizumab (BEV) plus chemotherapy (CT) continued beyond first progression in patients with metastatic colorectal cancer (mCRC) previously treated with BEV plus CT: Results of a randomized phase III intergroup study (TML study).
Arnold, D, Andre, T, Bennouna, J, Sastre, J, Osterlund, PJ, Greil, R, Van Cutsem, E, Von Moos, R, Reyes-Rivera, I, Bendahmane, B, Kubicka, S
J CLIN ONCOL. 2012, 30(18):
The role of biomarkers in the choice of therapy in triple negative breast cancer
Mlineritsch B Ressler S Greil R
memo - Magazine of European Medical Oncology. 2012, 5: 101-104.
A 55-year-old woman with locally advanced rectal cancer and a resectable synchronous hepatic metastasis: a case report.
Hohla, F, Mayer, P, Hutter, J, MeiГџnitzer, T, Greil, R,
memo - Magazine of European Medical Oncology. 2012, 5 (4): 273-276.
Treating T-cell lymphoma: is there a light at the end of the tunnel?
Hopfinger, G, Merkel, O, Melchardt, T, Greil, R,
Magazine of European Medical Oncology. 2012, 5 (3): 174-177.
An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy.
GrГјnwald V, Karakiewicz PI, Bavbek SE, Miller K, Machiels JP, Lee SH, Larkin J, Bono P, Rha SY, Castellano D, Blank CU, Knox JJ, Hawkins R, Anak O, Rosamilia M, Booth J, Pirotta N, Bodrogi I
Eur J Cancer. 2012 Feb,48(3):324-32. doi: 10.1016/j.ejca.2011.06.054. Epub 2011 Jul 29.
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Nilotinib as frontline and second-line therapy in chronic myeloid leukemia: open questions.
Valent P, Gastl G, Geissler K, Greil R, Hantschel O, Lang A, Linkesch W, Lion T, Petzer AL, Pittermann E, Pleyer L, Thaler J, Wolf D.
Crit Rev Oncol Hematol. 2012 Jun,82(3):370-7. doi: 10.1016/j.critrevonc.2011.08.002. Epub 2011 Sep 7.
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First-line panitumumab plus irinotecan/5-fluorouracil/leucovorin treatment in patients with metastatic colorectal cancer.
Köhne CH, Hofheinz R, Mineur L, Letocha H, Greil R, Thaler J, Fernebro E, Gamelin E, Decosta L, Karthaus M.
J Cancer Res Clin Oncol. 2012 Jan,138(1):65-72. doi: 10.1007/s00432-011-1061-6. Epub 2011 Sep 30.
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Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.
Jöhrer K, Obkircher M, Neureiter D, Parteli J, Zelle-Rieser C, Maizner E, Kern J, Hermann M, Hamacher F, Merkel O, Wacht N, Zidorn C, Scheideler M, Greil R.
J Mol Med (Berl). 2012 Jun,90(6):681-93. doi: 10.1007/s00109-011-0848-x. Epub 2011 Dec 29.
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Prognostic value of number of removed lymph nodes, number of involved lymph nodes and lymph node ratio in 7502 breast cancer patients enrolled onto trials of the Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Tausch C, Taucher S, Dubsky P, Seifert M, Reitsamer R, Kwasny W, Jakesz R, Fitzal F, Filipcic L, Fridrik M, Greil R, Gnant M.
Ann Surg Oncol. 2012 Jun,19(6):1808-17. doi: 10.1245/s10434-011-2189-y. Epub 2011 Dec 30.
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Lipid profiles for etravirine versus efavirenz in treatment-naive patients in the randomized, double-blind SENSE trial.
Fätkenheuer G, Duvivier C, Rieger A, Durant J, Rey D, Schmidt W, Hill A, van Delft Y, Marks S
J Antimicrob Chemother. 2012 Mar,67(3):685-90. doi: 10.1093/jac/dkr533. Epub 2011 Dec 29.
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Dose-intensification in early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD14 trial.
von Tresckow B, PlГјtschow A, Fuchs M, Klimm B, Markova J, Lohri A, Kral Z, Greil R, Topp MS, Meissner J, Zijlstra JM, Soekler M, Stein H, Eich HT, Mueller RP, Diehl V, Borchmann P, Engert A.
J Clin Oncol. 2012 Mar 20,30(9):907-13. doi: 10.1200/JCO.2011.38.5807. Epub 2012 Jan 23.
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Tamoxifen and anastrozole as a sequencing strategy: a randomized controlled trial in postmenopausal patients with endocrine-responsive early breast cancer from the Austrian Breast and Colorectal Cancer Study Group.
Dubsky PC, Jakesz R, Mlineritsch B, Pöstlberger S, Samonigg H, Kwasny W, Tausch C, Stöger H, Haider K, Fitzal F, Singer CF, Stierer M, Sevelda P, Luschin-Ebengreuth G, Taucher S, Rudas M, Bartsch R, Steger GG, Greil R, Filipcic L, Gnant M.
J Clin Oncol. 2012 Mar 1,30(7):722-8. doi: 10.1200/JCO.2011.36.8993. Epub 2012 Jan 23.
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First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: results of a prospective, randomized phase III study.
Bergh J, Bondarenko IM, Lichinitser MR, Liljegren A, Greil R, Voytko NL, Makhson AN, Cortes J, Lortholary A, Bischoff J, Chan A, Delaloge S, Huang X, Kern KA, Giorgetti C.
J Clin Oncol. 2012 Mar 20,30(9):921-9. doi: 10.1200/JCO.2011.35.7376. Epub 2012 Feb 13.
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[Primary immune thrombocytopenia in adults: diagnostics and treatment consensus statement of the Austrian Society of Hematology and Oncology (ÖGHO)].
Pabinger I, Gastl G, Steurer M, Sormann S, Fillitz M, Friedl J, Geissler D, Geissler K, Greil R, Knöbl P, Kozek-Langenecker S, Krippl P, Kyrle P, Lang A, Linkesch W, Ludwig H, Müller M, Panzer S, Pittermann E, Thaler J, Weltermann A.
Wien Klin Wochenschr. 2012 Feb,124(3-4):111-23. doi: 10.1007/s00508-012-0123-3. Epub 2012 Mar 3.
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The effect of guideline-consistent antiemetic therapy on chemotherapy-induced nausea and vomiting (CINV): the Pan European Emesis Registry (PEER).
Aapro M, Molassiotis A, Dicato M, PelГЎez I, RodrГguez-Lescure ГЃ, Pastorelli D, Ma L, Burke T, Gu A, Gascon P, Roila F
Ann Oncol. 2012 Aug,23(8):1986-92. Epub 2012 Mar 6.
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Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label phase 3 non-inferiority trial.
Engert A, Haverkamp H, Kobe C, Markova J, Renner C, Ho A, Zijlstra J, Král Z, Fuchs M, Hallek M, Kanz L, Döhner H, Dörken B, Engel N, Topp M, Klutmann S, Amthauer H, Bockisch A, Kluge R, Kratochwil C, Schober O, Greil R, et al.
Lancet. 2012 May 12,379(9828):1791-9. doi: 10.1016/S0140-6736(11)61940-5. Epub 2012 Apr 4.
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LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases: a randomized, placebo-controlled multicenter multinational double-blinded phase II trial.
Schimanski CC, Möhler M, Schön M, van Cutsem E, Greil R, Bechstein WO, Hegewisch-Becker S, von Wichert G, Vöhringer M, Heike M, Heinemann V, Peeters M, Kanzler S, Kasper S, Overkamp F, Schröder J, Seehofer D, Kullmann F, Linz B, Schmidtmann I, Smith-Machnow V, Gockel I, et al.
BMC Cancer. 2012 Apr 11,12:144. doi: 10.1186/1471-2407-12-144.
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Rituximab serum concentrations during immuno-chemotherapy of follicular lymphoma correlate with patient gender, bone marrow infiltration and clinical response.
Jäger U, Fridrik M, Zeitlinger M, Heintel D, Hopfinger G, Burgstaller S, Mannhalter C, Oberaigner W, Porpaczy E, Skrabs C, Einberger C, Drach J, Raderer M, Gaiger A, Putman M, Greil R
Haematologica. 2012 Sep,97(9):1431-8. Epub 2012 Apr 17.
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Continuous lenalidomide treatment for newly diagnosed multiple myeloma.
Palumbo A, Hajek R, Delforge M, Kropff M, Petrucci MT, Catalano J, Gisslinger H, Wiktor-J?drzejczak W, Zodelava M, Weisel K, Cascavilla N, Iosava G, Cavo M, Kloczko J, BladГ© J, Beksac M, Spicka I, Plesner T, Radke J, Langer C, Ben Yehuda D, Corso A, et al.
N Engl J Med. 2012 May 10,366(19):1759-69. doi: 10.1056/NEJMoa1112704.
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Safety results from a phase III study (TURANDOT trial by CECOG) of first-line bevacizumab in combination with capecitabine or paclitaxel for HER-2-negative locally recurrent or metastatic breast cancer.
Lang I, Inbar MJ, KahГЎn Z, Greil R, Beslija S, Stemmer SM, Kaufman B, Zvirbule Z, Steger GG, Messinger D, Brodowicz T, Zielinski C.
Eur J Cancer. 2012 Nov,48(17):3140-9. doi: 10.1016/j.ejca.2012.04.022. Epub 2012 May 26.
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Influence of the American ODAC statement on Austrian bevacizumab prescribing practice for metastatic breast cancer.
Preusser M, Fülöp G, Berghoff AS, Heinzl H, Steger GG, Greil R, Zielinski CC, Bartsch R.
Oncologist. 2012,17(7):e13-7. doi: 10.1634/theoncologist.2012-0115. Epub 2012 Jun 27.
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[Safety of immunosuppressants].
Psenak O, Studnicka-Benke A, Greil R.
Z Rheumatol. 2012 Jul,71(5):420-9. doi: 10.1007/s00393-012-0990-z.
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Effect of KRAS codon13 mutations in patients with advanced colorectal cancer (advanced CRC) under oxaliplatin containing chemotherapy. Results from a translational study of the AIO colorectal study group.
Reinacher-Schick A, Schulmann K, Modest DP, Bruns N, Graeven U, Jaworska M, Greil R, Porschen R, Arnold D, Schmiegel W, Tannapfel A.
BMC Cancer. 2012 Aug 9,12:349. doi: 10.1186/1471-2407-12-349.
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Novel treatment avenues for peripheral T-cell lymphomas.
Hopfinger G, Griessl R, Sifft E, Taylor N, Kenner L, Greil R, Merkel O.
Expert Opin Drug Discov. 2012 Dec,7(12):1149-63. doi: 10.1517/17460441.2012.727392. Epub 2012 Sep 24.
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Skin toxicity and quality of life in patients with metastatic colorectal cancer during first-line panitumumab plus FOLFIRI treatment in a single-arm phase II study.
Thaler J, Karthaus M, Mineur L, Greil R, Letocha H, Hofheinz R, Fernebro E, Gamelin E, Baños A, Köhne CH.
BMC Cancer. 2012 Sep 29,12:438. doi: 10.1186/1471-2407-12-438.
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What paths are open for tackling increasing azole resistance in Aspergillus in the clinic?
Auberger J, Greil R, Lass-Flörl C.
Expert Rev Anti Infect Ther. 2012 Nov,10(11):1229-31. doi: 10.1586/eri.12.126.
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Treating T-cell lymphoma: is there a light at the end of the tunnel?
Hopfinger G, Merkel O, Melchardt T, Greil R.
Memo - Magazine of European Medical Oncology. (2012) 5:174–177 DOI 10.1007/s12254-012-0013-4
AOP2014, a Novel Peg-Proline-Interferon Alpha-2b with Improved Pharmacokinetic Properties, Is Safe and Well Tolerated and Shows Promising Efficacy in Patients with Polycythemia Vera (PV)
Gisslinger, H, Kralovics, R, Gisslinger, B, Lechner, D, Buxhofer-Ausch, V, Strecker, K, Gastl, G, Willenbacher, E, Greil, R, Egle, A, Melchardt, T, Burgstaller, S, Schloegl, E, Tarmann, FJ, Zoerer, M, Klade, C, Zahriychuk, O, Thaler, J
BLOOD. 2012, 120(21):
Treatment of Aggressive B-Cell Lymphoma in the Elderly: The Influence of SNPs Affecting Pharmacodynamics Is Different Compared to Younger Patient
Melchardt, T, Weiss, L, Hufnagl, C, Neureiter, D, Kemmerling, R, Morre, P, Boekstegers, A, Hopfinger, G, Greil, R, Egle, A
BLOOD. 2012, 120(21):
Complications of 5-azacytidine: Three cases of severe colitis in a single center cohort
Melchardt, T, Weiss, L, Pleyer, L, Steinkirchner, S, Greil, R, Egle, A
ONKOLOGIE. 2012, 35: 149-149.
Feasibility of anthracycline based treatment in unselected elderly DLBCL patients
Melchardt, T, Weiss, L, Hufnagl, C, Neureiter, D, Kemmerling, R, Hopfinger, G, Greil, R, Egle, A
ONKOLOGIE. 2012, 35: 86-87.
Treatment of Aggressive B-Cell Lymphoma in the Elderly: The Influence of SNPs Affecting Pharmacodynamics Is Different Compared to Younger Patient
Thomas Melchardt, Lukas Weiss, Clemens Hufnagl, Daniel Neureiter, Ralf Kemmerling, Patrick Morre, Ann Boekstegers, Georg Hopfinger, Richard Greil, Alexander Egle,
Blood (ASH Annual Meeting Abstracts) 2012. 2012. #1613:
Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia.
Merkel O, Wacht N, Sifft E, Melchardt T, Hamacher F, Kocher T, Denk U, Hofbauer JP, Egle A, Scheideler M, Schlederer M, Steurer M, Kenner L, Greil R.
Leukemia. 2012 Dec,26(12):2508-16. doi: 10.1038/leu.2012.147. Epub 2012 Jun 1.
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Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?
Jöhrer K, Hofbauer SW, Zelle-Rieser C, Greil R, Hartmann TN.
Expert Opin Biol Ther. 2012 Apr,12(4):425-41. doi: 10.1517/14712598.2012.664128. Epub 2012 Feb 15.
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Canonical and noncanonical Hedgehog/GLI signaling in hematological malignancies.
Aberger F, Kern D, Greil R, Hartmann TN.
Vitam Horm. 2012,88:25-54. doi: 10.1016/B978-0-12-394622-5.00002-X.
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Lysine residue at position 22 of the AID protein regulates its class switch activity.
Geisberger R, Huemer M, Gassner FJ, Zaborsky N, Egle A, Greil R.
PLoS One. 2012,7(2):e30667. doi: 10.1371/journal.pone.0030667. Epub 2012 Feb 20.
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Anaplastic large cell lymphoma: the current state of play from a European prospective as presented at the second annual meeting of the European Research Initiative on ALCL, 27-28 June 2011.
Merkel O, Kenner L, Turner SD.
Leukemia. Dec,25(12):1795-6. doi: 10.1038/leu.2011.295.
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Clinical aspects of 2009 pandemic influenza A (H1N1) virus infection in Austria.
Poeppl, W, Hell, M, Herkner, H, Stoiser, B, Fritsche, G, Schurz-Bamieh, N, Poeppl, G, Gattringer, R, Jones, N, Maass, M, Egle, A, Burgmann, H,
Infection. 2011 Aug,39(4):341-52. doi: 10.1007/s15010-011-0121-9. Epub 2011 May 5.
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R-CHOP plus thalidomide for previously untreated patients with mantle cell lymphoma (AGMT NHL-11 trial)
Drach, J, Hopfinger, G, Fridrik, M, Greil, R, Thaler, J, Willenbacher, W, Lang, A, Jager, U, Raderer, M
ONKOLOGIE. 2011, 34: 75-75.
DOSE-ESCALATION WITH BEACOPP ESCALATED IS SUPERIOR TO ABVD IN THE COMBINED-MODALITY TREATMENT OF EARLY UNFAVORABLE HODGKIN LYMPHOMA (HL): FINAL ANALYSIS OF THE GERMAN HODGKIN STUDY GROUP (GHSG) HD14 TRIAL
Borchmann, P, Diehl, V, Plutschow, A, Von Tresckow, B, Markova, J, Hitz, F, Kra, Z, Greil, R, Topp, MS, Villalobos, M, Zijlstra, JM, Sokler, M, Fuchs, M, Engert, A
ANN ONCOL. 2011, 22: 180-180.
Lower incidence of BCR-ABL mutations and improved molecular response kinetics in newly diagnosed CML patients treated with nilotinib compared with imatinib
Muller, MC, le Coutre, P, Gattermann, N, Scheid, C, Al-Ali, HK, Ottmann, OG, Duyster, J, Blumenstengel, K, Brummendorf, TH, Greil, R, Chalandon, Y, Valent, P, Stegelmann, F, Kneba, M, Schafhausen, P, Saussele, S, Frank, O, Larson, RA, Saglio, G, Hochhaus, A, Lange, T
ONKOLOGIE. 2011, 34: 266-266.
62-Month follow-up of ABCSG-12: Adjuvant endocrine therapy, alone or in combination with zoledronic acid, in premenopausal patients with endocrine-responsive early breast cancer
Gnant, M, Mlineritsch, B, Stoeger, H, Luschin-Ebengreuth, G, Poestlberger, S, Steger, G, Jakesz, R, Singer, C, Eidtmann, H, Greil, R
BONE. 2011, 48(1): S17-S17.
The oncogenic miR-17-92 cluster and miR-155 define ALK status in anaplastic large cell lymphoma
Griessl, R, Hamacher, F, Sifft, E, Scheideler, M, Kenner, L, Greil, R, Merkel, O
ONKOLOGIE. 2011, 34: 135-135.
Parp Inhibitoren
Ressler Sigrun, Mlineritsch Brigitte, Greil Richard
Universum Innere Medizin. 2011.
Bisphosphonate in der Therapie des Mammakarzinoms
Ressler Sigrun, Mlineritsch Brigitte, Greil Richard
MEDIUM. 2011. 3: 26-30.
Bedeutung des RANK / RANK-Ligand Systems beim Mammakarzinom: Biologische Grundlagen.
Ressler Sigrun, Mlineritsch Brigitte, Greil Richard
Universum Innere Medizin. 2011.
Liposomal cytarabine is effective and tolerable in the treatment of central nervous system relapse of acute lymphoblastic leukemia and very aggressive lymphoma.
Gökbuget N, Hartog CM, Bassan R, Derigs HG, Dombret H, Greil R, Hernández-Rivas JM, Huguet F, Intermesoli T, Jourdan E, Junghanss C, Leimer L, Moreno MJ, Reichle A, Ribera J, Schmid M, Serve H, Stelljes M, Stuhlmann R, Hoelzer D
Haematologica. 2011 Feb,96(2):238-44. doi: 10.3324/haematol.2010.028092. Epub 2010 Oct 15.
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Infusion reactions to the chimeric EGFR inhibitor cetuximab--change to the fully human anti-EGFR monoclonal antibody panitumumab is safe.
Resch G, Schaberl-Moser R, Kier P, Kopetzky G, Scheithauer W, Sliwa T, Greil R, Nösslinger T, Mayrbäurl B, Thaler J.
Ann Oncol. 2011 Feb,22(2):486-7. doi: 10.1093/annonc/mdq744. Epub 2011 Jan 13.
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Preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with newly diagnosed primary operable cT₃NxM0 low rectal cancer: a phase II study.
Ofner D, Devries AF, Schaberl-Moser R, Greil R, Rabl H, Tschmelitsch J, Zitt M, Kapp KS, Fastner G, Keil F, Eisterer W, Jäger R, Offner F, Gnant M, Thaler J
Strahlenther Onkol. 2011 Feb,187(2):100-7. doi: 10.1007/s00066-010-2182-6. Epub 2011 Jan 21.
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Successful alemtuzumab retreatment in progressive B-cell chronic lymphocytic leukemia: a multicenter survey in 30 patients.
Fiegl M, Falkner F, Steurer M, Zojer N, Hopfinger G, Haslbauer F, Winder G, Voskova D, Andel J, Lang A, Brychtova Y, Mayer J, Greil R, Gastl G
Ann Hematol. 2011 Sep,90(9):1083-91. doi: 10.1007/s00277-011-1192-5. Epub 2011 Feb 25.
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Zoledronic acid for adjuvant use in patients with breast cancer.
Ressler S, Mlineritsch B, Greil R.
Expert Rev Anticancer Ther. 2011 Mar,11(3):333-49. doi: 10.1586/era.11.13.
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Sentinel node biopsy after primary chemotherapy in breast cancer: a note of caution from results of ABCSG-14.
Tausch C, Steger GG, Haid A, Jakesz R, Fridrik MA, Reitsamer R, Pöstlberger S, Lang A, Gnant M, Greil R.
Breast J. 2011 May-Jun,17(3):230-8. doi: 10.1111/j.1524-4741.2011.01073.x. Epub 2011 Mar 31.
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Clinical outcome with bevacizumab in patients with recurrent high-grade glioma treated outside clinical trials.
Hofer S, Elandt K, Greil R, Hottinger AF, Huber U, Lemke D, Marosi C, Ochsenbein A, Pichler J, Roelcke U, Weder P, Zander T, Wick W, Weller M.
Acta Oncol. 2011 Jun,50(5):630-5. doi: 10.3109/0284186X.2011.572913. Epub 2011 Apr 18.
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Impact of body mass index on the efficacy of endocrine therapy in premenopausal patients with breast cancer: an analysis of the prospective ABCSG-12 trial.
Pfeiler G, Königsberg R, Fesl C, Mlineritsch B, Stoeger H, Singer CF, Pöstlberger S, Steger GG, Seifert M, Dubsky P, Taucher S, Samonigg H, Bjelic-Radisic V, Greil R, Marth C, Gnant M.
J Clin Oncol. 2011 Jul 1,29(19):2653-9. doi: 10.1200/JCO.2010.33.2585. Epub 2011 May 9.
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Combination therapy of lapatinib and Capecitabine for ErbB2-positive metastatic or locally advanced breast cancer: results from the Lapatinib Expanded Access Program (LEAP) in Central and Eastern Europe.
Greil R, BorГ…ВЎtnar S, PetrГЎkovГЎ K, Marcou Y, Pikiel J, Wojtukiewicz MZ, Koza I, Steger GG, Linn M, Das Gupta A, Cwiertka K.
Onkologie. 2011,34(5):233-8. doi: 10.1159/000327710. Epub 2011 Apr 26.
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Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer.
Grundbichler M, Mlineritsch B, Ressler S, Moik M, Kappacher A, Rosenlechner S, Greil R.
Oncology. 2011,80(1-2):34-41. doi: 10.1159/000328086. Epub 2011 May 23.
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Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 62-month follow-up from the ABCSG-12 randomised trial.
Gnant M, Mlineritsch B, Stoeger H, Luschin-Ebengreuth G, Heck D, Menzel C, Jakesz R, Seifert M, Hubalek M, Pristauz G, Bauernhofer T, Eidtmann H, Eiermann W, Steger G, Kwasny W, Dubsky P, Hochreiner G, Forsthuber EP, Fesl C, Greil R
Lancet Oncol. 2011 Jul,12(7):631-41. doi: 10.1016/S1470-2045(11)70122-X. Epub 2011 Jun 5.
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Randomized phase II study of lapatinib plus capecitabine or lapatinib plus topotecan for patients with HER2-positive breast cancer brain metastases.
Lin NU, Eierman W, Greil R, Campone M, Kaufman B, Steplewski K, Lane SR, Zembryki D, Rubin SD, Winer EP.
J Neurooncol. 2011 Dec,105(3):613-20. doi: 10.1007/s11060-011-0629-y. Epub 2011 Jun 26.
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Novel therapeutic options in anaplastic large cell lymphoma: molecular targets and immunological tools.
Merkel O, Hamacher F, Sifft E, Kenner L, Greil R
Mol Cancer Ther. 2011 Jul,10(7):1127-36. doi: 10.1158/1535-7163.MCT-11-0042. Epub 2011 Jun 28. Review.
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Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Davies C, Godwin J, Gray R, Clarke M, Cutter D, Darby S, McGale P, Pan HC, Taylor C, Wang YC, Dowsett M, Ingle J, Peto R.
Lancet. 2011 Aug 27,378(9793):771-84. doi: 10.1016/S0140-6736(11)60993-8. Epub 2011 Jul 28.
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A new molecular predictor of distant recurrence in ER-positive, HER2-negative breast cancer adds independent information to conventional clinical risk factors.
Filipits M, Rudas M, Jakesz R, Dubsky P, Fitzal F, Singer CF, Dietze O, Greil R, Jelen A, Sevelda P, Freibauer C, Müller V, Jänicke F, Schmidt M, Kölbl H, Rody A, Kaufmann M, Schroth W, Brauch H, Schwab M, Fritz P, Weber KE, et al.
PLoS One. 2011,6(8):e23758. doi: 10.1371/journal.pone.0023758. Epub 2011 Aug 18
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Eight cycles of escalated-dose BEACOPP compared with four cycles of escalated-dose BEACOPP followed by four cycles of baseline-dose BEACOPP with or without radiotherapy in patients with advanced-stage hodgkin's lymphoma: final analysis of the HD12 trial of the German Hodgkin Study Group.
Borchmann P, Haverkamp H, Diehl V, Cerny T, Markova J, Ho AD, Eich HT, Mueller-Hermelink HK, Kanz L, Greil R, Rank A, Paulus U, Smardova L, Huber C, Dörken B, Nerl C, Krause SW, Mueller RP, Fuchs M, Engert A.
J Clin Oncol. 2011 Nov 10,29(32):4234-42. doi: 10.1200/JCO.2010.33.9549. Epub 2011 Oct 11.
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Adjuvant sequencing of tamoxifen and anastrozole is superior to tamoxifen alone in postmenopausal women with low proliferating breast cancer.
Bago-Horvath Z, Rudas M, Dubsky P, Jakesz R, Singer CF, Kemmerling R, Greil R, Jelen A, Böhm G, Jasarevic Z, Haid A, Gruber C, Pöstlberger S, Filipits M, Gnant M
Clin Cancer Res. 2011 Dec 15,17(24):7828-34. doi: 10.1158/1078-0432.CCR-11-1846. Epub 2011 Oct 13.
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Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Darby S, McGale P, Correa C, Taylor C, Arriagada R, Clarke M, Cutter D, Davies C, Ewertz M, Godwin J, Gray R, Pierce L, Whelan T, Wang Y, Peto R.
Lancet. 2011 Nov 12,378(9804):1707-16. doi: 10.1016/S0140-6736(11)61629-2. Epub 2011 Oct 19. Review.
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Oxaliplatin, irinotecan and cetuximab in advanced gastric cancer. A multicenter phase II trial (Gastric-2) of the Arbeitsgemeinschaft Medikamentose Tumortherapie (AGMT).
Wöll E, Greil R, Eisterer W, Bechter O, Fridrik MA, Grünberger B, Zabernigg A, Mayrbäurl B, Russ G, Dlaska M, Obrist P, Thaler J.
Anticancer Res. 2011 Dec,31(12):4439-43.
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ASH Report. Novel agents in diffuse large B-cell lymphoma: A short update including ASH 2010.
Melchardt T, Hofbauer SW, Greil R, Hopfinger G.
Memo - Magazine of European Medical Oncology. 2011 June 1, 4(2): 120-123.
Clonal Diversity of the T Cell Repertoire Predicts Disease Progression in Chronic Lymphocytic Leukaemia
Holler, C, Zaborsky, N, Hofbauer, JP, Kocher, T, Trapin, D, Asslaber, D, Greil, R, Egle, A
BLOOD. 2011, 118(21): 365-365.
CLL CELLS INDUCE CLONAL T CELL SKEWING AND SUBSETSHIFTING IN THE MURINE TCL1 TRANSGENIC CHRONIC LYMPHOCYTIC LEUKEMIA MODEL
Egle, A, Pinon-Hofbauer, J, Heyder, C, Denk, U, Kocher, T, Holler, C, Trapin, D, Asslaber, D, Tinhofer, I, Greil, R
ANN ONCOL. 2011, 22: 144-144.
Tumor load reduction and prolongation of overall-survival by actinomycin D in a murine model of high-risk chronic lymphocytic leukemia
Wacht, N, Sifft, E, Melchardt, T, Hamacher, F, Denk, U, Pinon-Hofbauer, J, Egle, A, Kocher, T, Steurer, M, Greil, R, Merkel, O
ONKOLOGIE. 2011, 34: 141-141.
Open-Label, Prospective, Multicentre, Phase I/II Study of AOP2014, a Novel PEG-Proline-Interferon Alpha-2b in Patients with Polycythemia Vera: Update from an Ongoing Study
Gisslinger, H, Kralovics, R, Schoder, R, Gisslinger, B, Buxhofer-Ausch, V, Strecker, K, Wolf, D, Willenbacher, E, Greil, R, Egle, A, Melchardt, T, Burgstaller, S, Tarmann, FJ, Wachter, C, Zahriycick, O, Thaler, J
BLOOD. 2011, 118(21): 762-762.
Activity of Azacitidine in 26 Unselected, Consecutive CMML Patients Included in the Austrian Azacitidine Registry (AAR) of the AGMT-Study Group
Pleyer, L, Stauder, R, Burgstaller, S, Schreder, M, Tinchon, C, Pfeilstocker, M, Steinkirchner, S, Melchardt, T, Mitrovic, M, Girschikofsky, M, Lang, A, Krippl, P, Egle, A, Sliwa, T, Linkesch, W, Fridrik, MA, Greil, R
BLOOD. 2011, 118(21): 747-747.
Treatment of invasive aspergillosis in cancer patients.
Auberger, J, Russ, G, Greil, R, Egle, A,
memo - Magazine of European Medical Oncology. 2011, 4 (4): 266-272.
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15,117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18.
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Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Hofbauer JP, Heyder C, Denk U, Kocher T, Holler C, Trapin D, Asslaber D, Tinhofer I, Greil R, Egle A.
Leukemia. 2011 Sep,25(9):1452-8. doi: 10.1038/leu.2011.111. Epub 2011 May 24.
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Raltegravir in pregnancy: a case series presentation.
Taylor N, Touzeau V, Geit M, Gisinger M, Egle A, Greil R, Rieger A, Zangerle R.
Int J STD AIDS. 2011 Jun,22(6):358-60. doi: 10.1258/ijsa.2011.010469.
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Complete remission of Waldenström macroglobulinemia with azacitidine and rituximab.
Weiss L, Melchardt T, Neureiter D, Kemmerling R, Moshir S, Pleyer L, Greil R, Egle A.
J Clin Oncol. 2011 Aug 20,29(24):e696-8. doi: 10.1200/JCO.2011.35.8283. Epub 2011 Jul 5.
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CD44-hyaluronan interactions in the pathophysiology of chronic lymphocytic leukemia - regulation by cell activation
Girbl, T, Asslaber, D, Brachtl, G, Denk, U, Weiss, L, Naor, D, Greil, R, Hartmann, TN
ONKOLOGIE. 2011, 34: 140-140.
Differential bone marrow homing capacity of VLA-4 and CD38 high expressing chronic lymphocytic leukemia cells.
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011,6(8):e23758. doi: 10.1371/journal.pone.0023758. Epub 2011 Aug 18.
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A Combination of Fludarabine/Rituximab with Escalating Doses of Lenalidomide in Previously Untreated Chronic Lymphocytic Leukemia (CLL): The REVLIRIT CLL5 AGMT Phase I/II Study, Clinical and Exploratory Analyses of Induction Results
Egle, A, Steurer, M, Gassner, F, Geisberger, R, Melchardt, T, Weiss, L, Fridrik, MA, Thaler, J, Lang, A, Greil, R
BLOOD. 2011, 118(21): 135-136.
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan,60(1):75-85. doi: 10.1007/s00262-010-0920-3. Epub 2010 Sep 21.
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Riding the 2-edged sword.
Egle A.
Blood. 2010 Jun 3,115(22):4325-6. doi: 10.1182/blood-2010-03-272211.
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Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation.
Labi V, Erlacher M, Krumschnabel G, Manzl C, Tzankov A, Pinon J, Egle A, Villunger A.
Genes Dev. 2010 Aug 1,24(15):1602-7. doi: 10.1101/gad.1940210.
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CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B.
Leick M, Catusse J, Follo M, Nibbs RJ, Hartmann TN, Veelken H, Burger M.
mmunology. 2010 Apr,129(4):536-46. doi: 10.1111/j.1365-2567.2009.03209.x. Epub 2009 Dec 2.
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ÖGHO-Frühjahrstagung: Chronische Lymphatische Leukämie, Adhäsionsmoleküle als mögliche therapeutische Ziele.
Hartmann TN.
JATROS Haematologie und Onkologie. 3/2010, Seite 63-65.
Erforschung der Chronisch Lymphatischen Leukämie am LIMCR.
Hartmann TN.
Med.ium. 6/2010.
Is Liposome Encapsulated Doxorubicin Able to Reduce the Cardiotoxicity of Doxorubicin In the Treatment of DLBCL? A Randomised Study by the Austrian Working Party of Medical Oncology (AGMT-Study NHL-14)
Fridrik, M, Petzer, AL, Keil, F, Willenbacher, W, Jager, U, Lang, A, Andel, J, Krieger, O, Oberaigner, W, Greil, R
BLOOD. 2010, 116(21): 736-737.
Dose-Escalation with BEACOPP Escalated Is Superior to ABVD In the Combined-Modality Treatment of Early Unfavorable Hodgkin Lymphoma: Final Analysis of the German Hodgkin Study Group (GHSG) HD14 Trial
Engert, A, Borchmann, P, Pluetschow, A, von Tresckow, B, Markova, J, Hitz, F, Kral, Z, Greil, R, Topp, MS, Villalobos, M, Zijlstra, JM, Soekler, M, Stein, H, Eich, HT, Mueller, RP, Fuchs, M, Diehl, V
BLOOD. 2010, 116(21): 336-336.
Independent prognostic factors for response: updated results of the ABCSG-24 study evaluating the addition of capecitabine to epirubicin-docetaxel neoadjuvant therapy for early breast cancer (EBC)
Steger, GG, Greil, R, Jakesz, R, Lang, A, Mlineritsch, B, Rudas, M, Marth, C, Stoeger, H, Singer, CF, Gnant, M
EJC SUPPL. 2010, 8(3): 60-60.
Role of miRNAs in ALK(+) and ALK(-) anaplastic large cell lymphoma
Hamacher, F, Laimer, D, Scheideler, M, Trajanoski, Z, Egger, G, Kenner, L, Greil, R, Merkel, O
ONKOLOGIE. 2010, 33: 209-209.
HETEROGENEOUS EXPRESSION PATTERN OF HEDGEHOG SIGNALLING PATHWAY IN HEMATOPOIESIS OF MYELODYSPLASTIC SYNDROME
Neureiter, D, Kemmerling, R, Alinger, B, Kiesslich, T, Faber, V, Stocher, M, Pleyer, L, Greil, R, Dietz, O
HAEMATOL-HEMATOL J. 2010, 95: 375-375.
Targeting Pim-2, a novel survival protein of myeloma cells, kills malignant plasma cells
Johrer, K, Obkircher, M, Neureiter, D, Parteli, J, Hamacher, F, Merkel, O, Wacht, N, Zidorn, C, Scheideler, M, Greil, R
ONKOLOGIE. 2010, 33: 187-188.
Antiapoptotic effects of p21 in arsenic trioxide induced apoptosis in CLL
Sifft, E, Asslaber, D, Schweiggl, S, Hamacher, F, Greil, R, Merkel, O
ONKOLOGIE. 2010, 33: 185-185.
Non-pegylated liposomal doxorubicin in metastatic breast cancer (MBC) - Results from an Austrian post marketing surveillance programme
Steger, GG, Mlineritsch, B, Bartsch, R, Pluschnig, U, Petru, E, Peintinger, F, Sevelda, P, Greil, R
ONKOLOGIE. 2010, 33: 55-55.
ADJUVANT ENDOCRINE THERAPY, ALONE OR IN COMBINATION WITH ZOLEDRONIC ACID (ZOL), IN PREMENOPAUSAL PATIENTS (PTS) WITH ENDOCRINE-RESPONSIVE EARLY BREAST CANCER (EBC): SUBGROUP ANALYSES OF ABCSG-12
Gnant, M, Mlineritsch, B, Stoeger, H, Luschin-Ebengreuth, G, Poestlberger, S, Steger, GG, Jakesz, R, Singer, CF, Eidtmann, H, Greil, R
ANN ONCOL. 2010, 21: 79-79.
ABCSG-24: EFFICACY OF ANTHRACYCLINE- AND TAXANE-BASED NEOADJUVANT THERAPY +/- CAPECITABINE (C) IN TRIPLE-NEGATIVE EARLY BREAST CANCER (TNBC)
Steger, GG, Greil, R, Jakesz, R, Mlineritsch, B, Lang, A, Rudas, M, Marth, C, Stoeger, H, Singer, CF, Gnant, M
ANN ONCOL. 2010, 21: 79-79.
Essential Thrombocythemia (ET).
Pleyer, L, Faber, V, Neureiter, D, Greil, R
In: Greil, R, Pleyer, L, Neureiter, D, Faber, V (Ed.) editors(s). Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.. p. 14-50.
Introduction to „Classic' Chronic Myeloproliferative Disoderes (CMPDs)- Molecular and Cellular Biology.
Pleyer, L, Greil, R,
In: Greil, R, Pleyer, L, Neureiter, D, Faber, V (Ed.) editors(s). Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.. p. 1-13.
Clonal Bone Marrow Failure Overlap Syndromes.
Pleyer, L, Neureiter, D, Faber, V, Greil, R,
In: Greil, R, Pleyer, L, Neureiter, D, Faber, V (Ed.) editors(s). Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.. p. 281-288.
Primary Myelofibrosis (PMF) [Previously Chronic Idiopathic Mylofibrosis (CIMF), Myelofibrosis with Myeloid Metaplasia (MMM), Agnogenic Myeloid Metaplasia (AMM)].
Pleyer, L, Faber, V, Neureiter, D, Greil, R,
In: Greil, R, Pleyer, L, Neureiter, D, Faber, V (Ed.) editors(s). Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.. p. 81-116.
De novo 'Classic' Paroxysmal Nocturnal Hemoglobinuria (PNH) (Marchiafava-Micheli Syndrome).
Pleyer, L, Greil, R,
In: Greil, R, Pleyer, L, Neureiter, D, Faber, V (Ed.) editors(s). Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.. p. 259-280.
Bewegung und Krebs.
Pleyer, L, Kappacher, A, Rosenlechner, S, Greil, R,
In: Braumann, KM, Stiller, N (Ed.) editors(s). Bewegungstherapie bei internistischen Erkrankungen.. p. 223-240.
Polycythemia Vera (PV).
Pleyer, L, Neureiter, D, Greil, R,
In: Greil, R, Pleyer, L, Neureiter, D, Faber, V (Ed.) editors(s). Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.. p. 51-80.
Myelodysplastic Syndromes (MDS).
Pleyer, L, Neureiter, D, Faber, V, Greil, R,
In: Greil, R, Pleyer, L, Neureiter, D, Faber, V (Ed.) editors(s). Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.. p. 153-222.
Chronic Myelomonocytic Leukemia (CMML).
Pleyer, L, Neureiter, D, Faber, V, Greil, R,
In: Greil, R, Pleyer, L, Neureiter, D, Faber, V (Ed.) editors(s). Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.. p. 223-234.
Rare Clonal Myeloid Diseases
Melchardt T, Weiss L, Pleyer L, Neureiter D, Faber V, Greil R.
In Greil R., Pleyer L., Neureiter D., Faber V. (Editors) , Chronic Myeloid Neoplasias and Clonal Overlap Syndromes. Wien New York: Springer (2010) , Springer, 2010. (ISBN 978-3-211-79891-1)
Chronic Myeloid Neoplasias and Clonal Overlap Syndromes.
Greil, R, Pleyer, L, Neureiter, D, Faber, V,
2010.
Short review – Management of Immune Thrombocytopenia in adults
Lukas Weiss, Richard Greil,
Magazine of European Medical Oncology. 2010, Volume 3, Issue 2: 69-72.
Triple negative breast cancer
Ressler S. Mlineritsch B Greil R
memo - Magazine of European Medical Oncology. 2010, 3: 185-189.
Dose-dense therapy improves survival in aggressive non-Hodgkin's lymphoma.
Fridrik MA, Hausmaninger H, Lang A, Drach J, Krieger O, Geissler D, Michlmayr G, Ulsperger E, Chott A, Oberaigner W, Greil R.
Ann Hematol. 2010 Mar,89(3):273-82. doi: 10.1007/s00277-009-0811-x. Epub 2009 Aug 20.
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PLZF/ZBTB16, a glucocorticoid response gene in acute lymphoblastic leukemia interferes with glucocorticoid-induced apoptosis.
Wasim M, Carlet M, Mansha M, Greil R, Ploner C, Trockenbacher A, Rainer J, Kofler R.
J Steroid Biochem Mol Biol. 2010 Jun,120(4-5):218-27. doi: 10.1016/j.jsbmb.2010.04.019. Epub 2010 May 6.
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Clinical outcome of pretreated B-cell chronic lymphocytic leukemia following alemtuzumab therapy: a retrospective study on various cytogenetic risk categories.
Fiegl M, Erdel M, Tinhofer I, Brychtova Y, Panovska A, Doubek M, Eigenberger K, Fonatsch C, Hopfinger G, MГјhlberger H, Zabernigg A, Falkner F, Gastl G, Mayer J, Greil R
Ann Oncol. 2010 Dec,21(12):2410-9. doi: 10.1093/annonc/mdq236. Epub 2010 May 13.
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Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia.
Saglio G, Kim DW, Issaragrisil S, le Coutre P, Etienne G, Lobo C, Pasquini R, Clark RE, Hochhaus A, Hughes TP, Gallagher N, Hoenekopp A, Dong M, Haque A, Larson RA, Kantarjian HM
N Engl J Med. 2010 Jun 17,362(24):2251-9. doi: 10.1056/NEJMoa0912614. Epub 2010 Jun 5.
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Evidence for the conversion of docetaxel into 7'-epidocetaxel in patients receiving Taxotere-based conventional chemotherapy.
Czejka M, Greil R, Ulsperger E, Schnait H, Kienesberger K, Brumnik T, Farkouh A, Schierholz J.
Int J Clin Pharmacol Ther. 2010 Jul,48(7):483-4.
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Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial.
Eich HT, Diehl V, Görgen H, Pabst T, Markova J, Debus J, Ho A, Dörken B, Rank A, Grosu AL, Wiegel T, Karstens JH, Greil R, Willich N, Schmidberger H, Döhner H, Borchmann P, Müller-Hermelink HK, Müller RP, Engert A.
J Clin Oncol. 2010 Sep 20,28(27):4199-206. doi: 10.1200/JCO.2010.29.8018. Epub 2010 Aug 16.
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Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.
Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Turner SD, Greil R, Kenner L.
Proc Natl Acad Sci U S A. 2010 Sep 14,107(37):16228-33. doi: 10.1073/pnas.1009719107. Epub 2010 Aug 30.
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Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.
Engert A, Plütschow A, Eich HT, Lohri A, Dörken B, Borchmann P, Berger B, Greil R, Willborn KC, Wilhelm M, Debus J, Eble MJ, Sökler M, Ho A, Rank A, Ganser A, Trümper L, Bokemeyer C, Kirchner H, Schubert J, Král Z, Fuchs M, et al.
N Engl J Med. 2010 Aug 12,363(7):640-52. doi: 10.1056/NEJMoa1000067.
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Light chain-induced acute renal failure can be reversed by bortezomib-doxorubicin-dexamethasone in multiple myeloma: results of a phase II study.
Ludwig H, Adam Z, Hajek R, Greil R, TГіthovГЎ E, Keil F, Autzinger EM, Thaler J, Gisslinger H, Lang A, Egyed M, Womastek I, Zojer N.
J Clin Oncol. 2010 Oct 20,28(30):4635-41. doi: 10.1200/JCO.2010.28.1238. Epub 2010 Sep 7.
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Modulation of plasma complement by the initial dose of epirubicin/docetaxel therapy in breast cancer and its predictive value.
Michlmayr A, Bachleitner-Hofmann T, Baumann S, Marchetti-Deschmann M, Rech-Weichselbraun I, Burghuber C, Pluschnig U, Bartsch R, Graf A, Greil R, Allmaier G, Steger G, Gnant M, Bergmann M, Oehler R.
Br J Cancer. 2010 Oct 12,103(8):1201-8. doi: 10.1038/sj.bjc.6605909. Epub 2010 Sep 28.
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Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Correa C, McGale P, Taylor C, Wang Y, Clarke M, Davies C, Peto R, Bijker N, Solin L, Darby S.
J Natl Cancer Inst Monogr. 2010,2010(41):162-77. doi: 10.1093/jncimonographs/lgq039.
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Neue Therapie in Sicht.
Merkel O, Kenner L, Greil R
SpringerMedizin. 22.09.2010
Deletion of Puma and p21(Waf1) In Mice Deactivates p53-Induced Cell Death and Cell Cycle Arrest, but Protects Mice From Irradiation-Induced Lymphomagenesis by a Mechanism Involving Hemopoietic Stem Cell Quiescence
Hofbauer, JP, Holler, C, Denk, U, Asslaber, D, Fastner, G, Labi, V, Villunger, A, Greil, R, Egle, A
BLOOD. 2010, 116(21): 45-46.
Final Analysis of Induction Treatment with Fludarabine, Cyclophosphamide Plus Rituximab (FCR) Followed by Fludarabine Plus Rituximab (FR) and Remission Maintenance Therapy with Rituximab In Previously Untreated B-Chronic Lymphocytic Leukemia (B-CLL): The Chairos AGMT CLL4/Roche ML18434 Study
Egle, A, Weiss, L, Melchardt, T, Gunsilius, E, Petzer, AL, Fridrik, M, Lang, A, Krieger, O, Thaler, J, Greil, R
BLOOD. 2010, 116(21): 593-594.
Enzastaurin kills human CLL cells regardless of clinical risk profile, but fails to prolong life in a murine CLL model
Kocher, T, Pinon, HJ, Holler, C, Denk, U, Greil, R, Egle, A
ONKOLOGIE. 2010, 33: 40-40.
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27,115(21):4191-7. doi: 10.1182/blood-2009-07-234823. Epub 2010 Jan 20.
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Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel O, Asslaber D, PiГ±Гіn JD, Egle A, Greil R.
Cell Cycle. 2010 Jul 15,9(14):2764-8. Epub 2010 Jul 3.
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An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wien Klin Wochenschr. 2010 Dec,122(23-24):717-9. doi: 10.1007/s00508-010-1480-4. Epub 2010 Dec 7.
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MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer.
Asslaber D, Pinon Hofbauer J, Greil R, Egle A.
Journal of Nucleic Acids Investigations. 2010, Dec 1, 1(1): 76-80.
Inhibition of GLI, but not Smoothened induces apoptosis in chronic lymphocytic leukemia cells.
Desch P, Asslaber D, Kern D, Schnidar H, Mangelberger D, Alinger B, Stoecher M, Hofbauer SW, Neureiter D, Tinhofer I, Aberger F, Hartmann TN, Greil R.
Oncogene. 2010 Sep 2,29(35):4885-95. doi: 10.1038/onc.2010.243. Epub 2010 Jul 5.
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Modifying akt signaling in B-cell chronic lymphocytic leukemia cells.
Hofbauer SW, Piñón JD, Brachtl G, Haginger L, Wang W, Jöhrer K, Tinhofer I, Hartmann TN, Greil R.
Cancer Res. 2010 Sep 15,70(18):7336-44. doi: 10.1158/0008-5472.CAN-09-4411. Epub 2010 Sep 7.
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The Nationwide Austrian Aspergillus Registry: a prospective data collection on epidemiology, therapy and outcome of invasive mould infections in immunocompromised and/or immunosuppressed patients.
Perkhofer S, Lass-Flörl C, Hell M, Russ G, Krause R, Hönigl M, Geltner C, Auberger J, Gastl G, Mitterbauer M, Willinger B, Knöbl P, Resch G, Waldner R, Makrai A, Hartmann G, Girschikofsky M, Greil R.
Int J Antimicrob Agents. 2010 Dec,36(6):531-6. doi: 10.1016/j.ijantimicag.2010.08.010. Epub 2010 Oct 13.
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The role of the VLA-4 integrin in adhesion and survival of chronic lymphocytic leukemia (CLL) cells
Sahakyan, K, Hofbauer, S, Brachtl, G, Girbl, T, Henschler, R, Greil, R, Hartmann, TN
ONKOLOGIE. 2010, 33: 201-201.
VLA-4 and CD38 in chronic lymphocytic leukemia - more than prognostic markers?
Brechtl, G, Denk, U, Pinon-Hofbauer, JD, Greil, R, Hartmann, TN
ONKOLOGIE. 2010, 33: 201-202.
2000 - 2009
Final Results of ABCSG-24, a Randomized Phase III Study Comparing Epirubicin, Docetaxel, and Capecitabine (EDC) to Epirubicin and Docetaxel (ED) as Neoadjuvant Treatment for Early Breast Cancer and Comparing ED/EDC plus Trastuzumab (T) to ED/EDC as Neoadjuvant Treatment for Early HER-2 Positive Breast Cancer
Steger, GG, Greil, R, Jakesz, R, Lang, A, Mlineritsch, B, Melbinger-Zeinitzer, E, Marth, C, Samonigg, H, Kubista, E, Gnant, M
CANCER RES. 2009, 69(24): 564S-564S.
Neoadjuvant chemoradiation therapy with capecitabine (X) plus cetuximab (C), and external beam radiotherapy (RT) in locally advanced rectal cancer (LARC): ABCSG trial R03
Eisterer, WM, De Vries, A, Oefner, D, Greil, R, Rabl, H, Tschmelitsch, J, Schmid, R, Kapp, K, Zehentmayr, F, Thaler, J
J CLIN ONCOL. 2009, 27(15):
ADDITION OF ZOLEDRONIC ACID (ZOL) TO ADJUVANT ENDOCRINE THERAPY IMPROVES DISEASE-FREE (DFS) AND RECURRENCE-FREE SURVIVAL (RFS) IN PREMENOPAUSAL WOMEN WITH HORMONE-RESPONSIVE EARLY BREAST CANCER (HREBC): MULTIVARIATE ANALYSES OF THE AUSTRIAN BREAST AND COLORECTAL CANCER STUDY GROUP 12 (ABCSG-12) TRIAL
Gnant, M, Mlineritsch, B, Schippinger, W, Luschin-Ebengreuth, G, Poestlberger, S, Menzel, C, Jakesz, R, Kubista, E, Marth, C, Greil, R
ANN ONCOL. 2009, 20: 30-30.
Number needed to treat (NNT) as a drug efficacy measure: Zoledronic acid (ZOL) for early hormone-responsive breast cancer in the ABCSG-12 trial
Gnant, M, Mlineritsch, B, Schippinger, W, Luschin-Ebengreuth, G, Steger, G, Bjelic-Radisic, V, Jakesz, R, Kubista, E, Marth, C, Greil, R
BREAST. 2009, 18: S59-S59.
The number needed to treat (NNT) as a measure of drug efficacy: the case of zoledronic acid for early hormone-responsive breast cancer in the ABCSG-12 trial
Gnant, M, Mlineritsch, B, Schippinger, W, Luschin-Ebengreuth, G, Steger, G, Bjelic-Radisic, V, Jakesz, R, Kubista, E, Marth, C, Greil, R
CANCER RES. 2009, 69(2): 191S-191S.
Pharmacogenetic (CYP2D6) and gene expression profiles (HOXB13/IL17BR and molecular grade index) for prediction of adjuvant endocrine therapy benefit in the ABCSG 8 trial.
Goetz, M, Ames, M, Gnant, M, Filpits, M, Jakesz, R, Greil, R, Marth, C, Samonigg, H, Suman, V, Safgren, S, Kuffel, M, Weinshilboum, R, Erlander, M, Ma, XJ, Ingle, J
CANCER RES. 2009, 69(2): 77S-77S.
Bevacizumab (Bev) combined with either capecitabine (X) or weekly paclitaxel (Pac) as first-line therapy for HER2-negative locally recurrent or metastatic breast cancer (LR/MBC): the CECOG phase III TURANDOT trial
Lang, I, Inbar, M, Steger, G, Greil, R, Zvirbule, Z, Beslija, S, Kahan, Z, Taskova, V, Kaufmann, B, Zielinski, CC
EJC SUPPL. 2009, 7(2): 277-278.
NUMBER NEEDED TO TREAT (NNT) AS A MEASURE OF ZOLEDRONIC ACID (ZOL) EFFICACY IN PATIENTS WITH HORMONE-RESPONSIVE EARLY BREAST CANCER (BC) IN THE AUSTRIAN BREAST AND COLORECTAL CANCER STUDY GROUP (ABCSG)-12 TRIAL
Gnant, M, Mlineritsch, B, Schippinger, W, Luschin-Ebengreuth, G, Steger, GG, Bjelic-Radisic, V, Jakesz, R, Kubista, E, Marth, C, Greil, R
ANN ONCOL. 2009, 20: 30-30.
A randomized phase III study comparing epirubicin, docetaxel, and capecitabine (EDC) to epirubicin and docetaxel (ED) as neoadjuvant treatment for early breast cancer - first results of the Austrian Breast and Colorectal Cancer Study Group-Trial 24 (ABCSG-24)
Steger, GG, Greil, R, Jakesz, R, Lang, A, Mlineritsch, B, Melbinger-Zeinitzer, E, Martin, C, Samonigg, H, Kubista, E, Gnant, M
EJC SUPPL. 2009, 7(3): 3-3.
REVERSAL OF ACUTE RENAL IMPAIRMENT BY BORTEZOMIB-DOXORUBICIN-DEXAMETHASONE IN MULTIPLE MYELOMA. RESULTS FROM AN PHASE II STUDY
Ludwig, H, Adam, Z, Greil, R, Tothova, E, Keil, F, Zojer, N, Thaler, J, Gisslinger, H, Egyed, M, Lang, A
HAEMATOL-HEMATOL J. 2009, 94: 154-154.
The involvement of the fractalkine receptor in the transmigration of neuroblastoma cells through bone-marrow endothelial cells.
Nevo I, Sagi-Assif O, Meshel T, Ben-Baruch A, Jöhrer K, Greil R, Trejo LE, Kharenko O, Feinmesser M, Yron I, Witz IP.
Cancer Lett. 2009 Jan 8,273(1):127-39. doi: 10.1016/j.canlet.2008.07.029. Epub 2008 Sep 7.
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Hodgkin lymphoma in Tyrol-a population-based study.
Fong D, Steurer M, Greil R, Gunsilius E, Spizzo G, Gastl G, Tzankov A.
Ann Hematol. 2009 May,88(5):449-56. doi: 10.1007/s00277-008-0618-1. Epub 2008 Oct 10.
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Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma.
Ludwig H, Hajek R, TГіthovГЎ E, Drach J, Adam Z, Labar B, Egyed M, Spicka I, Gisslinger H, Greil R, Kuhn I, Zojer N, Hinke A.
Blood. 2009 Apr 9,113(15):3435-42. doi: 10.1182/blood-2008-07-169565. Epub 2008 Oct 27.
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Multicenter phase II study of pegylated liposomal doxorubicin in combination with vinorelbine as first-line treatment in elderly patients with metastatic breast cancer.
Mlineritsch B, Schabel-Moser R, Andel J, Fridrik M, Moik M, Mayer P, Russ G, Rass C, Greil R
Onkologie. 2009 Feb,32(1-2):18-24. doi: 10.1159/000180915. Epub 2009 Jan 20.
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Endocrine therapy plus zoledronic acid in premenopausal breast cancer.
Gnant M, Mlineritsch B, Schippinger W, Luschin-Ebengreuth G, Pöstlberger S, Menzel C, Jakesz R, Seifert M, Hubalek M, Bjelic-Radisic V, Samonigg H, Tausch C, Eidtmann H, Steger G, Kwasny W, Dubsky P, Fridrik M, Fitzal F, Stierer M, Rücklinger E, Greil R
N Engl J Med. 2009 Feb 12,360(7):679-91. doi: 10.1056/NEJMoa0806285. Erratum in: N Engl J Med. 2009 May 28,360(22):2379.
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Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer.
Lin NU, DiГ©ras V, Paul D, Lossignol D, Christodoulou C, Stemmler HJ, RochГ© H, Liu MC, Greil R, Ciruelos E, Loibl S, Gori S, Wardley A, Yardley D, Brufsky A, Blum JL, Rubin SD, Dharan B, Steplewski K, Zembryki D, Oliva C, Roychowdhury D, et al.
Clin Cancer Res. 2009 Feb 15,15(4):1452-9. doi: 10.1158/1078-0432.CCR-08-1080.
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Difference in the relative distribution of CD4+ T-cell subsets in B-CLL with mutated and unmutated immunoglobulin (Ig) VH genes: implication for the course of disease.
Tinhofer I, Weiss L, Gassner F, Rubenzer G, Holler C, Greil R.
J Immunother. 2009 Apr,32(3):302-9. doi: 10.1097/CJI.0b013e318197b5e4.
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Neoadjuvant bevacizumab, docetaxel and capecitabine combination therapy for HER2/neu-negative invasive breast cancer: Efficacy and safety in a phase II pilot study.
Greil R, Moik M, Reitsamer R, Ressler S, Stoll M, Namberger K, Menzel C, Mlineritsch B.
Eur J Surg Oncol. 2009 Oct,35(10):1048-54. doi: 10.1016/j.ejso.2009.01.014. Epub 2009 Feb 27.
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Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer.
Baselga J, Semiglazov V, van Dam P, Manikhas A, Bellet M, Mayordomo J, Campone M, Kubista E, Greil R, Bianchi G, Steinseifer J, Molloy B, Tokaji E, Gardner H, Phillips P, Stumm M, Lane HA, Dixon JM, Jonat W, Rugo HS.
J Clin Oncol. 2009 Jun 1,27(16):2630-7. doi: 10.1200/JCO.2008.18.8391. Epub 2009 Apr 20.
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Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3.
Van Cutsem E, Labianca R, Bodoky G, Barone C, Aranda E, Nordlinger B, Topham C, Tabernero J, AndrГ© T, Sobrero AF, Mini E, Greil R, Di Costanzo F, Collette L, Cisar L, Zhang X, Khayat D, Bokemeyer C, Roth AD, Cunningham D.
J Clin Oncol. 2009 Jul 1,27(19):3117-25. doi: 10.1200/JCO.2008.21.6663. Epub 2009 May 18.
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Maintaining bone density in patients undergoing treatment for breast cancer: is there an adjuvant benefit?
Gnant M, Dubsky P, Fitzal F, Blaha P, Schoppmann S, Steger G, Marth C, Samonigg H, HГјttner K, Fohler H, Ruecklinger E, Jakesz R, Greil R
Clin Breast Cancer. 2009 Jun,9 Suppl 1:S18-27. doi: 10.3816/CBC.2009.s.002. Review.
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Low p27 expression predicts early relapse and death in postmenopausal hormone receptor-positive breast cancer patients receiving adjuvant tamoxifen therapy.
Filipits M, Rudas M, Heinzl H, Jakesz R, Kubista E, Lax S, Schippinger W, Dietze O, Greil R, Stiglbauer W, Kwasny W, Nader A, Stierer M, Gnant MF
Clin Cancer Res. 2009 Sep 15,15(18):5888-94. doi: 10.1158/1078-0432.CCR-09-0728. Epub 2009 Sep 1.
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Vincristine, idarubicin dexamethasone and thalidomide in scleromyxoedema.
Laimer M, Namberger K, Massone C, Koller J, Emberger M, Pleyer L, Hintner H, Greil R.
Acta Derm Venereol. 2009 Nov,89(6):631-5. doi: 10.2340/00015555-0731.
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The Dark Side of the Moon - the Side Effects of Therapy in a Dynamic Era of Breast Cancer Management.
Greil R.
Breast Care (Basel). 2009,4(3):144-147. Epub 2009 Jun 26.
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FINAL RESULTS OF ORAL FLUDARABINE WITH CONCOMITANT SUBCUTANEOUS ALEMTUZUMAB IN RELAPSED/REFRACTORY B-CHRONIC LYMPHOCYTIC LEUKAEMIA (B-CLL): THE FLUSALEM STUDY
Egle, A, Melchardt, T, Pleyer, L, Tinhofer, I, Lang, A, Keil, F, Thaler, J, Gunsilius, E, Fridrik, M, Greil, R
HAEMATOL-HEMATOL J. 2009, 94: 140-140.
The Inverse Correlation of Regulatory T Cells and Time to Initial Treatment in Chronic Lymphocytic B-Cell Leukemia
Weiss, L, Melchardt, T, Grabmer, C, Egle, A, Tinhofer, I, Greil, R
BLOOD. 2009, 114(22): 510-510.
The REVLIRIT CLL5 AGMT Study - a Phase I/II Trial Combining Fludarabine/Rituximab with Escalating Doses of Lenalidomide Followed by Rituximab/Lenalidomide in Untreated Chronic Lymphocytic Leukemia (CLL): Results of a Planned Interim Analysis
Egle, A, Steurer, M, Melchardt, T, Stoll, M, Greil, R
BLOOD. 2009, 114(22): 1341-1342.
PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.
Holler C, PiГ±Гіn JD, Denk U, Heyder C, Hofbauer S, Greil R, Egle A.
Blood. 2009 Mar 19,113(12):2791-4. doi: 10.1182/blood-2008-06-160713. Epub 2009 Jan 23.
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Initial evaluation of the Roche COBAS TaqMan HIV-1 v2.0 assay for determining viral load in HIV-infected individuals.
Taylor N, Schmid I, Egle A, Greil R, Patsch W, Oberkofler H.
Antivir Ther. 2009,14(8):1189-93. doi: 10.3851/IMP1427.
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Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymph nodes and bone marrow.
Hartmann TN, Grabovsky V, Wang W, Desch P, Rubenzer G, Wollner S, Binsky I, Vallon-Eberhard A, Sapoznikov A, Burger M, Shachar I, Haran M, Honczarenko M, Greil R, Alon R.
Cancer Res. 2009 Apr 1,69(7):3121-30. doi: 10.1158/0008-5472.CAN-08-4136. Epub 2009 Mar 17.
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Molecular and cellular mechanisms of CLL: novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nat Rev Clin Oncol. 2009 Jul,6(7):405-18. doi: 10.1038/nrclinonc.2009.72. Epub 2009 Jun 2.
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Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discov Med. 2009 Oct,8(42):157-64.
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Bim and Bmf in tissue homeostasis and malignant disease.
PiГ±on JD, Labi V, Egle A, Villunger A.
Oncogene. 2008 Dec,27 Suppl 1:S41-52. doi: 10.1038/onc.2009.42.
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A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells.
Hartmann TN, Grabovsky V, Pasvolsky R, Shulman Z, Buss EC, Spiegel A, Nagler A, Lapidot T, Thelen M, Alon R.
J Leukoc Biol. 2008 Oct,84(4):1130-40. doi: 10.1189/jlb.0208088. Epub 2008 Jul 24.
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IMMUNOMODULATORY CAPACITY OF MYELOMA-DERIVED CHEMOKINE CCL27
Johrer, K, Olivier, A, Unger, M, Maizner, E, Neureiter, D, Greil, R
ANTICANCER RES. 2008, 28(5C): 3336-3337.
R-CHOP plus thalidomide for previously untreated mantle cell lymphoma
Drach, J, Hopfinger, G, Fridrik, M, Greil, R, Thaler, J, Keil, F, Lang, A, Jaeger, U, Raderer, M
ANN ONCOL. 2008, 19: 214-215.
Adjuvant ovarian suppression combined with tamoxifen or anastrozole, alone or in combination with zoledronic acid, in premenopausal women with hormone-responsive, stage I and II breast cancer: First efficacy results from ABCSG-12
Gnant, M, Mlineritsch, B, Schippinger, W, Luschin-Ebengreuth, G, Poestlberger, S, Menzel, C, Jakesz, R, Kubista, E, Marth, C, Greil, R
J CLIN ONCOL. 2008, 26(15):
The Austrian Fulvestrant Registry: Results from a prospective observation of fulvestrant in postmenopausal patients
Bartsch, R, Mlineritsch, B, Gnant, M, Niernberger, T, Pluschnig, U, Greil, R, Pober, M, Sevelda, P, Thaler, J, Steger, GG
J CLIN ONCOL. 2008, 26(15):
The single nucleotide polymorphism MDM2-SNP309 influences sensitivity of B-CLL cells to the non-genotoxic activator of the p53 pathway Nutlin-3a
Tinhofer, I, Seyfried, I, Stoecher, M, Hofbauer, S, Daniel, PT, Greil, R
J CLIN ONCOL. 2008, 26(15):
Twelve-year retrospective analysis of lung cancer-The TYROL Study: Daily routine in 1,424 patients (1995-2006)
Fiegl, M, Hilbe, W, Auberger, J, Schmid, T, Auberger, T, Tzankov, A, Sterlacci, W, Denz, H, Jamnig, H, Greil, R
J CLIN ONCOL. 2008, 26(15):
R-CHOP plus THALIDOMIDE FOR PREVIOUSLY UNTREATED MANTLE CELL LYMPHOMA
Drach, W, Hopfinger, G, Fridrik, M, Greil, R, Thaler, J, Keil, F, Lang, A, Jaeger, U, Raderer, M
HAEMATOL-HEMATOL J. 2008, 93: 394-395.
MULTIPLE MYELOMA - CHEMOKINE NETWORK: CCL27/CTACK - A NEW PLAYER IN MYELOMA PROGRESSION
Olivier, A, Unger, M, Maizner, E, Neureiter, D, Greil, R, Johrer, K
ANTICANCER RES. 2008, 28(5C): 3429-3429.
ZOLEDRONIC ACID (ZOL) IMPROVES DISEASE-FREE (DFS) AND RECURRENCE-FREE SURVIVAL (RFS) IN PREMENOPAUSAL WOMEN WITH EARLY BREAST CANCER (ERBC) RECEIVING ADJUVANT ENDOCRINE THERAPY: MULTIVARIATE ANALYSIS OF EFFICACY DATA FROM THE AUSTRIAN BREAST AND COLORECTAL CANCER STUDY GROUP (ABCSG)-12
Gnant, M, Mlineritsch, B, Schippinger, W, Luschin-Ebengreuth, G, Steger, GG, Bjelic-Radisic, V, Jakesz, R, Kubista, E, Marth, C, Greil, R
ANN ONCOL. 2008, 19: 44-44.
Diagnostic algorithms, monitoring, prognostication, and therapy in chronic myeloid leukemia (CML): a proposal of the Austrian CML platform
Valent, P, Lion, T, Wolf, D, Sillaber, C, Agis, H, Petzer, A, Lang, A, Kalhs, P, Geissler, D, Greil, R, Linkesch, W, Burgstaller, S, Thaler, J, Gastl, G
WIEN KLIN WOCHENSCHR. 2008, 120(21-22): 697-709.
The potential risk of neoadjuvant chemotherapy in breast cancer patients--results from a prospective randomized trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-07).
Taucher S, Steger GG, Jakesz R, Tausch C, Wette V, Schippinger W, Kwasny W, Reiner G, Greil R, Dubsky P, Poestlberger S, Tschmelitsch J, Samonigg H, Gnant M
Breast Cancer Res Treat. 2008 Nov,112(2):309-16. Epub 2007 Dec 14.
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Exemestane as primary systemic treatment for hormone receptor positive post-menopausal breast cancer patients: a phase II trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-17).
Mlineritsch B, Tausch C, Singer C, Luschin-Ebengreuth G, Jakesz R, Ploner F, Stierer M, Melbinger E, Menzel C, Urbania A, Fridrik M, Steger G, Wohlmuth P, Gnant M, Greil R
Breast Cancer Res Treat. 2008 Nov,112(1):203-13. Epub 2007 Dec 22.
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A phase I/II study of bortezomib and capecitabine in patients with metastatic breast cancer previously treated with taxanes and/or anthracyclines.
Schmid P, KГјhnhardt D, Kiewe P, Lehenbauer-Dehm S, Schippinger W, Greil R, Lange W, Preiss J, Niederle N, Brossart P, Freier W, KГјmmel S, Van de Velde H, Regierer A, Possinger K.
Ann Oncol. 2008 May,19(5):871-6. doi: 10.1093/annonc/mdm569. Epub 2008 Jan 21.
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Oxaliplatin in combination with 5-fluorouracil/leucovorin or capecitabine in elderly patients with metastatic colorectal cancer.
Arkenau HT, Graeven U, Kubicka S, Grothey A, Englisch-Fritz C, Kretzschmar A, Greil R, Freier W, Seufferlein T, Hinke A, Schmoll HJ, Schmiegel W, Porschen R
Clin Colorectal Cancer. 2008 Jan,7(1):60-4.
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Tumour-immune cell interactions modulated by chemokines.
Jöhrer K, Pleyer L, Olivier A, Maizner E, Zelle-Rieser C, Greil R.
Expert Opin Biol Ther. 2008 Mar,8(3):269-90. doi: 10.1517/14712598.8.3.269 .
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Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13.
Merkel O, Heyder C, Asslaber D, Hamacher F, Tinhofer I, Holler C, Stöcher M, Prokesch A, Papak C, Scheideler M, Trajanoski Z, Greil R.
J Mol Med (Berl). 2008 May,86(5):541-52. doi: 10.1007/s00109-008-0314-6. Epub 2008 Feb 23.
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Combined pegylated liposomal doxorubicin and bortezomib is highly effective in patients with recurrent or refractory multiple myeloma who received prior thalidomide/lenalidomide therapy.
Sonneveld P, Hajek R, Nagler A, Spencer A, BladГ© J, Robak T, Zhuang SH, Harousseau JL, Orlowski RZ
Cancer. 2008 Apr 1,112(7):1529-37. doi: 10.1002/cncr.23326.
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Renal safety profiles of ibandronate 6 mg infused over 15 and 60 min: a randomized, open-label study.
von Moos R, Caspar CB, ThГјrlimann B, Angst R, Inauen R, Greil R, Bergstrom B, Schmieding K, Pecherstorfer M.
Ann Oncol. 2008 Jul,19(7):1266-70. doi: 10.1093/annonc/mdn038. Epub 2008 Mar 11.
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Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy.
Rudas M, Lehnert M, Huynh A, Jakesz R, Singer C, Lax S, Schippinger W, Dietze O, Greil R, Stiglbauer W, Kwasny W, Grill R, Stierer M, Gnant MF, Filipits M
Clin Cancer Res. 2008 Mar 15,14(6):1767-74. doi: 10.1158/1078-0432.CCR-07-4122.
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Anemia is a significant prognostic factor in local relapse-free survival of premenopausal primary breast cancer patients receiving adjuvant cyclophosphamide/methotrexate/5-fluorouracil chemotherapy.
Dubsky P, Sevelda P, Jakesz R, Hausmaninger H, Samonigg H, Seifert M, Denison U, Mlineritsch B, Steger G, Kwasny W, Stöger H, Bartsch R, Stierer M, Taucher S, Fridrik M, Schippinger W, Greil R, Pötter R, Gnant M
Clin Cancer Res. 2008 Apr 1,14(7):2082-7. doi: 10.1158/1078-0432.CCR-07-2068.
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Erythropoietins in cancer patients: ESMO recommendations for use.
Greil R, Thödtman R, Roila F
Ann Oncol. 2008 May,19 Suppl 2:ii113-5. doi: 10.1093/annonc/mdn106.
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Hematopoietic growth factors: ESMO recommendations for the applications.
Greil R, Psenak O, Roila F
Ann Oncol. 2008 May,19 Suppl 2:ii116-8. doi: 10.1093/annonc/mdn107.
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MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia.
Gryshchenko I, Hofbauer S, Stoecher M, Daniel PT, Steurer M, Gaiger A, Eigenberger K, Greil R, Tinhofer I.
J Clin Oncol. 2008 May 10,26(14):2252-7. doi: 10.1200/JCO.2007.11.5212.
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Chemotherapy in gastric cancer.
Wöll E, Devries A, Eisterer W, Hejna M, Keil F, Stein H, Zacherl J, Greil R.
Anticancer Res. 2008 Mar-Apr,28(2B):1213-9.
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The Austrian fulvestrant registry: results from a prospective observation of fulvestrant in postmenopausal patients with metastatic breast cancer.
Bartsch R, Mlineritsch B, Gnant M, Niernberger T, Pluschnig U, Greil R, Wenzel C, Sevelda P, Thaler J, Rudas M, Pober M, Zielinski CC, Steger GG
Breast Cancer Res Treat. 2009 May,115(2):373-80. doi: 10.1007/s10549-008-0132-0. Epub 2008 Jul 26.
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Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy.
Gnant M, Mlineritsch B, Luschin-Ebengreuth G, Kainberger F, Kässmann H, Piswanger-Sölkner JC, Seifert M, Ploner F, Menzel C, Dubsky P, Fitzal F, Bjelic-Radisic V, Steger G, Greil R, Marth C, Kubista E, Samonigg H, Wohlmuth P, Mittlböck M, Jakesz R
Lancet Oncol. 2008 Sep,9(9):840-9. doi: 10.1016/S1470-2045(08)70204-3. Epub 2008 Aug 19.
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SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a.
Seyfried I, Hofbauer S, Stoecher M, Greil R, Tinhofer I.
Blood. 2008 Sep 1,112(5):2168, author reply 2169. doi: 10.1182/blood-2008-05-158634.
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Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma.
San Miguel JF, Schlag R, Khuageva NK, Dimopoulos MA, Shpilberg O, Kropff M, Spicka I, Petrucci MT, Palumbo A, Samoilova OS, Dmoszynska A, Abdulkadyrov KM, Schots R, Jiang B, Mateos MV, Anderson KC, Esseltine DL, Liu K, Cakana A, van de Velde H, Richardson PG
N Engl J Med. 2008 Aug 28,359(9):906-17. doi: 10.1056/NEJMoa0801479.
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Biweekly oxaliplatin and irinotecan chemotherapy in advanced gastric cancer. A first-line multicenter phase II trial of the Arbeitsgemeinschaft Medikamentöse Tumortherapie (AGMT).
Wöll E, Kühr T, Eisterer W, Gattringer K, Greil R, Zabernigg A, Hilbe W, Thaler J.
Anticancer Res. 2008 Sep-Oct,28(5B):2901-5.
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Diagnostic algorithms, monitoring prognostication and therapy in chronic myeloid leukemia (CML): a proposal of the Austrian CML platform.
Valent P, Lion T, Wolf D, Sillaber C, Agis H, Petzer A, Lang A, Kalhs P, Geissler D, Greil R, Linkesch W, Burgstaller S, Thaler J, Gastl G.
Wien Klin Wochenschr. 2008,120(21-22):697-709. doi: 10.1007/s00508-008-1100-8.
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Differential diagnostic challenge of chronic neutrophilic leukemia in a patient with prolonged leukocytosis.
Neureiter D, Kemmerling R, Ocker M, Seidlhofer C, Faber V, Stöcher M, Greil R, Dietze O.
J Hematop. 2008 Jul,1(1):23-7. doi: 10.1007/s12308-008-0004-x. Epub 2008 Apr 19.
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Is Chemoendocrine Treatment without Alternative?
Greil R.
Breast Care (Basel). 2008,3(4):231-235. Epub 2008 Aug 22.
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T Cell Dynamics during the Pretumor and Tumor Phase in the Murine Tcll Transgenic Chronic Lymphocytic Leukemia Model
Egle, A, Pinon, JD, Heyder, C, Holler, C, Denk, U, Tinhofer, I, Greil, R
BLOOD. 2008, 112(11): 1078-1078.
Minimal Residual Disease (MRD) and T/NK Cell Dynamics during Fludarabine, Cyclophosphamide Plus Rituximab (FCR) Followed by Fludarabine Plus Rituximab (FR) and Remission Maintenance Therapy with Rituximab in Previously Untreated B-Chronic Lymphocytic Leukemia (B-CLL): Riskfactor Stratification in the Chairos Study.
Egle, A, Weiss, L, Gassner, F, Russ, G, Pleyer, L, Gunsilius, E, Tinhofer, I, Thaler, J, Petzer, AL, Greil, R
BLOOD. 2008, 112(11): 1089-1089.
Mitochondrial phosphate-carrier deficiency: a novel disorder of oxidative phosphorylation.
Mayr JA, Merkel O, Kohlwein SD, Gebhardt BR, Böhles H, Fötschl U, Koch J, Jaksch M, Lochmüller H, Horvath R, Freisinger P, Sperl W.
American Journal of Human Genetics. 2007 Mar,80(3):478-84. Epub 2007 Jan 10.
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Zell- und Molekularbiologie.
Tinhofer I.
in Lymphoproliferative Erkrankungen R.Greil Uni-Med Science, Seite 29 - 41
Incidence and other aspects of myelodysplastic syndrome in the Austrian federal state Salzburg
Kemmerling, R, Neuretter, D, Faber, V, Stocher, M, Greil, R, Dietze, O
PATHOL RES PRACT. 2007, 203(5): 392-392.
MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukaemia but can be preferentially targeted by the MDM2 inhibitor Nutlin-3a
Tinhofer, I, Gryshchenko, I, Stoecher, M, Hofbauer, S, Daniel, PT, Greil, R
EJC SUPPL. 2007, 5(4): 347-347.
Therapy of antibody-mediated factor VIII deficiency by immunosuppressive therapy containing cyclophosphamide, dexamethasone and rituximab: A case report
Thoedtmann, R, Rosenlechner, S, Unger, J, Patsch, W, Greil, R
HAEMATOL-HEMATOL J. 2007, 92: 546-546.
Morbus Hodgkin.
Greil, R,
In: Greil, R (Ed.) editors(s). Lymphoproliferative Erkrankungen..
Regulation of apoptosis.
Pleyer, L, Tinhofer, I, Greil, R,
In: Hakan Mellstedt DSDBRG (Ed.) editors(s). ESMO Handbook of principles of translational Research.. p. 67-69.
Entwicklungen und Perspektiven in der Behandlung der Lymphatischen Neoplasien.
Pleyer, L, Desch, P, Greil, R,
In: Greil, R (Ed.) editors(s). Lymphoproliferative Erkrankungen.. p. 139-155.
A new sesquiterpene lactone sulfate from Reichardia gaditana (Asteraceae)
Zidorn, C, Ellmerer, EP, Heller, W, Johrer, K, Frommberger, M, Greil, R, Guggenberger, M, Ongania, KH, Stuppner, H
Z NATURFORSCH B. 2007, 62(1): 132-134.
The Role of Imaging in Malignant Lymphoma: A Critical View on PET Scanning in Current Clinical Practice
Namberger, K, Greil, R,
Imaging decisions (Berlin, Germany). 2007, 10(4): 22-31.
Fulvestrant ('Faslodex') in heavily pretreated postmenopausal patients with advanced breast cancer: single centre clinical experience from the compassionate use programme.
Mlineritsch B, Psenak O, Mayer P, Moik M, Namberger K, Hauser-Kronberger C, Greil R.
Breast Cancer Res Treat. 2007 Nov,106(1):105-12. Epub 2007 Feb 13.
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Is it time to consider neoadjuvant treatment as the standard of care in oesophageal cancer?
Greil R, Stein HJ.
Lancet Oncol. 2007 Mar,8(3):189-90.
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Erythropoietins in cancer patients: ESMO recommendations for use.
ESMO Guidelines Working Group, Greil R, Thödtmann R.
Ann Oncol. 2007 Apr,18 Suppl 2:ii86-8.
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Hematopoietic growth factors: ESMO recommendations for the application.
ESMO Guidelines Working Group, Greil R, Psenak O.
Ann Oncol. 2007 Apr,18 Suppl 2:ii89-91.
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Massive infiltration of bone marrow in colon carcinoma after treatment with activated protein C.
Pleyer L, Went P, Russ G, Prinz E, Faber V, Röwert HJ, Karlbauer R, Greil R.
Wien Klin Wochenschr. 2007,119(7-8):254-8.
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[Expert recommendations 2006 on the rationale for second-line therapy for non-small cell bronchial neoplasms].
Hilbe W, Aigner K, Dittrich C, Eckmayr J, Fiegl M, Flicker M, Forstner B, Greil R, Jamnig H, Krajnik G, Lang A, Mohn-Staudner A, Schinko H, Studnicka M, Pirker R, Ploner F, Rothmund J, Schiller L, Zabernigg A, Zöchbauer-Müller S.
Wien Klin Wochenschr. 2007,119(7-8):259-66.
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Pathologic complete response with six compared with three cycles of neoadjuvant epirubicin plus docetaxel and granulocyte colony-stimulating factor in operable breast cancer: results of ABCSG-14.
Steger GG, Galid A, Gnant M, Mlineritsch B, Lang A, Tausch C, Rudas M, Greil R, Wenzel C, Singer CF, Haid A, Pöstlberger S, Samonigg H, Luschin-Ebengreuth G, Kwasny W, Klug E, Kubista E, Menzel C, Jakesz R
J Clin Oncol. 2007 May 20,25(15):2012-8.
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Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: a final report of the AIO Colorectal Study Group.
Porschen R, Arkenau HT, Kubicka S, Greil R, Seufferlein T, Freier W, Kretzschmar A, Graeven U, Grothey A, Hinke A, Schmiegel W, Schmoll HJ
J Clin Oncol. 2007 Sep 20,25(27):4217-23. Epub 2007 Jun 4.
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A prospective randomised phase III trial of adjuvant chemotherapy with 5-fluorouracil and leucovorin in patients with stage II colon cancer.
Schippinger W, Samonigg H, Schaberl-Moser R, Greil R, Thödtmann R, Tschmelitsch J, Jagoditsch M, Steger GG, Jakesz R, Herbst F, Hofbauer F, Rabl H, Wohlmuth P, Gnant M, Thaler J
Br J Cancer. 2007 Oct 22,97(8):1021-7. Epub 2007 Sep 25.
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Extended adjuvant therapy with anastrozole among postmenopausal breast cancer patients: results from the randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a.
Jakesz R, Greil R, Gnant M, Schmid M, Kwasny W, Kubista E, Mlineritsch B, Tausch C, Stierer M, Hofbauer F, Renner K, Dadak C, RГјcklinger E, Samonigg H
J Natl Cancer Inst. 2007 Dec 19,99(24):1845-53. Epub 2007 Dec 11. Erratum in: J Natl Cancer Inst. 2008 Feb 6,100(3):226.
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Planned first efficacy and safety analysis of de-intensified induction with fludarabine, cyclophosphamide plus rituximab (FCR) followed by fludarabine plus rituximab (FR) and remission maintenance therapy with rituximab in previously untreated B-chronic lymphocytic leukemia (B-CLL): The chairos study
Egle, A, Weiss, L, Russ, G, Thoedtmann, R, Pleyer, L, Gastl, G, Thaler, J, Petzer, A, Tinhofer, I, Greil, R
BLOOD. 2007, 110(11): 609A-609A.
Systemic application of granulocyte-colony stimulating factor and stem cell factor exacerbates excitotoxic brain injury in newborn mice.
Keller M, Simbruner G, Gorna A, Urbanek M, Tinhofer I, Griesmaier E, Sarkozy G, Schwendimann L, Gressens P.
Pediatric Research. 2006 Apr, 59 (4 Pt 1): 549-53.
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Wie sterben wir? Wie schön ist der Tod? Wie teuer ist der Tod? - Die Palliativmedizin im Spannungsfeld der Ressourcenallokation
Greil, R,
In: Fischer, M, Zänker, KS, editors(s). Medizin- und Bioethik. (ISBN: 978-3-631-54744-1 )
Lymphoproliferative Erkrankungen.
Greil, R,
2006.
A role of TRAIL in killing osteoblasts by myeloma cells
Tinhofer, I, Biedermann, R, Krismer, M, Crazzolara, R, Greil, R
FASEB J. 2006 Apr,20(6):759-61. Epub 2006 Jan 25.
The still long and winding road to neoadjuvant sytemic therapy as the standard of care in breast cancer
Greil, R
BREAST CARE. 2006, 1(6): 352-357.
Clinical practice aromatase inhibitors: Upfront, switch or extended?
Greil, R, Jonat, W, Maass, N, Kaufmann, M, Ortmann, O, Possinger, K, Steger, G
BREAST CARE. 2006, 1(1): 37-43.
Adjuvant treatment with trastuzumab in clinical practice outside clinical studies
Senn, HJ, Thurlimann, B, von Minckwitz, G, Herrmann, R, Jakesz, R, Gnant, M, Greil, R
BREAST CARE. 2006, 1(2): 96-101.
A role of TRAIL in killing osteoblasts by myeloma cells.
Tinhofer I, Biedermann R, Krismer M, Crazzolara R, Greil R.
FASEB J. 2006 Apr,20(6):759-61. Epub 2006 Jan 25.
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Diffuse large B-cell lymphoma as a second, clonally unrelated lymphoproliferative disease in a patient with IgM monoclonal gammopathy of undetermined significance (MGUS) and concomitant polycythemia vera rubra.
Mian M, Psenak O, Greil R, Fiegl M, Tzankov A.
Leuk Lymphoma. 2006 May,47(5):940-3. No abstract available.
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Single-agent purine analogues for the treatment of chronic lymphocytic leukaemia: a systematic review and meta-analysis.
Steurer M, Pall G, Richards S, Schwarzer G, Bohlius J, Greil R
Cancer Treat Rev. 2006 Aug,32(5):377-89. Epub 2006 Jun 21. Review.
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IL-4 inhibits the TNF-alpha induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-alpha to induce apoptotic and cytokine responses by RCC: implications for antitumor immune responses.
Falkensammer C, Jöhrer K, Gander H, Ramoner R, Putz T, Rahm A, Greil R, Bartsch G, Thurnher M.
Cancer Immunol Immunother. 2006 Oct,55(10):1228-37. Epub 2006 Jan 28.
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Purine antagonists for chronic lymphocytic leukaemia.
Steurer M, Pall G, Richards S, Schwarzer G, Bohlius J, Greil R.
Cochrane Database Syst Rev. 2006 Jul 19,(3):CD004270.
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Extensive organizing pneumonia during chemo-immunotherapy containing rituximab and G-CSF in a patient with diffuse large B-cell lymphoma: case report and review of the literature.
Mian M, Rass C, Hutarew G, Kofler B, Fiegl M, Greil R.
Leuk Lymphoma. 2006 Aug,47(8):1683-5.
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Routine clinical use of alemtuzumab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: a nation-wide retrospective study in Austria.
Fiegl M, Falkner A, Hopfinger G, Brugger S, Zabernigg A, Bauer F, Haslbauer F, Demirtas D, Grossschmidt P, Tatzreiter G, Gastl G, Greil R
Cancer. 2006 Nov 15,107(10):2408-16.
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Planned first safety and efficacy analysis of oral fludarabine combined with subcutaneous alemtuzumab in 2(nd) line therapy of B-chronic lymphocytic leukaemia (B-CLL): The FLUSALEM study.
Egle, A, Tinhofer, I, Russ, G, Rass, C, Greil, R
BLOOD. 2006, 108(11): 336B-336B.
Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.
Tinhofer I, Rubenzer G, Holler C, Hofstaetter E, Stoecher M, Egle A, Steurer M, Greil R.
Blood. 2006 Nov 1,108(9):2950-6. Epub 2006 Jul 6.
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The effect of IgVH mutational status on the induction of apoptosis by rituximab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: evidence from a clinical phase I/II trial.
Tinhofer I, Steurer M, Leitinger G, Rumpold H, Egle A, Erdel M, Greil R.
Haematologica. 2006 Sep,91(9):1291-3.
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PKC delta is involved in signal attenuation in CD3+ T cells.
Gruber T, Barsig J, Pfeifhofer C, Ghaffari-Tabrizi N, Tinhofer I, Leitges M, Baier G.
Immunology Letters. 2005 Jan 31,96(2): 291-3.
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Alemtuzumab is effective in patients with advanced, pretreated B-cell chronic lymphocytic leukemia: A nationwide study of routine use in Austria
Fiegl, M, Falkner, A, Hopfinger, G, Brugger, S, Zabernigg, A, Haslbauer, F, Andel, J, Thaler, J, Fridrik, M, Bauer, F, Mian, M, Tatzreiter, G, Zoier, N, Demirtas, D, Postner, G, Auberger, J, Gastl, G, Greil, R
BLOOD. 2005, 106(11): 833A-833A.
Purine antagonists for chronic lymphocytic leukemia: Results of a comprehensive meta-analysis
Steurer, M, Pall, G, Richards, S, Schwarzer, G, Bohlius, J, Greil, R
ANN ONCOL. 2005, 16: 203-204.
Chemotherapie im Alter
Greil, R, Faber, V,
In: Likar, R, Bernatzky, G, Pipam, W, Janig, H, Sadjak, A, editors(s). Lebensqualität im Alter. Springer, p. 57-264. (ISBN: 978-3-211-21197-7)
ESMO Minimum Clinical Recommendations for the diagnosis, treatment and follow-up of acute myeloblastic leukemia (AML) in adult patients
Fey, MF, Greil, R, Jost, LM
Ann Oncol. 2005,16 Suppl 1:i48-9.
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Long-term results of dose density therapy in patients with aggressive lymphoma.
Fridrik MA, Hausmaninger H, Linkesch W, Greil R, Krieger O, Baldinger C, Klocker J, Pont J, Oberaigner W.
Ann Hematol. 2005 Apr,84(4):217-22. Epub 2004 Nov 6.
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Polyacetylenes from the Apiaceae vegetables carrot, celery fennel parsley and parsnip and their cytotoxic activities.
Zidorn C, Jöhrer K, Ganzera M, Schubert B, Sigmund EM, Mader J, Greil R, Ellmerer EP, Stuppner H.
J Agric Food Chem. 2005 Apr 6,53(7):2518-23.
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Up-regulation of functional chemokine receptor CCR3 in human renal cell carcinoma.
Jöhrer K, Zelle-Rieser C, Perathoner A, Moser P, Hager M, Ramoner R, Gander H, Höltl L, Bartsch G, Greil R, Thurnher M.
Clin Cancer Res. 2005 Apr 1,11(7):2459-65.
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ESMO Minimum Clinical Recommendations for diagnosis, treatment and follow-up of multiple myeloma.
Harrouseau JL, Greil R, Kloke O
Ann Oncol. 2005,16 Suppl 1:i48-9. No abstract available.
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ESMO Minimum Clinical Recommendations for the diagnosis, treatment and follow-up of acute myeloblastic leukemia (AML) in adult patients.
Fey MF, Greil R, Jost LM
Ann Oncol. 2005,16 Suppl 1:i48-9. No abstract available.
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ESMO Minimum Clinical Recommendations for diagnosis, treatment and follow-up of chronic lymphocytic leukemia.
Hallek M, Stahel RA, Greil R
Ann Oncol. 2005,16 Suppl 1:i50-1. No abstract available.
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ESMO recommendations for the application of hematopoietic growth factors.
Greil R, Jost LM
Ann Oncol. 2005,16 Suppl 1:i80-2. No abstract available.
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Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial.
Jakesz R, Jonat W, Gnant M, Mittlboeck M, Greil R, Tausch C, Hilfrich J, Kwasny W, Menzel C, Samonigg H, Seifert M, Gademann G, Kaufmann M, Wolfgang J
Lancet. 2005 Aug 6-12,366(9484):455-62.
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Continuous prednisolone versus conventional prednisolone with VMCP-interferon-alpha2b as first-line chemotherapy in elderly patients with multiple myeloma.
Ludwig H, Spicka I, Klener P, Greil R, Adam Z, Gisslinger H, TarkovГЎcs G, Linkesch W, Maniatis A, Morant R, Drach J, Kuhn I, Schuster J, Hinke A.
Br J Haematol. 2005 Nov,131(3):329-37.
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1,10-Epoxyhypocretenolides from the Azorean Endemic Leontodon rigens (Asteraceae)
Zidorn C, Ellmerer EP, Konwalinka G, Ongania KH, Schwaha R, Greil R, Jöhrer K, Perry NB, Stuppner H
Letters in Organic Chemistry. Volume 2, Number 5, August 2005 , pp. 461-464(4).
Expression levels of CD38 in tumor cells and T-cells are of prognostic value in B-CLL
Tinhofer, I, Rubenzer, G, Egle, A, Greil, R
BLOOD. 2005, 106(11): 347A-347A.
Treatment of advanced Hodgkinxxxs disease with COPP/ABV/IMEP versus COPP/ABVD and consolidating radiotherapy: final results of the German Hodgkinxxxs Lymphoma Study Group HD6 trial
Sieber, M, Tesch, H, Pfistner, B, Rueffer, U, Paulus, U, Munker, R, Hermann, R, Doelken, G, Koch, P, Oertel, J, Roller, S, Worst, P, Bischof, H, Glunz, A, Greil, R, von Kalle, K, Schalk, KP, Hasenclever, D, Brosteanu, O, Duehmke, E, Georgii, A, Engert, A, Loeffler, M, Diehl, V
ANN ONCOL. 2004, 15(2): 276-282.
Treatment of advanced Hodgkin's disease with COPP/ABV/IMEP versus COPP/ABVD and consolidating radiotherapy: final results of the German Hodgkin's Lymphoma Study Group HD6 trial.
Sieber M, Tesch H, Pfistner B, Rueffer U, Paulus U, Munker R, Hermann R, Doelken G, Koch P, Oertel J, Roller S, Worst P, Bischof H, Glunz A, Greil R, von Kalle K, Schalk KP, Hasenclever D, Brosteanu O, Duehmke E, Georgii A, Engert A, et al.
Ann Oncol. 2004 Feb,15(2):276-82.
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Transendothelial migration of myeloma cells is increased by tumor necrosis factor (TNF)-alpha via TNF receptor 2 and autocrine up-regulation of MCP-1.
Jöhrer K, Janke K, Krugmann J, Fiegl M, Greil R.
Clin Cancer Res. 2004 Mar 15,10(6):1901-10.
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Unfavourable prognosis of patients with trisomy 18q21 detected by fluorescence in situ hybridisation in t(11,18) negative, surgically resected gastrointestinal B cell lymphomas.
Krugmann J, Tzankov A, Dirnhofer S, Fend F, Greil R, Siebert R, Erdel M.
J Clin Pathol. 2004 Apr,57(4):360-4.
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Quality of life of patients with chronic lymphocytic leukemia: results of a longitudinal investigation over 1 yr.
Holzner B, Kemmler G, Kopp M, Nguyen-Van-Tam D, Sperner-Unterweger B, Greil R.
Eur J Haematol. 2004 Jun,72(6):381-9.
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Normative data for functional assessment of cancer therapy--general scale and its use for the interpretation of quality of life scores in cancer survivors.
Holzner B, Kemmler G, Cella D, De Paoli C, Meraner V, Kopp M, Greil R, Fleischhacker WW, Sperner-Unterweger B.
Acta Oncol. 2004,43(2):153-60.
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Elevated levels of soluble CD44 are associated with advanced disease and in vitro proliferation of neoplastic lymphocytes in B-cell chronic lymphocytic leukaemia.
Eisterer W, Bechter O, Söderberg O, Nilsson K, Terol M, Greil R, Thaler J, Herold M, Finke L, Günthert U, Montserrat E, Stauder R.
Leuk Res. 2004 Oct,28(10):1043-51.
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Biomarkers in non-small cell lung cancer prevention.
Hilbe W, Dirnhofer S, Greil R, Wöll E.
Eur J Cancer Prev. 2004 Oct,13(5):425-36.
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Is higher income and educational status associated with poorer outcome in patients with Hodgkin's disease?
Holzner B, Fischhofer M, Kemmler G, Kopp M, Sperner-Unterweger B, Krugmann J, Dirnhofer S, Greil R.
Eur J Haematol. 2004 Nov,73(5):318-24.
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Tetrocarcin-A--induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2--independent pathway.
Anether G, Tinhofer I, Senfter M, Greil R.
Blood. 2003 Jun 1,101(11):4561-8. Epub 2003 Jan 30.
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A randomized study comparing interferon (IFN alpha) plus low-dose cytarabine and interferon plus hydroxyurea (HU) in early chronic-phase chronic myeloid leukemia (CML).
Kühr T, Burgstaller S, Apfelbeck U, Linkesch W, Seewann H, Fridrik M, Michlmayr G, Krieger O, Lutz D, Lin W, Pont J, Köck L, Abbrederis K, Baldinger C, Buder R, Geissler D, Hausmaninger H, Lang A, Zabernigg A, Duba C, Hilbe W, Eisterer W, et al.
Leuk Res. 2003 May,27(5):405-11.
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Prognostic significance of CD20 expression in classical Hodgkin lymphoma: a clinicopathological study of 119 cases.
Tzankov A, Krugmann J, Fend F, Fischhofer M, Greil R, Dirnhofer S.
Clin Cancer Res. 2003 Apr,9(4):1381-6.
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Longer failure-free survival interval of Epstein-Barr virus-associated classical Hodgkin's lymphoma: a single-institution study.
Krugmann J, Tzankov A, Gschwendtner A, Fischhofer M, Greil R, Fend F, Dirnhofer S.
Mod Pathol. 2003 Jun,16(6):566-73.
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Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets and therapeutic tools.
Greil R, Anether G, Johrer K, Tinhofer I.
J Leukoc Biol. 2003 Sep,74(3):311-30.
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Tuning the rheostat of the myelopoietic system via Fas and TRAIL.
Greil R, Anether G, Johrer K, Tinhofer I.
Crit Rev Immunol. 2003,23(4):301-22.
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Rapidly alternating COPP/ABV/IMEP is not superior to conventional alternating COPP/ABVD in combination with extended-field radiotherapy in intermediate-stage Hodgkin's lymphoma: final results of the German Hodgkin's Lymphoma Study Group Trial HD5.
Sieber M, Tesch H, Pfistner B, Rueffer U, Lathan B, Brosteanu O, Paulus U, Koch T, Pfreundschuh M, Loeffler M, Engert A, Josting A, Wolf J, Hasenclever D, Franklin J, Duehmke E, Georgii A, Schalk KP, Kirchner H, Doelken G, Munker R, Koch P, et al.
J Clin Oncol. 2002 Jan 15,20(2):476-84.
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Interleukin-15 as a potential costimulatory cytokine in CD154 gene therapy of chronic lymphocytic leukemia.
Anether G, Marschitz I, Tinhofer I, Greil R.
Blood. 2002 Jan 15,99(2):722-3.
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The role of soluble CD23 in distinguishing stable and progressive forms of B-chronic lymphocytic leukemia.
Schwarzmeier JD, Shehata M, Hilgarth M, Marschitz I, Louda N, Hubmann R, Greil R.
Leuk Lymphoma. 2002 Mar,43(3):549-54.
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Stressful death of T-ALL tumor cells after treatment with the anti-tumor agent Tetrocarcin-A.
Tinhofer I, Anether G, Senfter M, Pfaller K, Bernhard D, Hara M, Greil R.
FASEB J. 2002 Aug,16(10):1295-7. Epub 2002 Jun 7.
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Multidimensional scaling as a tool for analysing quality of life data.
Kemmler G, Holzner B, Kopp M, DГјnser M, Greil R, Hahn E, Sperner-Unterweger B.
Qual Life Res. 2002 May,11(3):223-33.
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Monoclonal gammopathy of undetermined significance.
Fiegl M, Greil R.
N Engl J Med. 2002 Jun 27,346(26):2087-8, author reply 2087-8.
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The impact of hemoglobin levels on fatigue and quality of life in cancer patients.
Holzner B, Kemmler G, Greil R, Kopp M, Zeimet A, Raderer M, Hejna M, Zöchbauer S, Krajnik G, Huber H, Fleischhacker WW, Sperner-Unterweger B.
Ann Oncol. 2002 Jun,13(6):965-73.
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Intravascular large B-cell lymphoma with a fulminant clinical course: a case report with definite diagnosis post mortem.
Fiegl M, Greil R, Pechlaner C, Krugmann J, Dirnhofer S.
Ann Oncol. 2002 Sep,13(9):1503-6.
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Diffuse large B-cell lymphoma with infiltration-associated peripheral neuropathy and paraneoplastic myopathy with a prolonged course over seven years.
Fiegl M, Muigg A, Smekal A, Krugmannd J, Dirnhofer S, Greil R.
Leuk Lymphoma. 2002 Aug,43(8):1687-90.
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Histone deacetylase inhibitors potently repress CXCR4 chemokine receptor expression and function in acute lymphoblastic leukaemia.
Crazzolara R, Jöhrer K, Johnstone RW, Greil R, Kofler R, Meister B, Bernhard D.
Br J Haematol. 2002 Dec,119(4):965-9.
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Splenectomy versus medical treatment for idiopathic thrombocytopenic purpura.
Gadenstätter M, Lamprecht B, Klingler A, Wetscher GJ, Greil R, Schmid T.
Am J Surg. 2002 Dec,184(6):606-9, discussion 609-10.
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Low-dose radiation is sufficient for the noninvolved extended-field treatment in favorable early-stage Hodgkin's disease: long-term results of a randomized trial of radiotherapy alone.
DГјhmke E, Franklin J, Pfreundschuh M, Sehlen S, Willich N, RГјhl U, MГјller RP, Lukas P, Atzinger A, Paulus U, Lathan B, RГјffer U, Sieber M, Wolf J, Engert A, Georgii A, Staar S, Herrmann R, Beykirch M, Kirchner H, Emminger A, Greil R, et al.
J Clin Oncol. 2001 Jun 1,19(11):2905-14.
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Resveratrol, a tumor-suppressive compound from grapes induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.
Tinhofer I, Bernhard D, Senfter M, Anether G, Loeffler M, Kroemer G, Kofler R, Csordas A, Greil R.
FASEB J. 2001 Jul,15(9):1613-5.
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Primary gastrointestinal B-cell lymphoma. A clincopathological and immunohistochemical study of 61 cases with an evaluation of prognostic parameters.
Krugmann J, Dirnhofer S, Gschwendtner A, Berresheim U, Greil R, Krugmann K, Fend F.
Pathol Res Pract. 2001,197(6):385-93.
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Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts.
Bernhard D, Skvortsov S, Tinhofer I, HГјbl H, Greil R, Csordas A, Kofler R.
Cell Death Differ. 2001 Oct,8(10):1014-21.
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Quality of life measurement in oncology--a matter of the assessment instrument?
Holzner B, Kemmler G, Sperner-Unterweger B, Kopp M, DГјnser M, Margreiter R, Marschitz I, Nachbaur D, Fleischhacker WW, Greil R.
Eur J Cancer. 2001 Dec,37(18):2349-56.
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Epstein-Barr virus-associated extranodal NK/T-cell lymphoma, nasal type of the hypopharynx in a renal allograft recipient: case report and review of literature.
Stadlmann S, Fend F, Moser P, Obrist P, Greil R, Dirnhofer S.
Hum Pathol. 2001 Nov,32(11):1264-8.
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Dose escalation of ara-c may improve response rates in a subgroup of chronic myeloid leukemia patients with poor response to interferon-alpha and low-dose ara-C.
Hilbe W, Kühr T, Apfelbeck U, Fridrik M, Seewann H, Stöger M, Linkesch W, Pont J, Baldinger C, Hartner E, Bernhart M, Geissler D, Krieger O, Lang A, Lin W, Ludwig H, Duba C, Greil R, Gast G, Thaler J.
Leuk Lymphoma. 2001 Nov-Dec,42(6):1283-8.
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Stepping up treatment with Rituxan (R) (rituximab, Mabthera (R)) for CLL patients with advanced stage of disease relapsing after or refractory to conventional chemotherapy.
Greil, R, Steurer, M, Egle, A, Stauder, R, Anether, G, Ulmer, L, Tinhofer, I, Gastl, G
BLOOD. 2001, 98(11): 289B-290B.
Gastric cancer cell lines lack Fas ligand (FasL) expression but kill T cells via a FasL independent pathway.
Tinhofer I, Wykypiel H, Marschitz I, Henn T, Greil R.
Gut. 2000 May,46(5):738-40.
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Vinorelbine-gemcitabine in advanced non-small-cell lung cancer (NSCLC): an AASLC phase II trial. Austrian Association for the Study of Lung Cancer.
Krajnik G, Mohn-Staudner A, Thaler J, Greil R, Schmeikal S, Marhold F, Deutsch J, Preiss P, Malayeri R, Schäfer-Prokop C, Wein W, Huber H, Pirker R.
Ann Oncol. 2000 Aug,11(8):993-8.
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Resveratrol causes arrest in the S-phase prior to Fas-independent apoptosis in CEM-C7H2 acute leukemia cells.
Bernhard D, Tinhofer I, Tonko M, HГјbl H, Ausserlechner MJ, Greil R, Kofler R, Csordas A.
Cell Death Differ. 2000 Sep,7(9):834-42.
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Expression of functional interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma.
Tinhofer I, Marschitz I, Henn T, Egle A, Greil R.
Blood. 2000 Jan 15,95(2):610-8.
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Analysis of Bcl-2 protein expression in chronic lymphocytic leukemia. A comparison of three semiquantitation techniques.
Marschitz I, Tinhofer I, Hittmair A, Egle A, Kos M, Greil R.
Am J Clin Pathol. 2000 Feb,113(2):219-29.
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1985 - 1999
Cyclophosphamide, doxorubicin, vincristine, prednisolone (CHOP) versus cyclophosphamide, epirubicin, vincristine, prednisolone, ifosfamide, VP-16, methotrexate, dexamethasone (CEOP/IMVP-Dexa) for aggressive non-Hodgkinxxxs lymphoma. A multicenter randomized trial of the Austrian working party medical oncology.
Fridrik, MA, Hausmaninger, H, Greil, R, Lang, A, Drach, J, Fortelny, A, Krieger, O, Lin, W
BLOOD. 1999, 94(10): 261B-261B.
Retrospective assessment of quality of life and treatment outcome in patients with Hodgkin's disease from 1969 to 1994.
Greil R, Holzner B, Kemmler G, Kopp M, Buchowski A, Oberaigner W, Fritsch E, Dirnhofer S, Rueffer U, Diehl V, Sperner-Unterweger B.
Eur J Cancer. 1999 May,35(5):698-706.
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Thymic Hodgkin's disease--a histological and immunohistochemical study of three cases.
Krugmann J, Feichtinger H, Greil R, Fend F.
Pathol Res Pract. 1999,195(10):681-7.
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Synergistic action of protein kinase C theta and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells.
Villunger A, Ghaffari-Tabrizi N, Tinhofer I, Krumböck N, Bauer B, Schneider T, Kasibhatla S, Greil R, Baier-Bitterlich G, Uberall F, Green DR, Baier G.
Eur J Immunol. 1999 Nov,29(11):3549-61.
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Comparison of two quality-of-life instruments for cancer patients: the functional assessment of cancer therapy-general and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30.
Kemmler G, Holzner B, Kopp M, DГјnser M, Margreiter R, Greil R, Sperner-Unterweger B.
J Clin Oncol. 1999 Sep,17(9):2932-40.
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Urticaria pigmentosa: a clinical, hematopathologic and serologic study of 30 adults.
Topar G, Staudacher C, Geisen F, Gabl C, Fend F, Herold M, Greil R, Fritsch P, Sepp N.
Am J Clin Pathol. 1998 Mar,109(3):279-85.
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Prognosis and management strategies of lymphatic neoplasias in the elderly. I. Aggressive non-Hodgkin's lymphomas.
Greil R.
Oncology. 1998 May-Jun,55(3):189-217.
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Prognosis and management strategies of lymphatic neoplasias in the elderly. II. Hodgkin's disease.
Greil R.
Oncology. 1998 Jul-Aug,55(4):265-75.
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Leg ulcers associated with long-term hydroxyurea therapy.
Weinlich G, Schuler G, Greil R, Kofler H, Fritsch P.
J Am Acad Dermatol. 1998 Aug,39(2 Pt 2):372-4.
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Interferon-alpha for the treatment of elderly patients with chronic myeloid leukaemia.
Hilbe W, Apfelbeck U, Fridrik M, Bernhart M, Niessner H, Abbrederis K, Michlmayr G, Pont J, Linkesch W, Hausmaninger H, Arneitz K, Baldinger C, Duba C, Eisterer W, Greil R, Konwalinka G, Niederwieser D, Gastl G, Thaler J.
Leuk Res. 1998 Oct,22(10):881-6.
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Vinorelbine/gemcitabine in advanced non-small cell lung cancer (NSCLC): a phase I trial.
Krajnik G, Wein W, Greil R, Marhold F, Mohn-Staudner A, Kummer F, Malayeri R, Zöchbauer-Müller S, Huber H, Pirker R.
Eur J Cancer. 1998 Nov,34(12):1977-80.
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Inversion of CD4(+)/CD8(+) ratio in B chronic lymphocytic leukemia correlates with differential sensitivity of CD4(+) and CD8(+) T lymphocytes to the killing efficacy of Fas (APO-1/CD95) ligand(+) tumor cells.
Tinhofer, I, Marschitz, I, Kos, M, Henn, T, Egle, A, Villunger, A, Greil, R
BLOOD. 1998, 92(10): 271B-271B.
Differential sensitivity of CD4+ and CD8+ T lymphocytes to the killing efficacy of Fas (Apo-1/CD95) ligand+ tumor cells in B chronic lymphocytic leukemia.
Tinhofer I, Marschitz I, Kos M, Henn T, Egle A, Villunger A, Greil R.
Blood. 1998 Jun 1,91(11):4273-81.
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Functional granulocyte/macrophage colony stimulating factor receptor is constitutively expressed on neoplastic plasma cells and mediates tumour cell longevity.
Villunger A, Egle A, Kos M, Egle D, Tinhofer I, Henn T, Uberall F, Maly K, Greil R.
Br J Haematol. 1998 Sep,102(4):1069-80.
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On the role and significance of Fas (Apo-1/CD95) ligand (FasL) expression in immune privileged tissues and cancer cells using multiple myeloma as a model.
Greil R, Egle A, Villunger A.
Leuk Lymphoma. 1998 Nov,31(5-6):477-90.
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Interferon-alpha-2C and LD ara-C for the treatment of patients with CML: results of the Austrian multi-center phase II study.
Thaler J, Hilbe W, Apfelbeck U, Linkesch W, Sill H, Seewann H, Pont J, Bernhart M, Stöger M, Niessner H, Abbrederis K, Geissler D, Hausmaninger H, Lin W, Ludwig H, Lang A, Duba C, Fluckinger T, Greil R, Grünewald K, Konwalinka G, Niederwieser D, et al.
Leuk Res. 1997 Jan,21(1):75-80.
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Cytokine priming of the granulocyte respiratory burst in myelodysplastic syndromes.
Zabernigg A, Hilbe W, Eisterer W, Greil R, Ludescher C, Thaler J.
Leuk Lymphoma. 1997 Sep,27(1-2):137-43.
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Fas (Apo-1/CD95) - Ligand expression on neoplastic plasma cells and its role for the expansion of the neoplastic clone.
Fridrik MA, Greil R, Hausmaninger H, Krieger O, Oppitz P, Stöger M, Klocker J, Neubauer M, Helm W, Pont J, Fazeny B, Hudec M, Simonitsch I, Radaszkiewicz T.
Ann Hematol. 1997 Oct,75(4):135-40.
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Fas (Apo-1/CD95) - Ligand expression on neoplastic plasma cells and its role for the expansion of the neoplastic clone.
Greil, R, Villunger, A, Egle, A, Marschitz, L, Kos, M, Bock, G, Ludwig, H, Geley, S, Kofler, R
BLOOD. 1997, 90(10): 1578-1578.
Expression of Apo-1/Fas (CD95), Bcl-2 Bax and Bcl-x in myeloma cell lines: relationship between responsiveness to anti-Fas mab and p53 functional status.
Egle A, Villunger A, Marschitz I, Kos M, Hittmair A, Lukas P, GrГјnewald K, Greil R.
Br J Haematol. 1997 May,97(2):418-28.
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Constitutive expression of Fas (Apo-1/CD95) ligand on multiple myeloma cells: a potential mechanism of tumor-induced suppression of immune surveillance.
Villunger A, Egle A, Marschitz I, Kos M, Böck G, Ludwig H, Geley S, Kofler R, Greil R.
Blood. 1997 Jul 1,90(1):12-20.
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The interleukin 1beta-converting enzyme inhibitor CrmA prevents Apo1/Fas- but not glucocorticoid-induced poly(ADP-ribose) polymerase cleavage and apoptosis in lymphoblastic leukemia cells.
Geley S, Hartmann BL, Kapelari K, Egle A, Villunger A, Heidacher D, Greil R, Auer B, Kofler R.
FEBS Lett. 1997 Jan 27,402(1):36-40.
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Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells.
Villunger A, Egle A, Kos M, Hartmann BL, Geley S, Kofler R, Greil R.
Cancer Res. 1997 Aug 15,57(16):3331-4.
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Constituents of autocrine IL-6 loops in myeloma cell lines and their targeting for suppression of neoplastic growth by antibody strategies.
Villunger A, Egle A, Kos M, Hittmair A, Maly K, Greil R.
Int J Cancer. 1996 Feb 8,65(4):498-505.
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2',2'-Difluorodeoxycytidine (gemcitabine) induces apoptosis in myeloma cell lines resistant to steroids and 2-chlorodeoxyadenosine (2-CdA).
Gruber J, Geisen F, Sgonc R, Egle A, Villunger A, Boeck G, Konwalinka G, Greil R.
Stem Cells. 1996 May,14(3):351-62.
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IL-10 serum levels in B-cell chronic lymphocytic leukaemia.
Egle A, Marschitz I, Posch B, Herold M, Greil R.
Br J Haematol. 1996 Jul,94(1):211-2.
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Modulation of Apo-1/Fas (CD95)-induced programmed cell death in myeloma cells by interferon-alpha 2.
Egle A, Villunger A, Kos M, Böck G, Gruber J, Auer B, Greil R.
Eur J Immunol. 1996 Dec,26(12):3119-26.
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Multimodal therapy in life-threatening cerebral lupus erythematosus: the benefit of cerebrospinal fluid pheresis.
Pfausler B, Bösch S, Grubwieser G, Vollert H, Greil R, Hagn C, Schmutzhard E.
Int Arch Allergy Immunol. 1995 Aug,107(4):592-4.
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Necrotizing vasculitis associated with hepatitis C virus infection: successful treatment of vasculitis with interferon-alpha despite persistence of mixed cryoglobulinemia.
Sepp NT, Umlauft F, Illersperger B, GrГјnewald K, Schuler G, Greil R, Vogel W.
Dermatology. 1995,191(1):43-5.
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Gastric malt lymphoma with crystalline immunoglobulin inclusions and secondary immunoblastic lymphoma in a cervical lymph node.
Fend F, Gabl C, Hittmair A, Greil R, Feichtinger H.
Pathol Res Pract. 1995 Oct,191(10):1053-8.
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Recombinant human erythropoietin in the anemia associated with multiple myeloma or non-Hodgkin's lymphoma: dose finding and identification of predictors of response.
Cazzola M, Messinger D, Battistel V, Bron D, Cimino R, Enller-Ziegler L, Essers U, Greil R, Grossi A, Jäger G, LeMevel A, Najman A, Silingardi V, Spriano M, van Hoof A, Ehmer B.
Blood. 1995 Dec 15,86(12):4446-53.
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Apoptosis and therapy of malignant diseases of the hematopoietic system.
Gruber J, Greil R.
Int Arch Allergy Immunol. 1994 Dec,105(4):368-73.
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Extensive meningeal involvement as the primary manifestation of a systemic small lymphocytic lymphoma: favourable outcome after neuraxial irradiation without chemotherapy.
Soucek D, Ransmayr G, Twerdy K, Zwierzina H, Greil R, Fritsch E, Maier H, Pallua A, Gerstenbrand F.
Br J Haematol. 1993 Apr,83(4):674-5.
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Differential expression of c-myc-mRNA and c-MYC-protein during terminal neoplastic B-cell differentiation.
Greil R, Loidl P, Fasching B, Huber H.
Curr Top Microbiol Immunol. 1992,182:215-21.
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Investigation of nuclear c-MYC oncoprotein expression in human hematopoiesis: suitability of a rapid and reliable semiquantitative evaluation system.
Greil R, Fasching B, Weger A, Loidl P.
Lab Invest. 1992 Feb,66(2):251-60.
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[Urticarial vasculitis as a symptom of Muckle-Wells syndrome?].
Grassegger A, Greil R, Feichtinger J, Fritsch P, Hintner H.
Hautarzt. 1991 Feb,42(2):116-9.
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Expression of the c-myc proto-oncogene in multiple myeloma and chronic lymphocytic leukemia: an in situ analysis.
Greil R, Fasching B, Loidl P, Huber H.
Blood. 1991 Jul 1,78(1):180-91.
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A monoclonal antibody directed against the human intercellular adhesion molecule (ICAM-1) modulates the release of tumor necrosis factor-alpha, interferon-gamma and interleukin 1.
Geissler D, Gaggl S, Möst J, Greil R, Herold M, Dietrich M.
Eur J Immunol. 1990 Dec,20(12):2591-6.
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[Cytologic molecular detection of oncogene expression: possibilities and prospects in hemato-oncology].
Greil R, Fasching B, Huber H.
Acta Med Austriaca. 1990,17(1):6-10.
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Monoclonal antibody B-ly7: a sensitive marker for detection of minimal residual disease in hairy cell leukemia.
Thaler J, Dietze O, Faber V, Greil R, Gastl G, Denz H, Ho AD, Huber H.
Leukemia. 1990 Mar,4(3):170-6.
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Immunohistology for quantification of normal bone marrow lymphocyte subsets.
Thaler J, Greil R, Dietze O, Huber H.
Br J Haematol. 1989 Dec,73(4):576-7.
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In situ hybridization for the detection of low copy numbers of c-abl oncogene mRNA in lymphoma cells: technical approach and comparison with results with anti-oncoprotein antibodies.
Greil R, Fasching B, Huber H.
Lab Invest. 1989 Apr,60(4):574-82.
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Expression of leucocyte function-associated antigen-1 and 7F7-antigen, an adhesion molecule related to intercellular adhesion molecule-1 (ICAM-1) in non-Hodgkin lymphomas and leukaemias: possible influence on growth pattern and leukaemic behaviour.
Stauder R, Greil R, Schulz TF, Thaler J, Gattringer C, Radaskiewicz T, Dierich MP, Huber H.
Clin Exp Immunol. 1989 Aug,77(2):234-8.
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Immunohistological assessment of bone marrow biopsies from patients with hairy cell leukemia: changes following treatment with alpha-2-interferon and deoxycoformycin.
Thaler J, Denz H, Dietze O, Gastl G, Ho AD, Gattringer C, Greil R, Lechleitner M, Huber C, Huber H.
Leuk Res. 1989,13(5):377-83.
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Importance of an 85 kDa membrane glycoprotein for a variety of cell-cell interactions.
Schulz TF, Vogetseder W, Mitterer M, Neumayer HP, Myones BL, Stauder R, Greil R, Böck G, Feichtinger H, Huber H, et al.
Mol Immunol. 1988 Nov,25(11):1053-61.
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Receptors for the third component of complement: their association with maturation stage in non-Hodgkin lymphomas (NHL) and their possible implication with the development of follicular structures.
Greil R, Gattringer C, Schulz T, Knapp W, Radaskiewicz T, Dierich MP, Huber H.
Clin Exp Immunol. 1986 May,64(2):423-31.
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Growth fraction of tumour cells and infiltration density with natural killer-like (HNK1+) cells in non-Hodgkin lymphomas.
Greil R, Gattringer C, Knapp W, Huber H.
Br J Haematol. 1986 Feb,62(2):293-300.
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In situ quantification of T-cell subsets, NK-like cells and macrophages in Hodgkin's disease: quantity and quality of infiltration density depends on histopathological subtypes.
Gattringer G, Greil R, Radaszkiewicz T, Huber H.
Blut. 1986 Jul,53(1):49-58.
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[Studies of immunologic markers in malignant lymphomas: diagnostic and prognostic relevance].
Huber H, Thaler J, Greil R, Gattringer C, Radaszkiewicz T.
Onkologie. 1986 Apr,9(2):108-13.
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[Infiltration pattern of immunocompetent lymphocytes in the tissue of malignant non-Hodgkin's lymphoma: relationship to histological and clinical parameters].
Gattringer C, Radaszkiewicz T, Greil R, Pfaller W, Huber H.
Wien Klin Wochenschr. 1985 Mar 1,97(5):258-63.
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[Rhabdomyolysis as a late complication of anesthesia--a case of malignant hyperthermia?].
Greil R, Gattringer C, Abbrederis K.
Wien Klin Wochenschr. 1985 Nov 8,97(21):813-6.
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